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Protein Overview: EG11978

General Information:
Name(s) found: rfbA / EG11978 [EcoGene]
Description(s) found:
Found 4 descriptions.
SHOW ALL
  • glucose-1-phosphate thymidylyltransferase / Glucose-1-phosphate thymidylyltransferase 1; TDP-glucose pyrophosphorylase; needed for dTDP-L-rhamnose synthesis [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 293 amino acids

    Gene Ontology:
    Cellular Component: cytosol [IDALink to PubMed article]
    Biological Process: extracellular polysaccharide biosynthetic process [IEA]
    lipopolysaccharide biosynthetic process [IEA]
    biosynthetic process [IEA]
    Molecular Function: magnesium ion binding [IEA]
    nucleotidyltransferase activity [IEA]
    glucose-1-phosphate thymidylyltransferase activity [IEA]
    metal ion binding [IEA]
    transferase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKMRKGIILA GGSGTRLYPV TMAVSKQLLP IYDKPMIYYP LSTLMLAGIR DILIISTPQD  60
   61 TPRFQQLLGD GSQWGLNLQY KVQPSPDGLA QAFIIGEEFI GGDDCALVLG DNIFYGHDLP 120
  121 KLMEAAVNKE SGATVFAYHV NDPERYGVVE FDKNGTAISL EEKPLEPKSN YAVTGLYFYD 180
  181 NDVVQMAKNL KPSARGELEI TDINRIYLEQ GRLSVAMMGR GYAWLDTGTH QSLIEASNFI 240
  241 ATIEERQGLK VSCPEEIAFR KGFIDVEQVR KLAVPLIKNN YGQYLYKMTK DSN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..293] PSI-BLAST 90.0 RmlA (RfbA)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • uridylyltransferase activity
    		•  3.74072767898515 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  2.70047942699289 bayes_pls_golite062009
  • UTP:glucose-1-phosphate uridylyltransferase activity
    		•  2.65167602524122 bayes_pls_golite062009
  • UTP-monosaccharide-1-phosphate uridylyltransferase activity
    		•  2.46432078102948 bayes_pls_golite062009
  • UDP-glycosyltransferase activity
    		•  2.33861720107822 bayes_pls_golite062009
  • transferase activity
    		•  2.17535315350752 bayes_pls_golite062009
  • catalytic activity
    		•  1.88676710996045 bayes_pls_golite062009
  • acetylgalactosaminyltransferase activity
    		•  1.33788133706753 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  1.17054423506287 bayes_pls_golite062009
  • polypeptide N-acetylgalactosaminyltransferase activity
    		•  1.10309252319727 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.02084820914491 bayes_pls_golite062009
  • cytidylyltransferase activity
    		•  0.983416157001861 bayes_pls_golite062009
  • mannosyltransferase activity
    		•  0.91123217364068 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  0.897978517422275 bayes_pls_golite062009
  • UDP-N-acetylglucosamine diphosphorylase activity
    		•  0.513376694534047 bayes_pls_golite062009
  • mannose-phosphate guanylyltransferase activity
    		•  0.2363835251362 bayes_pls_golite062009
  • guanylyltransferase activity
    		•  0.0539392112504681 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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    Created and Maintained by: Michael Riffle