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Protein Overview: EG10414

General Information:
Name(s) found: gpt / EG10414 [EcoGene]
Description(s) found:
Found 5 descriptions.
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  • xanthine phosphoribosyltransferase; xanthine-guanine phosphoribosyltransferase / Xanthine phosphoribosyltransferase; xanthine-guanine phosphoribosyltransferase [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 152 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEA]
    cytosol [IDALink to PubMed article]
    extrinsic to membrane [IEA]
    plasma membrane [IEA]
    Biological Process: GMP salvage [IMPLink to PubMed article]
    IMP salvage [IDALink to PubMed article]
    nucleoside metabolic process [IEA]
    XMP salvage [IMPLink to PubMed article]
    purine ribonucleoside salvage [IEA]
    Molecular Function: magnesium ion binding [IEA]
    protein binding [IPILink to PubMed article]
    metal ion binding [IEA]
    xanthine phosphoribosyltransferase activity [IDALink to PubMed article][IEA]
    hypoxanthine phosphoribosyltransferase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEKYIVTWD MLQIHARKLA SRLMPSEQWK GIIAVSRGGL VPGALLAREL GIRHVDTVCI  60
   61 SSYDHDNQRE LKVLKRAEGD GEGFIVIDDL VDTGGTAVAI REMYPKAHFV TIFAKPAGRP 120
  121 LVDDYVVDIP QDTWIEQPWD MGVVFVPPIS GR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..152] PSI-BLAST 30.522879 Xantine-guanine PRTase (XPRTase)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • adenine phosphoribosyltransferase activity
    		•  4.07252508868782 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  3.91023158228049 bayes_pls_golite062009
  • hypoxanthine phosphoribosyltransferase activity
    		•  3.89356447922614 bayes_pls_golite062009
  • transferase activity
    		•  2.73727660668741 bayes_pls_golite062009
  • transferase activity, transferring pentosyl groups
    		•  2.53679639481311 bayes_pls_golite062009
  • catalytic activity
    		•  2.30431811394775 bayes_pls_golite062009
  • uracil phosphoribosyltransferase activity
    		•  2.20660111782431 bayes_pls_golite062009
  • amidophosphoribosyltransferase activity
    		•  1.51802880667162 bayes_pls_golite062009
  • purine binding
    		•  1.3774977535406 bayes_pls_golite062009
  • nucleobase binding
    		•  1.28671115202467 bayes_pls_golite062009
  • ribose phosphate diphosphokinase activity
    		•  1.18255665419929 bayes_pls_golite062009
  • diphosphotransferase activity
    		•  0.882962388159961 bayes_pls_golite062009
  • xanthine phosphoribosyltransferase activity
    		•  0.607713614998293 bayes_pls_golite062009
  • orotate phosphoribosyltransferase activity
    		•  0.148898393751978 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle