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Protein Overview: EG10137

General Information:
Name(s) found: cdd / EG10137 [EcoGene]
Description(s) found:
Found 5 descriptions.
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  • cytidine/deoxycytidine deaminase / Cytidine deaminase; 2-deoxycytidine deaminase; mutants are 5-fluorodeoxycytidine resistant; binds Zn(II) [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 294 amino acids

    Gene Ontology:
    Cellular Component: cytosol [IDALink to PubMed article]
    Biological Process: cytidine metabolic process [IEA]
    nucleobase, nucleoside and nucleotide interconversion [IDALink to PubMed articleLink to PubMed article]
    Molecular Function: pyrimidine nucleoside binding [IDALink to PubMed article]
    zinc ion binding [IDALink to PubMed article][IEA]
    catalytic activity [IEA]
    cytidine deaminase activity [IDALink to PubMed article][IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHPRFQTAFA QLADNLQSAL EPILADKYFP ALLTGEQVSS LKSATGLDED ALAFALLPLA  60
   61 AACARTPLSN FNVGAIARGV SGTWYFGANM EFIGATMQQT VHAEQSAISH AWLSGEKALA 120
  121 AITVNYTPCG HCRQFMNELN SGLDLRIHLP GREAHALRDY LPDAFGPKDL EIKTLLMDEQ 180
  181 DHGYALTGDA LSQAAIAAAN RSHMPYSKSP SGVALECKDG RIFSGSYAEN AAFNPTLPPL 240
  241 QGALILLNLK GYDYPDIQRA VLAEKADAPL IQWDATSATL KALGCHSIDR VLLA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..294] PSI-BLAST 84.69897 Two-domain cytidine deaminase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cytidine deaminase activity
    		•  4.42667374679603 bayes_pls_golite062009
  • deaminase activity
    		•  2.76997916054448 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
    		•  2.27736397496642 bayes_pls_golite062009
  • catalytic activity
    		•  1.70756445127105 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  1.51294035758003 bayes_pls_golite062009
  • IMP cyclohydrolase activity
    		•  1.11605611485835 bayes_pls_golite062009
  • phosphoribosylaminoimidazolecarboxamide formyltransferase activity
    		•  0.827438033765078 bayes_pls_golite062009
  • hydrolase activity
    		•  0.339145951258927 bayes_pls_golite062009
  • cyclohydrolase activity
    		•  0.308525511259279 bayes_pls_golite062009
  • binding
    		•  0.255962198799579 bayes_pls_golite062009
  • hydroxymethyl-, formyl- and related transferase activity
    		•  0.1546696349714 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.85

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle