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Protein Overview: EG12523

General Information:
Name(s) found: nrdG / EG12523 [EcoGene]
Description(s) found:
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  • anaerobic ribonucleotide reductase activating protein / Ribonucleotide reductase activase, generating glycyl radical; contains iron; binds NrdD tightly [EcoGene]
  • ORF_f154 [Escherichia coli] [nr-271106-contam.fasta]
  • anaerobic ribonucleotide reductase activating protein [Escherichia coli K12] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • anaerobic ribonucleotide reductase activating protein [Escherichia coli str. K-12 substr. MG1655] [Ecoli-contam-Dam1-Mind-COMA-MBP-110.fasta]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 154 amino acids

    Gene Ontology:
    Cellular Component: anaerobic ribonucleoside-triphosphate reductase complex [IMPLink to PubMed article]
    Biological Process: oxygen and reactive oxygen species metabolic process [IEA]
    nucleobase, nucleoside and nucleotide interconversion [IMPLink to PubMed article]
    oxidation reduction [IEA]
    Molecular Function: metal ion binding [IEA]
    oxidoreductase activity [IEA]
    iron ion binding [IEA]
    [formate-C-acetyltransferase]-activating enzyme activity [IEA]
    4 iron, 4 sulfur cluster binding [IDALink to PubMed article][IEA]
    iron-sulfur cluster binding [IDALink to PubMed article]
    class III ribonucleotide reductase activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNYHQYYPVD IVNGPGTRCT LFVSGCVHEC PGCYNKSTWR VNSGQPFTKA MEDQIINDLN  60
   61 DTRIKRQGIS LSGGDPLHPQ NVPDILKLVQ RIRAECPGKD IWVWTGYKLD ELNAAQMQVV 120
  121 DLINVLVDGK FVQDLKDPSL IWRGSSNQVV HHLR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..154] PSI-BLAST 21.045757 Structure of the S-adenosylmethionine dependent Enzyme MoaA

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  1.48331922124015 bayes_pls_golite062009
  • binding
    		•  0.237364440524786 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle