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Protein Overview: EG10464

General Information:
Name(s) found: lpxL / EG10464 [EcoGene]
Description(s) found:
Found 5 descriptions.
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  • lauryl-acyl carrier protein (ACP)-dependent acyltransferase / Lipid A synthesis, KDO2-lipid IVA lauroyl-ACP acyltransferase; not under heat shock regulation; membrane protein affecting cell division, growth, and high-temperature survival [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 306 amino acids

    Gene Ontology:
    Cellular Component: Gram-negative-bacterium-type cell wall [IEA]
    membrane [IDALink to PubMed article][IEA]
    integral to membrane [IEA]
    plasma membrane [IEA]
    Biological Process: lipopolysaccharide core region biosynthetic process [IEA]
    lipid A biosynthetic process [IMPLink to PubMed article]
    response to stress [IEA]
    Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups [IEA]
    transferase activity [IDALink to PubMed article][IEA]
    acyltransferase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTNLPKFSTA LLHPRYWLTW LGIGVLWLVV QLPYPVIYRL GCGLGKLALR FMKRRAKIVH  60
   61 RNLELCFPEM SEQERRKMVV KNFESVGMGL METGMAWFWP DRRIARWTEV IGMEHIRDVQ 120
  121 AQKRGILLVG IHFLTLELGA RQFGMQEPGI GVYRPNDNPL IDWLQTWGRL RSNKSMLDRK 180
  181 DLKGMIKALK KGEVVWYAPD HDYGPRSSVF VPLFAVEQAA TTTGTWMLAR MSGACLVPFV 240
  241 PRRKPDGKGY QLIMLPPECS PPLDDAETTA AWMNKVVEKC IMMAPEQYMW LHRRFKTRPE 300
  301 GVPSRY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..306] FFAS03 2.21 Glycerol-3-phosphate (1)-acyltransferase


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle