Protein Overview: GEFB_DICDI

General Information:
Name(s) found:	GEFB_DICDI [Swiss-Prot]
Description(s) found: Found 5 descriptions. SHOW ALL	Ras guanine nucleotide exchange factor B OS=Dictyostelium discoideum GN=gefB PE=2 SV=1 [Swiss-Prot]
Organism:	Dictyostelium discoideum
Length:	1529 amino acids
Gene Ontology:
Cellular Component:	intracellular [IC]
Biological Process:	aggregation involved in sorocarp development [IMP] multicellular organismal development [IMP] positive regulation of endocytosis [IMP] negative regulation of cellular component movement [IMP] [NOT]cytokinesis [IMP] actin filament organization [IMP] Ras protein signal transduction [ISS] positive regulation of adenylate cyclase activity [IMP] cortical actin cytoskeleton organization [IMP] [NOT]chemotaxis [IMP] cellular component movement [IMP] regulation of small GTPase mediated signal transduction [IEA] phagocytosis [IMP] positive regulation of phagocytosis [IMP] sexual reproduction [IEP] positive regulation of protein kinase B signaling cascade [IMP]
Molecular Function:	guanyl-nucleotide exchange factor activity [IGI][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVVILWGWNE NRFNTLDQVI SFDFIEENKK LYLKILENEK QQKIYNISNL IGRRMDNYRD  60
   61 NNNNNGNGSN INNNGIIINS SMGSQYFNLN KGIIIVESDN ETFLIEEIDY LGKFPILKQF 120
  121 IKCEEFIGIS TLEIISNIEK QLSNLVNLKS NTTEQTDRKY KTNLIDFKES IIQLEKDCKN 180
  181 LLKQSNLINP SIKYSVVKSV KFLLKEIKFE FYHGDINIKR IELFQQLKKF LKIHFWNNPN 240
  241 LILNSGSNID MTDSNDSISS EEINSPNDLN LSLSSFPSIS SPSNSSYNNI NTLTFSNNNN 300
  301 NNNNNSNNNN NNNNNNNNNN SIINSNNNNN SNNNSNISNS SNNNNNNSNN SNNISINVSK 360
  361 TGNNSVINSP TQSSSCYIDC DDTMSNYTDC TNTTNTNSTT TTTTTTTTYG NNLNVYNNNN 420
  421 NNNTNNNNNN VPYKKPALKM MKSPSFKIQL IQEVYLEIMD QCKKIQNYLY ELLDTYLTDE 480
  481 EYINNNNNNN NKDISILFEN NTSYCIAQEI FISLIKNSND FLYQVQLIDL TDTRKKSKEL 540
  541 SEVSNQLFYS TQQLFPSISD HLDFIEMDIF TNNNTTTTTT TTTTTTNTTT NPSNTIKSSH 600
  601 SSLLSSSYSS SKDDDIVLTI NKVLSKLDTF SKEYTKLIGN NLSSNYYVDS GNNNESVSSP 660
  661 KCGLFLSHSL STDSPMTYVK RNTSSGSSAS TSSYTTPVSS SASLSFSSST QTPSSAASQH 720
  721 HIQQILQQQQ QQQQQQQQQQ QQQQPQQIQS QSQQQHQQQQ QQQQQQQQQQ QQQQQQQQQQ 780
  781 QQQQIQSQSQ QQQQLNRKPH YSSISPTSML VYNATGGKFG VVNQNNNSAE STPTFQLNTM 840
  841 DILNSLMGKE GQNSNTNNAN NPNNNNNNNN NNNNNNNNNN NNNNNNENKN ENKNETNKSG 900
  901 HNYNNSSTST LSSSTTIGDL ANVSSTNSPN SSTPNLLLPP HQFHNHNREY NHSHHHLLSS 960
  961 SSNNVMINNR SIGKSFSTGN FSQPQPIMPS NGIGGSGGGG LGTTLSVGNG GIVGGLQSRS1020
 1021 SSFEENQLQY AIESFMEVYN HLTSKDKVDT SIWLEEEKED INVYYINNTN IDDKFYRSIK1080
 1081 YASLNQLILK LTCESNTELR FTKTFITTYR SFTTGDIFLM KLIQRYFTPN LKNIVPYQFV1140
 1141 QKIQIPIQLR VLNVLRLWIE QYPSDFQQPP QITTQSTQPI QNSTTQPQPQ PQPQQPQPQL1200
 1201 QQSTNLQNST IQQPSLFKML TAFLNSTRRN GHGQYSDLIL KKFKQQKQKD RLQLPIINNG1260
 1261 QGIPKAKIFW MKYSTEFIFS QSSTDIAEQL TLLDFDSYKS IEEIELLNQA WSKPDQKTNT1320
 1321 PNIASMVNRF NSFSSFVSWA ILRENDIKQR SKMMLKMIKI CYALYKLSNF NGLLAGLSGL1380
 1381 MASGVYRLNH TKSLISKQYQ KKFDFLCKFL DTKKSHKVYR DIIHSTCPPL IPYLGIYLTD1440
 1441 LTFIEDGNQD EIKGLINFKK REMIFNTILE IQQYQQQGYT IKPKPSVLGF LCELPHMSDK1500
 1501 KKFEDDTYEQ SILLEPKNST KLEVMNAKK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.79

Protein Overview: GEFB_DICDI

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: