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Protein Overview: LUP1_ARATH

General Information:
Name(s) found: LUP1_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|75268170|sp|Q9C5M3.1|LUP1_ARATH RecName: Full=Lupeol synthase 1; Short=AtLUP1 [NCBI NR]
  • gi|30699380|ref|NP_849903.1| LUP1 (LUPEOL SYNTHASE 1); beta-amyrin synthase/ lupeol synthase [Arabidopsis thaliana] [NCBI NR]
  • gi|23296982|gb|AAN13216.1| putative lupeol synthase [Arabidopsis thaliana] [NCBI NR]
  • gi|15450513|gb|AAK96549.1| At1g78970/YUP8H12R_28 [Arabidopsis thaliana] [NCBI NR]
  • gi|15219261|ref|NP_178018.1| LUP1 (LUPEOL SYNTHASE 1); beta-amyrin synthase/ lupeol synthase [Arabidopsis thaliana] [NCBI NR]
  • gi|13430470|gb|AAK25857.1|AF360147_1 putative lupeol synthase [Arabidopsis thaliana] [NCBI NR]
  • Lupeol synthase 1 OS=Arabidopsis thaliana GN=LUP1 PE=1 SV=1 [Swiss-Prot]
  • putative lupeol synthase [Arabidopsis thaliana]gi|13430470|gb|AAK25857.1| putative lupeol synthase [Arabidopsis thaliana]gi|15450513|gb|AAK96549.1| At1g78970/YUP8H12R_28 [Arabidopsis thaliana]gi|30699380|ref|NP_849903.1| lupeol synthase (LUP1) / 2,3-ox [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Lupeol synthase (LUP1) [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: ATLUP1, LUP1 | LUP1 (LUPEOL SYNTHASE 1); lupeol synthase | chr1:29708307-29712608 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • LUP1 (LUPEOL SYNTHASE 1); lupeol synthase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • putative lupeol synthase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • At1g78970/YUP8H12R_28 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: LUP1, ATLUP1 | lupeol synthase 1 | chr1:29703414-29707715 FORWARD LENGTH=757 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 757 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: pentacyclic triterpenoid biosynthetic process [IGI][ISS]
    Molecular Function: lupeol synthase activity [IDA][IGI]
    beta-amyrin synthase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWKLKIGKGN GEDPHLFSSN NFVGRQTWKF DHKAGSPEER AAVEEARRGF LDNRFRVKGC  60
   61 SDLLWRMQFL REKKFEQGIP QLKATNIEEI TYETTTNALR RGVRYFTALQ ASDGHWPGEI 120
  121 TGPLFFLPPL IFCLYITGHL EEVFDAEHRK EMLRHIYCHQ NEDGGWGLHI ESKSVMFCTV 180
  181 LNYICLRMLG ENPEQDACKR ARQWILDRGG VIFIPSWGKF WLSILGVYDW SGTNPTPPEL 240
  241 LMLPSFLPIH PGKILCYSRM VSIPMSYLYG KRFVGPITPL ILLLREELYL EPYEEINWKK 300
  301 SRRLYAKEDM YYAHPLVQDL LSDTLQNFVE PLLTRWPLNK LVREKALQLT MKHIHYEDEN 360
  361 SHYITIGCVE KVLCMLACWV ENPNGDYFKK HLARIPDYMW VAEDGMKMQS FGCQLWDTGF 420
  421 AIQALLASNL PDETDDALKR GHNYIKASQV RENPSGDFRS MYRHISKGAW TFSDRDHGWQ 480
  481 VSDCTAEALK CCLLLSMMSA DIVGQKIDDE QLYDSVNLLL SLQSGNGGVN AWEPSRAYKW 540
  541 LELLNPTEFM ANTMVEREFV ECTSSVIQAL DLFRKLYPDH RKKEINRSIE KAVQFIQDNQ 600
  601 TPDGSWYGNW GVCFIYATWF ALGGLAAAGE TYNDCLAMRN GVHFLLTTQR DDGGWGESYL 660
  661 SCSEQRYIPS EGERSNLVQT SWAMMALIHT GQAERDLIPL HRAAKLIINS QLENGDFPQQ 720
  721 EIVGAFMNTC MLHYATYRNT FPLWALAEYR KVVFIVN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..757] PSI-BLAST 1000.0 Structure of human OSC in complex with Lanosterol

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • lanosterol synthase activity
    		•  3.72954210081462 bayes_pls_golite062009
  • oxidosqualene cyclase activity
    		•  3.70516211286781 bayes_pls_golite062009
  • prenyltransferase activity
    		•  3.525366989371 bayes_pls_golite062009
  • isoprenoid binding
    		•  1.59014951619756 bayes_pls_golite062009
  • binding
    		•  0.663474225223042 bayes_pls_golite062009
  • protein prenyltransferase activity
    		•  0.55742738134604 bayes_pls_golite062009
  • catalytic activity
    		•  0.497699107100544 bayes_pls_golite062009
  • protein binding
    		•  0.172880799019885 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.61

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle