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Protein Overview: TPL_ARATH

General Information:
Name(s) found: TPL_ARATH [Swiss-Prot]
Description(s) found:
Found 13 descriptions.
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  • Protein TOPLESS OS=Arabidopsis thaliana GN=TPL PE=1 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 1131 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    cytosol [IDA]
    Biological Process: xylem and phloem pattern formation [IGI]
    primary shoot apical meristem specification [IGI][IMP]
    jasmonic acid mediated signaling pathway [IMP]
    response to auxin stimulus [IPI]
    Molecular Function: protein binding [IPI]
    protein homodimerization activity [IPI]
    transcription repressor activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSLSRELVF LILQFLDEEK FKETVHKLEQ ESGFFFNMKY FEDEVHNGNW DEVEKYLSGF  60
   61 TKVDDNRYSM KIFFEIRKQK YLEALDKHDR PKAVDILVKD LKVFSTFNEE LFKEITQLLT 120
  121 LENFRENEQL SKYGDTKSAR AIMLVELKKL IEANPLFRDK LQFPTLRNSR LRTLINQSLN 180
  181 WQHQLCKNPR PNPDIKTLFV DHSCGPPNGA RAPSPVNNPL LGGIPKAGGF PPLGAHGPFQ 240
  241 PTASPVPTPL AGWMSSPSSV PHPAVSAGAI ALGGPSIPAA LKHPRTPPTN ASLDYPSADS 300
  301 EHVSKRTRPM GISDEVNLGV NMLPMSFSGQ AHGHSPAFKA PDDLPKTVAR TLSQGSSPMS 360
  361 MDFHPIKQTL LLVGTNVGDI GLWEVGSRER LVQKTFKVWD LSKCSMPLQA ALVKEPVVSV 420
  421 NRVIWSPDGS LFGVAYSRHI VQLYSYHGGE DMRQHLEIDA HVGGVNDISF STPNKQLCVI 480
  481 TCGDDKTIKV WDAATGVKRH TFEGHEAPVY SVCPHYKENI QFIFSTALDG KIKAWLYDNM 540
  541 GSRVDYDAPG RWCTTMAYSA DGTRLFSCGT SKDGESFIVE WNESEGAVKR TYQGFHKRSL 600
  601 GVVQFDTTKN RYLAAGDDFS IKFWDMDAVQ LLTAIDGDGG LQASPRIRFN KEGSLLAVSG 660
  661 NENVIKIMAN SDGLRLLHTF ENISSESSKP AINSIAAAAA AAATSAGHAD RSANVVSIQG 720
  721 MNGDSRNMVD VKPVITEESN DKSKIWKLTE VSEPSQCRSL RLPENLRVAK ISRLIFTNSG 780
  781 NAILALASNA IHLLWKWQRN ERNATGKATA SLPPQQWQPA SGILMTNDVA ETNPEEAVPC 840
  841 FALSKNDSYV MSASGGKISL FNMMTFKTMA TFMPPPPAAT FLAFHPQDNN IIAIGMDDST 900
  901 IQIYNVRVDE VKSKLKGHSK RITGLAFSNV LNVLVSSGAD AQLCVWNTDG WEKQRSKVLP 960
  961 LPQGRPNSAP SDTRVQFHQD QAHFLVVHET QLAIYETTKL ECMKQWAVRE SLAPITHATF1020
 1021 SCDSQLVYAS FMDATVCVFS SANLRLRCRV NPSAYLPASL SNSNVHPLVI AAHPQEPNMF1080
 1081 AVGLSDGGVH IFEPLESEGK WGVAPPAENG SASGAPTAPS VGASASDQPQ R

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..132] PSI-BLAST 6.522879 N-terminal domain of Lissencephaly-1 protein (Lis-1)
    2 View Details [133..190] deduced N/A No confident structure predictions are available.
    3 View Details [191..298] PSI-BLAST 61.69897 No description for 3dm0A was found.
    4 View Details [299..681] PSI-BLAST 68.69897 No description for 2ovpB was found.
    5 View Details [682..722] PSI-BLAST 80.69897 No description for 2gnqA was found.
    6 View Details [723..1131] PSI-BLAST 64.522879 Tup1, C-terminal domain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.83

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle