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Protein Overview: LUP2_ARATH

General Information:
Name(s) found: LUP2_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|75247620|sp|Q8RWT0.1|LUP2_ARATH RecName: Full=Lupeol synthase 2; Short=AtLUP2 [NCBI NR]
  • gi|30699377|ref|NP_178017.2| ATLUP2; beta-amyrin synthase/ lupeol synthase [Arabidopsis thaliana] [NCBI NR]
  • gi|21281165|gb|AAM45087.1| putative lupeol synthase [Arabidopsis thaliana] [NCBI NR]
  • gi|20268754|gb|AAM14080.1| putative lupeol synthase [Arabidopsis thaliana] [NCBI NR]
  • Amyrin synthase LUP2 OS=Arabidopsis thaliana GN=LUP2 PE=1 SV=1 [Swiss-Prot]
  • putative lupeol synthase [Arabidopsis thaliana]gi|20268754|gb|AAM14080.1| putative lupeol synthase [Arabidopsis thaliana]gi|30699377|ref|NP_178017.2| lupeol synthase, putative / 2,3-oxidosqualene-triterpenoid cyclase, putative [Arabidopsis thaliana] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Lupeol synthase [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: ATLUP2 | ATLUP2 (Arabidopsis thaliana lupeol synthase 2); lupeol synthase | chr1:29701615-29705917 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • ATLUP2; lupeol synthase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • putative lupeol synthase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: ATLUP2, LUP2 | lupeol synthase 2 | chr1:29696722-29701024 FORWARD LENGTH=763 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 763 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: triterpenoid biosynthetic process [IDA]
    pentacyclic triterpenoid biosynthetic process [IGI][ISS]
    Molecular Function: lupeol synthase activity [IGI]
    beta-amyrin synthase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWKLKIGEGN GEDPYLFSSN NFVGRQTWEF DPKAGTPEER AAVEDARRNY LDNRPRVKGC  60
   61 SDLLWRMQFL KEAKFEQVIP PVKIDDGEGI TYKNATDALR RAVSFYSALQ SSDGHWPAEI 120
  121 TGTLFFLPPL VFCFYITGHL EKIFDAEHRK EMLRHIYCHQ NEDGGWGLHI EGKSVMFCTV 180
  181 LNYICLRMLG EGPNGGRNNA CKRARQWILD HGGVTYIPSW GKIWLSILGI YDWSGTNPMP 240
  241 PEIWLLPSFF PIHLGKTLCY TRMVYMPMSY LYGKRFVGPL TPLIMLLRKE LHLQPYEEIN 300
  301 WNKARRLCAK EDMIYPHPLV QDLLWDTLHN FVEPILTNWP LKKLVREKAL RVAMEHIHYE 360
  361 DENSHYITIG CVEKVLCMLA CWIENPNGDH FKKHLARIPD FMWVAEDGLK MQSFGSQLWD 420
  421 TVFAIQALLA CDLSDETDDV LRKGHSFIKK SQVRENPSGD FKSMYRHISK GAWTLSDRDH 480
  481 GWQVSDCTAE ALKCCMLLSM MPAEVVGQKI DPEQLYDSVN LLLSLQGEKG GLTAWEPVRA 540
  541 QEWLELLNPT DFFTCVMAER EYVECTSAVI QALVLFKQLY PDHRTKEIIK SIEKGVQFIE 600
  601 SKQTPDGSWH GNWGICFIYA TWFALSGLAA AGKTYKSCLA VRKGVDFLLA IQEEDGGWGE 660
  661 SHLSCPEQRY IPLEGNRSNL VQTAWAMMGL IHAGQAERDP TPLHRAAKLI ITSQLENGDF 720
  721 PQQEILGVFM NTCMLHYATY RNIFPLWALA EYRKAAFATH QDL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..763] PSI-BLAST 1000.0 Structure of human OSC in complex with Lanosterol

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • lanosterol synthase activity
    		•  3.72954210081462 bayes_pls_golite062009
  • oxidosqualene cyclase activity
    		•  3.70516211286781 bayes_pls_golite062009
  • prenyltransferase activity
    		•  3.525366989371 bayes_pls_golite062009
  • isoprenoid binding
    		•  1.59014951619756 bayes_pls_golite062009
  • binding
    		•  0.663474225223042 bayes_pls_golite062009
  • protein prenyltransferase activity
    		•  0.55742738134604 bayes_pls_golite062009
  • catalytic activity
    		•  0.497699107100544 bayes_pls_golite062009
  • protein binding
    		•  0.172880799019885 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.43

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle