Protein Overview: IDHP_RAT

General Information:
Name(s) found:	IDHP_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|62079055\|ref\|NP_001014183.1\| isocitrate dehydrogenase 2 (NADP+), mitochondrial [Rattus norvegicus] [NCBI NR] gi\|50370082\|gb\|AAH76398.1\| Isocitrate dehydrogenase 2 (NADP+), mitochondrial [Rattus norvegicus] [NCBI NR] gi\|149057285\|gb\|EDM08608.1\| similar to NADP+-specific isocitrate dehydrogenase, isoform CRA_b [Rattus norvegicus] [NCBI NR] gi\|119364595\|sp\|P56574.2\|IDHP_RAT RecName: Full=Isocitrate dehydrogenase [NADP], mitochondrial; Short=IDH; AltName: Full=Oxalosuccinate decarboxylase; AltName: Full=NADP(+)-specific ICDH; AltName: Full=IDP; AltName: Full=ICD-M; Flags: Precursor [NCBI NR] Isocitrate dehydrogenase [NADP], mitochondrial OS=Rattus norvegicus GN=Idh2 PE=1 SV=2 [Swiss-Prot] Unknown (protein for MGC:94864) [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Hypothetical LOC361596 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 Hypothetical protein [EBI-IPI_rat_3.05_04-04-2005_origrev.fasta] Isocitrate dehydrogenase [NADP], mitochondrial precursor (IDH) (Oxalosuccinate decarboxylase) (NADP(+)-specific ICDH) (IDP) (ICD-M) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Isocitrate dehydrogenase 2 (NADP+), mitochondrial [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] isocitrate dehydrogenase 2 (NADP+), mitochondrial [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] similar to NADP+-specific isocitrate dehydrogenase, isoform CRA_b [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 HYPOTHETICAL PROTEIN [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] hypothetical protein LOC361596 [Rattus norvegicus] [nr-271106-contam.fasta] Similar to NADP+-specific isocitrate dehydrogenase [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Idh2 Isocitrate dehydrogenase [NADP], mitochondrial [rat-ipi-250309-contam.fasta] isocitrate dehydrogenase 2 (NADP+), mitochondrial precursor [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Isocitrate dehydrogenase [NADP], mitochondrial OS=Rattus norvegicus GN=Idh2 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	452 amino acids
Gene Ontology:
Cellular Component:	mitochondrion [UNKNOWN][IEA] mitochondrial inner membrane [UNKNOWN]
Biological Process:	glyoxylate cycle [IEA] isocitrate metabolic process [ISS] tricarboxylic acid cycle [IEA] oxidation reduction [IEA] 2-oxoglutarate metabolic process [ISS]
Molecular Function:	magnesium ion binding [ISS] oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [IEA] oxidoreductase activity [IEA] NAD or NADH binding [IEA] isocitrate dehydrogenase (NADP+) activity [UNKNOWN][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGYLRAVSS LCRASGSTRT WAPAALNVPS WPEQPRRHYA EKRIKVEKPV VEMDGDEMTR  60
   61 IIWQFIKEKL ILPHVDVQLK YFDLGLPNRD QTNDQVTIDS ALATQKYSVA VKCATITPDE 120
  121 ARVEEFKLKK MWKSPNGTIR NILGGTVFRE PIICKNIPRL VPGWTKPITI GRHAHGDQYK 180
  181 ATDFVVDRAG MFKLVFTPKD GSGAKEWEVY NFPAGGVGMG MYNTDESISG FAHSCFQYSI 240
  241 QKKWPLYLST KNTIMKAYDG RFKDIFQEIF DKHYKTDFDK NKIWYEHRLI DDMVAQVLKS 300
  301 SGGFVWACKN YDGDVQSDIL AQGFGSLGLM TSVLVCPDGK TIEAEAAHGT VTRHYREHQK 360
  361 GRPTSTNPIA SIFAWTRGLE HRGKLDGNQD LIRFAQTLEK VCVQTVESGA MTKDLAGCIH 420
  421 GLSNVKLNEH FLNTTDFLDT IKSNLDRALG KQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.53

Protein Overview: IDHP_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: