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Protein Overview: gi|21489908

General Information:
Name(s) found: gi|21489908 [NCBI NR]
Description(s) found:
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  • gi|21489908|gb|AAM55244.1|AF520715_1 MICAL long isoform [Drosophila melanogaster] [NCBI NR]
  • MICAL long isoform [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • MICAL long isoform OS=Drosophila melanogaster GN=Mical PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
    • Organism: Drosophila melanogaster
    Length: 4723 amino acids

    Gene Ontology:
    Cellular Component: terminal button [IDA]
    cytosol [NAS]
    plasma membrane [IDA]
    Biological Process: sarcomere organization [IMP]
    axon guidance [IMP][TAS]
    neuron remodeling [IGI][IMP]
    dendrite morphogenesis [IGI][IMP]
    Molecular Function: zinc ion binding [IEA]
    actin binding [ISS]
    oxidoreductase activity [IEA]
    electron carrier activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRQHQRHHQ QHHHLPPHQQ PQQQMPQQQQ QLTAQQQQQQ QLLMAEHAAA AEAAELFDLL  60
   61 CVATTMRQIL ALHRAMCEAV GLRPSPLNDF YPRLKAKVRS WKAQALWKKF DARAAHRVYG 120
  121 KGAACTGTRV LVIGAGPCGL RTAIEAQLLG AKVVVLEKRD RITRNNVLHL WPFVITDLRN 180
  181 LGAKKFYGKF CAGSIDHISI RQLQCMLLKV ALLLGVEIHE GVSFDHAVEP SGDGGGWRAA 240
  241 VTPADHPVSH YEFDVLIGAD GKRNMLDFRR KEFRGKLAIA ITANFINKKT EAEAKVEEIS 300
  301 GVAFIFNQAF FKELYGKTGI DLENIVYYKD ETHYFVMTAK KHSLIDKGVI IEDMADPGEL 360
  361 LAPANVDTQK LHDYAREAAE FSTQYQMPNL EFAVNHYGKP DVAMFDFTSM FAAEMSCRVI 420
  421 VRKGARLMQC LVGDSLLEPF WPTGSGCARG FLSSMDAAYA IKLWSNPQNS TLGVLAQRES 480
  481 IYRLLNQTTP DTLQRDISAY TVDPATRYPN LNRESVNSWQ VKHLVDTDDP SILEQTFMDT 540
  541 HALQTPHLDT PGRRKRRSGD LLPQGATLLR WISAQLHSYQ FIPELKEASD VFRNGRVLCA 600
  601 LINRYRPDLI DYAATKDMSP VECNELSFAV LERELHIDRV MSAKQSLDLT ELESRIWLNY 660
  661 LDQICDLFRG EIPHIKHPKM DFSDLRQKYR INHTHAQPDF SKLLATKPKA KSPMQDAVDI 720
  721 PTTVQRRSVL EEERAKRQRR HEQLLNIGGG AAGAAAGVAG SGTGTTTQGQ NDTPRRSKKR 780
  781 RQVDKTANIE ERQQRLQEIE ENRQERMSKR RQQRCHQTQN FYKSLQLLQA GKLLREGGEA 840
  841 GVAEDGTPFE DYSIFLYRQQ APVFNDRVKD LERKLLFPDR ERGDIPSALP RTADEQFSDR 900
  901 IKNMEQRMTG RGGLGGDKKP KDLMRAIGKI DSNDWNVREI EKKIELSKKT EIHGPKGREK 960
  961 VPKWSKEQFQ ARQHKMSKPQ RQDSREAEKF KDIDQTIRNL DKQLKEGHNL DVGERGRNKV1020
 1021 ASIAGQFGKK DEANSDEKNA GSSNATTNTN NTVIPKSSSK VALAFKKQAA SEKCRFCKQT1080
 1081 VYPMEKTTVE GLVLHRNCLK CHHCHTNLRL GGYAFDRDDP QGRLYCTQHF RLPPKPLPQR1140
 1141 TNKARKSAAA QPASPAVPPT AGSVPTAAAT SEHMDTTPPR DQVDLLQTSR ANASADAMSD1200
 1201 DEANVIDEHE WSGRNFLPES NNDSQSELSS SDESDTESDS EMFEEADDSP FGAQTLQLAS1260
 1261 DWIGKQYCED SDDSDDFYDS SEDDGKDDTE GEEFKKAREL RRQEVRLQPL PANLPTDTET1320
 1321 EKLKLNVDNK ENMADGSSLK SGNSFESARS QPSTPLSTPT RVEMEQLERD APRKFSSEIE1380
 1381 AISEKLYHMN NMVKMNKDLE VLAKENLVKS GILRKLTLKE KWLAENAAIA AGQKVTPTPS1440
 1441 ATAPGLQPKS KFDEKFEKVV SPPQPVVEPK PKPVIDFNLD ELKPRKPNFE ERPKEQLPRP1500
 1501 ESLKKPPQQK PKGSSTNVSR SNSLKSNASN GSPKVKKAPV SNNSKMQIEG ILDTLRKIQS1560
 1561 QNSSDQDEDM DVDEDVERKP NKELNSKLKE IQASSFAGTM DHIKSQLTMP TVSAQAPPSM1620
 1621 DLSKYFPNQK QEKSSTSSTN KNQVTLKDVN LAKYFPSSPA PQRRTVETVA DRLKKSQTEA1680
 1681 ALAKTKLLED QANNQAEKTK KEVEKEGESK KITKKVADSK AVPPKRQASL DTFSLREHQM1740
 1741 DGALDLTKKK GPTKASAGVK KPAKSGSTTS VTKATATSEG KTIKIVKKIV PKGTKAKKAA1800
 1801 EAAQESAVVE APPEKKPPKD EAERILDEIL GDGEYRSPSS EYQRLFQDEK SPSDLSDNID1860
 1861 RILEESELDV ELGLPKRSSK KLVKTKSLGE GDFDMKPSKE RLTGVQNILK RFESMSSVTS1920
 1921 QNSDEQAGFK LRRMESTTSN LSSLTRSRES LVSVSDSMSD LEKTMDYLRN EWRNEATNFL1980
 1981 QKKRDKFYAK KEEQEKEAKI LAKPDPLDNL PVQYRDSKLA KFFGLAASKS PENRKSPIKK2040
 2041 KKSPSKTPKV TKANNSLEEL AKISNVRQTK KAQPKTLKPV EVKPLKPASP VPDDFEILDL2100
 2101 LEKATEAKEL ERSKTKSPAV ESISQTPKEA IVEISLPVED IKNLPKTGCD KSSNSSRRGS2160
 2161 QSSLIMSRRH SEISLNEKLN QDALAALNQI EKEREAEQVD ELFQSMVEEM EQEPQPTAIV2220
 2221 EPPEEDIDAD SLCTTISKSP SAQPVTVVKR GSSEDQSIEK LFSHFSDEML VNVEFDSNDE2280
 2281 LVGITPRATL VSRNTEDRDY LDKLESLERD EETFQPVVGE KFIQENVQDE VDGLHFPSRP2340
 2341 QRRPKSSSSS SEPSLPVAPQ RLEKKLSKLD PEDMPPSVQD LLQQVYQKNI QPELVEVIPV2400
 2401 EGKQTLRFPS MLAEEDVDEV DHSKEGIKKI ETAPEEVRKV TEPEDVARVI PSPIKPSISQ2460
 2461 SNSLKSENSS GSSLVEIPKI IAPPKSSSKE NSSDWDREKL PASPMPRRRL LPNQTPYKAP2520
 2521 SVASKESSLE WDMEKLPNSP MLPRRNKMRA ISPSTNPVQL LNNLPSDVDD EAAQRRLIED2580
 2581 FEQERRQALI KRDENFEAIA AEQRRRDSLQ SSSNSSSKRS LPPPTPPMMA SRRGTTQDTN2640
 2641 RTQDTASRHE GTPPMFKKLD VDGSGTSMDS TSCSTRRSSF AFIELQDNKP VIVPMPKKLK2700
 2701 LPKPEPPRFV PEPVATDEPV PEVFQGRAWP KTQLEGEVDL GDSDNEDETE KLKKQLPEYA2760
 2761 RSDSPPSAAF KNRKWPDGKT VFDKRAESLE EEDIFEGLPS PRKRGSQRFM DKPRSQSPQP2820
 2821 FKPLANSSRK SSKSFSDLKK GPSLQSLSAQ SSQDTDTLST TTTVATARPA SYANYEDPMD2880
 2881 ASTQALLDRS KRLHNRKRDF VNERVVERNP YMRDVLRSTD RRDYDDVDED LTSYRPRHYA2940
 2941 SSTLNRFPNT TIRKSNNYDY LSPSSDYLSR RSYIPSASAT SSYYPSTTRS SHLSDLFRRR3000
 3001 SPASGTVSAL SGYGNKESCV ISIGLALDRV GHLIESKCTW VRSTKVQTES ESTSPDEVEL3060
 3061 NSATEISTDS EFDNDEIIRQ APKIFIDDTH LRKPTKVQIK STMIGPNAAS AGLHQKQLAA3120
 3121 REKGGSYLQK YQPQPPLPQF RPLVQVDPTL LIGSQRAPLQ NPRPGDYLLN KTASTEGIAS3180
 3181 KKSLGLKKRY LLGEPANGNK IQKSGSTSVL DSRIRSFQSN ISECQKLLNP SSDISAGMRT3240
 3241 FLDRTKLGEG SQTTPGQTNE LIRSATSNVI NDLRVELRIQ KTGSSHSTDN EKENVFVNCK3300
 3301 NELNKGMEYT DAVNATLLDQ LARKSSPTTP TNKTVVEVID LVTPEKPIDI IDLTALETPK3360
 3361 KQLVDGSAMD VDERLTPDSN KISELQQEVK EEPKPDVSRD VKECIPDILG HIKEGTGSKE3420
 3421 PGGEDQQSLL EQSDEEKRDS PEKDVAEHEL YEPDSVQIQV PNIPWEKSKP EVMSTTGSSG3480
 3481 SICSSSDSSS IEDIQHYILE STTSPDTQTV GGKHNVPRLE VHDTSGALMQ VDSLMIVNGK3540
 3541 YIGDPEDVKF LDMPANVIVP PAPALKTNEL DMEDDQEAEA EPVTATPEPV ECTVIEAERR3600
 3601 VTAPPPLPEM GPPKLKFDSK NENKIESLKN LPLIVESNVE HSQAVKPITL NLSNLARTPD3660
 3661 TPTTPTAHDS DKTPTGEILS RGSDSETEHT GTGQVLTETE LSDWTADDCI SENFVDLEFA3720
 3721 LNSNKGTIKR RKDRRRSGAS KLPSGNEVIH ELARQAPVVQ MDGILSAIDI DDIEFMDTGS3780
 3781 EGSCAEAYPA TNTALIQNRG YMEYIEAEPK KTTRKAAPPS SYPGNLPPLM TKRDEKLGVD3840
 3841 YIEQGAYIMH DDAKTPVNEV APAMTQSLTD SITLNELDDD SMIISQTQPT TTEESEALTV3900
 3901 VTSPLDTSSP RVLDQFASML AAGKGDSTPS SSEQQPKTST VTSSSTGPNS STTGNVSKEP3960
 3961 QEEDLQIQFE YVRALQQRIS QISTQRRKSS KGEAPNLQLN SSAPVIESAE DPAKPAEEPL4020
 4021 VSMRPRTTSI SGKVPEIPTL SSKLEEITKE RTKQKDLIHD LVMDKLQSKK QLNAEKRLHR4080
 4081 SRQRSLLTSG YASGSSLSPT PKLAAACSPQ DSNCSSQAHY HASTAEEAPK PPAERPLQKS4140
 4141 ATSTYVSPYR TVQAPTRSAD LYKPRPFSEH IDSNALAGYK LGKTASFNGG KLGDFAKPIA4200
 4201 PARVNRGGGV ATADIANISA STENLRSEAR ARARLKSNTE LGLSPEEKMQ LIRSRLHYDQ4260
 4261 NRSLKPKQLE EMPSGDLAAR ARKMSASKSV NDLAYMVGQQ QQQQVEKDAV LQAKAADFTS4320
 4321 DPNLASGGQE KAGKTKSGRR PKDPERRKSL IQSLSSFFQK GSGSAASSSK EQGGAVAAVH4380
 4381 SEQSERPGTS SSGTPTISDA AGGGGGGGGV FSRFRISPKS KEKSKSCFDL RNFGFGDKDM4440
 4441 LVCNAASPAG ATSASQKNHS QEYLNTTNNS RYRKQTNTAK PKPESFSSSS PQLYIHKPHH4500
 4501 LAAAHPSALD DQTPPPIPPL PLNYQRSDDE SYANETREHK KQRAISKASR QAELKRLRIA4560
 4561 QEIQREQEEI EVQLKDLEAR GVLIEKALRG EAQNIENLDA TKDNDEKLLK ELLEIWRNIT4620
 4621 ALKKRDEELT IRQQELQLEY RHAQLKEELN LRLSCNKLDK SSADVAAEGA ILNEMLEIVA4680
 4681 KRAALRPTAS QLDLTAAGSA STSAEATGIK LTGQPHDHEE SII

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle