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Protein Overview: twk-12

General Information:
Name(s) found: twk-12 / CE37366 [WormBase]
Description(s) found:
Found 13 descriptions.
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  • WBGene00006667 locus:twk-12 potassium channel protein like status:Partially_confirmed UniProt:Q19907 protein_id:CAA98271.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 713 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    Biological Process: potassium ion transport [IEALink to PubMed article]
    Molecular Function: potassium channel activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLFKKIQWF CNLIRLRSYY KFLLLIAYTA FGAWLFRTYE LQADIKRRSV FGNTTNLVRR  60
   61 QLAERWIEMH KDAVLRNDSA LRFRRAAEAV EWLLDELNLS DHIRDLSEET PWTWTGAMFY 120
  121 AGQLYTTIGY GYPTTKTDEG RICTIFYALF GIPCFLMYLK IENAIEWKKD KQLGKRALKM 180
  181 HGLINDSFQS IGKTLSKKMK KYYKKLRRSR VGRILLPTRV TAMKDGFEDP EAAEERKKKP 240
  241 FPIPIAIIML IIWICFSASM FCIWEDTWVF SSAVYFFIVS ISTVGLGDML FRTPDMMVFN 300
  301 FLLILVGLAL LSMCFELITD RVAKWKQKRF DEHIKKVQKM AFQVFEKDPF IEEAPPLGIR 360
  361 MAPNLMQIAA THVSEEKRGF FAEFKDWFAG KVTDNVIQSK LEDSDDESDS EEALEEFDSP 420
  421 QIATVTANDL IVCSNGAATR RVSKQSYALS DISNLSNSKI LPGNNYGQLL DRIKAMEKFK 480
  481 PKKNDLDSRM FAKFLENKKL AKILEQTELR ELATVSCQTD LSGLVVQRRN PKGRHARIGS 540
  541 CSSQSTMSTL LPNKMHAPDE DSVMSFTFGD LKFDYKTEPF IDEYYIRESN HSIFDFDEDE 600
  601 TVRIPQKMLI SRPGMPPPPP SRPLNLASPL RTLLEKEQKY DEDPEIQLTP RRLNSLSDIQ 660
  661 ARKVKLGVDE NLQHARLVCG LLPQDFDSPS TSTSTSMIDS GYELSKRDAS TMA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..413] PSI-BLAST 50.0 Mammalian Shaker Kv1.2 potassium channel- beta subunit complex
    2 View Details [414..454] PSI-BLAST 4.221849 Intermediate gating structure 1 of the inwardly rectifying K+ channel KirBac3.1
    3 View Details [455..556] deduced N/A No confident structure predictions are available.
    4 View Details [557..713] MSA 5.466996 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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