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Protein Overview: Grip128-PC

General Information:
Name(s) found: Grip128-PC / FBpp0099659 [FlyBase]
Description(s) found:
Found 14 descriptions.
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  • The gene Grip128 is referred to in FlyBase by the symbol Dmel\Grip128 (CG9201, FBgn0026433). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15362314..15366117. It has the cytological map location 13C4. There is experimental evidence that it has the molecular function</span>: gamma-tubulin binding. There is experimental evidence that it is involved in the biological process</span>: male meiosis cytokinesis; mitosis; bicoid mRNA localization; mitotic spindle organization; spindle assembly involved in female meiosis II. 5 alleles are reported. The phenotypes of these alleles are annotated with: egg; S2 cell-line; Nebenkern; spermatid; spindle. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 501 amino acids

    Gene Ontology:
    Cellular Component: centrosome [IDA]
    gamma-tubulin ring complex [IPI][ISS][NAS]
    spindle pole [IEA]
    Biological Process: bicoid mRNA localization [IMP]
    mitotic spindle organization [IMP]
    spindle assembly involved in female meiosis II [IMP]
    mitosis [IMP]
    male meiosis cytokinesis [IMP]
    Molecular Function: gamma-tubulin binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGMEDDLLLV EIFNKLQSCP LYQLLLEHAL ESGETQDLLC SVNTLSEMLT SNNEIQLPSL  60
   61 HDELFTQFFA QLKVYCGADN TDYEDEPEPD KDYEDLTVCN RQGIRNHELF AIFTQPLVEQ 120
  121 RLERQRERLK SNPVLMANIL KRLERSTCLQ LKSELPEALR EILRRRQWLA NEYAIRAYCK 180
  181 ETQVAEKMRF LRHTMLLEKY YLFVPYYNAL FVRMEKNNSW ALGSVLTSKL CAVLLPHYPQ 240
  241 LAHYLHVKLI SQINSNSIKV YEALEAIELD FERPMAMHQW YILTPAHMQD YNSVWRLMLK 300
  301 VKWAVWKLEN MQFLRRARFN PCAPLDLIGL TIRRLEIVRF WLIFLINNLH AHIMEAVSRQ 360
  361 FELRIGECKN VRELRIMHDE HLAWLKTHCM LTDEFKAFRV ALDQIFHLVY VLDMEWTTCA 420
  421 SCMHDHDALC LDVTISDDGI DDSETQRRSL EYLALNQVAE IELTYIRCHQ MLADILNTLV 480
  481 HQNDHGFLSA LEETINSSVP H

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..88] MSA 2.132991 View MSA. No confident structure predictions are available.
    2 View Details [89..279] MSA 4.182984 View MSA. No confident structure predictions are available.
    3 View Details [280..501] MSA 3.182986 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.88

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle