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Protein Overview: gi|1929429, gi|7...

General Information:
Name(s) found: gi|7511973 [NCBI NR]
gi|1929429 [NCBI NR]
Description(s) found:
Found 5 descriptions.
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  • pir||T13945 neurofibromin - fruit fly (Drosophila melanogaster) [NCBI NR]
  • gi|1929429|gb|AAB58977.1| neurofibromin [Drosophila melanogaster] [NCBI NR]
    • Organism: Drosophila melanogaster
    Length: 2802 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEA]
    Biological Process: regulation of multicellular organism growth [IMP]
    determination of adult lifespan [IMP]
    perineurial glial growth [IGI]
    regulation of Ras protein signal transduction [IMP]
    positive regulation of adenylate cyclase activity [IMP]
    olfactory learning [IMP]
    Ras protein signal transduction [IGI]
    positive regulation of multicellular organism growth [IMP]
    response to oxidative stress [IMP]
    short-term memory [IMP]
    response to heat [IMP]
    locomotor rhythm [IMP]
    cAMP-mediated signaling [IMP]
    Molecular Function: Ras GTPase activator activity [IDA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQKPGEWAS ALLARFEDQL PNRIGAYGTQ ARMSQDQLVA CLIHISRYRF SLVISGLTKM  60
   61 LQRVNEAALQ NRHEPERCYF ESLVIILTTL ERCLTNQTKD TARFEEAMNV KLLLREISQF 120
  121 VDVQSDSNPN AAQLKALASK VLFALSQNHF SAVFNRISAR IQELTSCSEE NPDYNDIELI 180
  181 QHIDMDMIKL TKLLQETITK FRSKRAPPLI LLYSLEKAIW NWIEYHPQEF QDLQRGTNRD 240
  241 ISTCWEPLMD FVEYFKTENK KSKTLVWPLQ MLLLILNPSC LEAVVNELQQ SEKEKEKDKE 300
  301 KVASKSAQST SRDKDFSAKQ FIESIKRGLG QHSPSKQVTE SAAIACVKLC KASTYINNTD 360
  361 SNNVVFKLVQ FFINDLKALL FNPAKPFSRG QGYNFADIEL MIDCWVSCFR INPHNIEALK 420
  421 VCLNLSSPQA YHFVIVCSLL RLAHIYVDFR LQNKNPFRIV NQPRLSWWPQ TDVVHYRSAE 480
  481 LRALFTDTLN KATQGYIAHT PLRYITSLTL KSKDTQKGLT RAEEGPAHKM LLLLLVRLIH 540
  541 ADPTLLLNTQ GKVAHEVQSS TLELINGLVS LVHQTTMPDV AQEAMEALLA LHAPEKIEVW 600
  601 NPEAPINTFW DVSSQVLFSI SQKLIQHQIA NYTDVLKWLR EILICRNTFL QRHKDYAHVG 660
  661 SQIAICKQAH IKMEVVFFMY LWSVDLDAVL TSLSCFGLLC EEAEICCSSD ELTVGFIMPN 720
  721 YHIYQELAQL STSATDSRIC FFDNTHGNVL SRLTLQKRIM TLLRKIEHCV HGVQPAWEET 780
  781 FRNWEVSSKV LQTYPKCKGE DGQAEVFHRG MGKRRASHQS SEHDLEEQIN EWANMTWFLL 840
  841 ALGGVCLHKR SSSRQMLLQQ SQNNASLGSL AQNSLYSSST SSGHGSLHPS TVSLSTLPPA 900
  901 PPQDVSYCPV TQFVGQLLRL LVCSNEKIGL NIQKNVKELV GEEMSTQLYP ILFDQVRAIV 960
  961 EKFFDQQGQV NVNVTDINTQ FIENTIYIMK SILDPKANKD PNNDQPSPSE HLGVTSIEGM1020
 1021 MLGIVRYVRH LDMTVYAIRI KTKLCQLVEV MMKRRDDLAF RQEMKFRNKL VEYLTDWVMG1080
 1081 TSHQIAPPSS ADAAILTNTS LIFRDLDQAC MEAVAALLRG LPLQPEESDR GDLMDAKSAL1140
 1141 FLKYFTLFMN LLNDCIDSSE AEKEMNNTPL LPPRPRMAAG KLTALRNATI LAMSNLLGAN1200
 1201 IDSGLMHSID LGYNPDLQTR AAFMEVLTQI LQQGTEFDTL AETVLADRFE QLVQLVTMIS1260
 1261 DKGELPIAMA LANVVTTSQM DELARVLVTL FDAKHLLSPL LWNMFYREVE VSDCMQTLFR1320
 1321 GNSLGSKIMA FCFKIYGASY LQMLLEPLIR PLLDEEEETC FEVDPARLDP TEDIEQHRNN1380
 1381 LIALTQKVFD AIINSSDRLP PQLRSMCHCL YQVLSKRFPN LLQNNIGAVG TVIFLRFINP1440
 1441 AIVSPQELGI VDKQVHSSAK RGLMLMSKIL QNIANHVEFS KEQHMLCFND FLRDHFEAGR1500
 1501 RFFIQIASDC ETVDQTSHSM SFISDANVLA LHRLLWTHQE KIGDYLSSSR DHKAVGRRPF1560
 1561 DKMATLLAYL GPPEHKPVDS HMMFSSYARW SSIDMSSTNF EEIMVKHQMH EKEEFKTLKS1620
 1621 MNIFYQAGTS KSGYPVFYYI ARRYKIGETN GDLLIYHVIL TLKPFCHSPF EVVIDFTHTC1680
 1681 SDNRFRTEFL QKWFYVLPTV AYENVHAVYI YNCNSWVREY TKFHDRILAP LKGNRKLLFL1740
 1741 ESPNKLTDFI DAEQQKLPGA TLSLDEDLKV FSNALKLSHK DTKVAIKVGP TALQITSAEK1800
 1801 TKVLAHSVLL NDVYYASEIE EVCLVDDNQF TLSITNESGQ LSFIHNDCDN IVQAIIHIRN1860
 1861 RWELSQPDSV TVHQKIRPKD VPGTLLNMAL LNLGSCDPNL RTAAYNLLCA LTATFDLKIE1920
 1921 GQLLETQGLC IPSNNTIFIK SVSEKLATNE PHLTLEFLEE SIQGFQRTTI ELKHLCLEYM1980
 1981 TPWLKNLVKF CKSNDDSKKL KVSQILDKLI NLTIDQKEMY PSVQAKIWGS IGQIPELIDM2040
 2041 VLDNFLHKSI TYGLGSPQVE IMADTAVALA SANVQLVSKK VITRICRVMD KSCTNPTQYL2100
 2101 EQHMMWDDIA ILGRYLLMLS FNNCLDVATS VPYLFHTITF LVCSGSLSMR ASTHGLVINI2160
 2161 IHSLCTCTNP SFSEEAQRVL RLSLDEFSLP KFYLLFGISK VKSAAVTAFR SSCRHPTDKW2220
 2221 LGNERVTQPL PADRERLSLP SLEVITDALL EIMEACMRDV PDCEWLNTWT SLARSFAFCY2280
 2281 NPALQPRALI VYGCISKSVT DHEVKQLLRI LVKALESFND LILIEALVMC LTRIQPLLRP2340
 2341 ESPIHRALFW VAISVLQLDE ITLYGAGLAL LEQNLHTLKS QGCFDKKETI AEVMMKTREK2400
 2401 LEWHFKQLDH AVGLSFRSNF HFALVGHLIK GFRHPTPTTV SRTSRVLTML LGIIAKPLHR2460
 2461 DKFEVTPDSV AYLTALVAVS EEVRSRCHVK HALPRWPADL SSSVENGEAS GGVQAIGLPL2520
 2521 SRRQKSWDIL DQSALQFARQ HKVPTLQNAR VLFKTQRSFS VPTTKDPNNA TGIEERQERG2580
 2581 SRSSVSNESN VLLDPEVLPD LSIQALVLTV LATLVKYSSD EGETRVLYQY LAEGSVVFPK2640
 2641 VFPVIHSLLD QKINNILSVS HDQVVLNSVQ NIIQNMLASE DPSQQQLHFL QSCGFGGLWR2700
 2701 FAGPFTKYNM MGESSELFVN CLEAMVETCL PGDESAPVPP SPRPYNLSSS LSSLTLGSPT2760
 2761 DKAFSSESLD FYDNCPGSVS SLRRASHSKS RAKHRINDSP SH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.85

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle