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Protein Overview: Mhcl-PC

General Information:
Name(s) found: Mhcl-PC / FBpp0082686 [FlyBase]
Description(s) found:
Found 18 descriptions.
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  • The gene Myosin heavy chain-like is referred to in FlyBase by the symbol Dmel\Mhcl (CG31045, FBgn0026059). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:11894245..11923310. It has the cytological map location 89B2-89B3. Based on sequence similarity, it is predicted to have molecular function</span>: ATPase activity, coupled. The biological processes in which it is involved are not known. 6 alleles are reported. The phenotypes of these alleles are annotated with: ventral nerve cord; peripheral nervous system. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 920 amino acids

    Gene Ontology:
    Cellular Component: myosin complex [ISS]
    Biological Process: NONE FOUND
    Molecular Function: ATP binding [IEA]
    protein binding [IEA]
    ATPase activity, coupled [ISS]
    motor activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWSDKSAVCL PLSGNASVAA SFRNSAQILN LFYGEGHEDF VVPQPILGLL TIGCAIACVR  60
   61 IILFRSGVLS ELEAKRDVLL SDRIIQLQAF CRGYLARKKM SQRRVQELAV RCIQRNVKAF 120
  121 LAVRDWPWWR LLVRVTPLLN VHRTEEQLKT ANEELLMLRA KLEKIECDRS EVKAENQKLE 180
  181 AKLSELTVDL AEERSTAHIA TERLEAETAE RLKLEKELGD QTNKVKNLQE TTEKLEMELI 240
  241 CAKSDLNGIS EDEDAENEDG VGGGVYKLKY ERVARELEFT KRRLHTQHEH DLEQLVALKK 300
  301 HLEMKLSDAY EEVVEQRQVV GQWKRKAQKM TNEMNDLRML LEEQNARNNL LEKKQRKFDA 360
  361 ECQSLQDAVR QERQAKERYG REKDVLQAEK FTLEQTLADT RLDLEFKEEK LASLQRELEE 420
  421 MTFGGGTEEE FAQLRRSKNE TERRAKEQEE ELDEMAGQIQ LLEQAKLRLE MTLETMRKEA 480
  481 RRESQQRDEE LEEVRGNGYK KIKALECQLE TEHEERTLLL REKHELERRL SSMEDRDRVD 540
  541 RDAEEALNQK LRRDLRKYKA LLKDAQTQLE RLKADTPGKT LIRQLRNQLE DAESARSLAM 600
  601 KARQTAEAEL TEVQAMFDES HRARNDAEER ANAAHRDRAE LQAQIEENEE ELGELMKKYS 660
  661 ATVKQLNTEQ INVSEAEFKL NEMEAERNNL KEQVAELQHR LDNVENLGDP SMAMMSKRLE 720
  721 LRTKELESRL ELEQATRARL EVQVNRHKEA LEKLQNEVTQ SKMREMQAQD VIKKSQKSLR 780
  781 DMREEFHAVS SREQESLTRR KDLEKKVEQM ESEGAALKND LRLALQRIAD LQQAMEEEGE 840
  841 EELSESDESL SSVGSISDLE DRLRPVHVKR SSQQSLNGSI GGGGGSVVSS TRTVVFEKDD 900
  901 NSPRYADNEV NSNSRKQHKH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..468] PSI-BLAST 43.69897 Heavy meromyosin subfragment
    2 View Details [469..760] FFAS03 2.72 Tropomyosin
    3 View Details [761..920] PSI-BLAST 6.522879 No description for 2i1jA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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