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Protein Overview: gi|12002996

General Information:
Name(s) found: gi|12002996 [NCBI NR]
Description(s) found:
Found 3 descriptions.
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  • gi|12002996|gb|AAG43431.1| filamin isoform A [Drosophila melanogaster] [NCBI NR]
    • Organism: Drosophila melanogaster
    Length: 2210 amino acids

    Gene Ontology:
    Cellular Component: female germline ring canal inner rim [IDA]
    female germline ring canal outer rim [IDA]
    Biological Process: germline ring canal formation [IMP]
    determination of adult lifespan [IMP]
    protein localization [IMP]
    female germline ring canal formation, actin assembly [IMP]
    female germline ring canal formation [IMP]
    germarium-derived female germ-line cyst encapsulation [IMP]
    olfactory learning [IMP]
    negative regulation of lamellocyte differentiation [IMP]
    learning or memory [IMP]
    Molecular Function: actin binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEAERDLAED AQWKKIQQNT FTRWANEHLK TIDRSINNLE TDLSDGLRLI ALIEVLSQKR  60
   61 MPKYNKRPTF RSQKLENVSV ALKFLQDEGI KIVNIDSSDI VDCKLKLILG LIWTLILHYS 120
  121 ISMPMWDGED DKQLNGSGHT PKQRLLNWIH AKIPDLPINN FTNDWTTGKA VGALVDACAP 180
  181 GLCPDWELWD PKDAVQNASE AMGLADDWLN VRQLIKPEEL VNPNVDEQSM MTYLSQYPNS 240
  241 KLKTGAPLRP KTNPNRVRAY GPGIEPIGPV VGAPANFTVE TFSAGKGSVD VDIQGPNGEI 300
  301 EKADVRFNND KNLTYTVSYI PKSEGSHKVA VKFSGRDIPK SPFPVKVEGH AGDASKVKVT 360
  361 GPGIQPNGVT IKKPTFFDIL AKDAGRGVPE VIIIDPANHK TSVAAKVRQL ENDTWRCEYV 420
  421 TALQGLHSVN VFYAGTPIPN SPFPVKVAPL SDARKVRASG RGLQATGVRV GDDADFKIYT 480
  481 EGAGEGEPEV RVIGPGGMNQ NVMQSKVDGN TYECHYYPTK EGRYVIMVTF AGQEVAKSPF 540
  541 EVKVGPKKES SIVAYGPGLS SGVIGYPAAF VVETNGETGA LGFTVAGPSQ AEIECHDNGD 600
  601 GSALVKYHPT AVGEYAVHIL CDNEDIPKSP FIAQILPRTD FHPELVKASG PGLEKNGVTI 660
  661 NQPTSFTVDP SKAGNAPLDV VVQDVFGTKL PVELKNNPDG TKKVTYTPTS GVPHTVEVNY 720
  721 GGVSTPNSPH RVYVGVPVDA AKVQAFGPWL QPGVRPNAAT HFNVDAREAG DAELKVKIIH 780
  781 EETKIEVPCR IIDNEDNTYS VEVIPPSKGA YTTTMTYGGQ RVPLGEKVVV EQTVDVSKIK 840
  841 VDGLEPSVIM NAATDFMVDM SKVGSNIDSG KLSCAIFDPM GHVLPSKIVQ GPTDDIFRIM 900
  901 YTPFEAGRHT IELMYDNIPV PGSPFVVNVK SGCDPARCKA YGPGLEKGLT NQKNKFTVET 960
  961 KGAGNGGLSL AIEGPSEAKM TCTDNRDGSC DVDYLATDPG EYDITIRFAD KHIPGSPFRV1020
 1021 LVEETVDPSK VKVYGPGIEH GQVRESVPTF FNVDVGEAGP GRIAVKLTNS EGIPVDNLRV1080
 1081 EDKGNCIYAV HYVPPKAGSV LTCQVKFSEV EVPCSPFVMT VFPKSEPTKV KVKGVNEKKK1140
 1141 TPASLPAEFE IDTKQAGQAD INVAIKNPKG KAMQPRLEEV STGTYVVSFV PDECGTYQCS1200
 1201 IKYGDKEIEG SPFKLEAFPT GEAKKCKLVE QAPKIQTSGS QSHLKVDARE AGDGAVTCKI1260
 1261 TNKAGSEIVD IDVIEKDGFF DILYALNDPG DYDINVKFGG KDIPNGSFSI KAVESIEQYS1320
 1321 HSEYIEEHTT KVVQQTTQSE LVTGKSEITY RSVAFEKLPL PTTGGNVTAE VRMPSGKVDK1380
 1381 PVIQDNRDGT VSVKYDPREE GSHELVVKYN GEPVQGSPFK FHVDSITSGY VTAYGPGLTH1440
 1441 GVTGEPANFT ISTKGASAGG LTMAVEGPSK ADINYHDNKD GTVSVQYLPT APGEYQVSVR1500
 1501 FGDKHIKGSP YFAKITGEGR KRNQISVGSC SEVTMPGDIT DDDLRALNAS IQAPSGLEEP1560
 1561 CFLKRMPTGN IGISFTPREI GEHLVSVKRL GKHINNSPFK VTVCEREVGD AKKVKVSGTG1620
 1621 LKEGQTHADN IFSVDTRNAG FGGLSVSIEG PSKAEIQCTD KDDGTLNISY KPTEPGYYIV1680
 1681 NLKFADHHVE GSPFTVKVAG EGSNRKREKI QRERDAVPIT EIGSQCKLTF KMPGITSFDL1740
 1741 AACVTSPSNV TEDAEIQEVE DGLYAVHFVP KELGVHTVSV RYSEMHIPGS PFQFTVGPLR1800
 1801 DSGSHLVKAG GSGLERGVVG EAAEFNVWTR EAGGGSLAIS VEGPSKADIE FKDRKDGSCD1860
 1861 VSYKVTEPGE YRVGLKFNDR HIPDSPFKVY VSPDAGDAHK LEVQQFPQGN IQADAPYQFM1920
 1921 VRKNGAKGEL DAKIVAPSGT DDDCFIQVID GEMYSVRFYP RENGIHAIHV KFNGVHIPDS1980
 1981 PFRIKVGKDV ADPAAVHASG NGLDEVKTGH KADFIINTCN AGVGTLAVSI DGPSKVAMDC2040
 2041 TEVEEGYKVR YTPLLPGEHY ITVKYNNMHI VGSPFKVNAT GDKLADEGAQ ETSTVIVETV2100
 2101 QKVAKGGKNT GVHLPTFKSD ASKVVSKGMG LKKAYIGKQN QFSISATDAG NNILYVGMYG2160
 2161 PKGPCEEFHV KHAGHNNYNV QYLVRDRGQY VLLIKWGEEH IPGSPFQIDV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle