YRC Public Data Repository - View Philius Transmembrane Prediction Details

Prediction Overview

Protein:	NPC1
Protein type:	Transmembrane with Signal Peptide
Type Confidence:	0.99
Topology Confidence:	0.82
From Publication:	Reynolds et al. (2008)

Predicted Protein Segments [Show List]:

Predicted Protein Segments [Hide List]:

Type	Start	End	Confidence
Signal Peptide	1	22	0.99
N-region	1	13
H-region	14	19
C-region	20	22
Cleavage Site	22	23
Non-Cytoplasmic	23	268	0.99
Transmembrane Helix	269	291	0.93
Cytoplasmic	292	345	0.97
Transmembrane Helix	346	371	0.83
Non-Cytoplasmic	372	620	0.99
Transmembrane Helix	621	642	0.90
Cytoplasmic	643	653	0.89
Transmembrane Helix	654	678	0.88
Non-Cytoplasmic	679	683	0.78
Transmembrane Helix	684	706	0.90
Cytoplasmic	707	733	0.86
Transmembrane Helix	734	754	0.82
Non-Cytoplasmic	755	761	0.63
Transmembrane Helix	762	785	0.86
Cytoplasmic	786	835	0.90
Transmembrane Helix	836	853	0.86
Non-Cytoplasmic	854	1097	0.80
Transmembrane Helix	1098	1117	0.91
Cytoplasmic	1118	1124	0.66
Transmembrane Helix	1125	1147	0.88
Non-Cytoplasmic	1148	1152	0.74
Transmembrane Helix	1153	1174	0.84
Cytoplasmic	1175	1191	0.82
Transmembrane Helix	1192	1216	0.83
Non-Cytoplasmic	1217	1227	0.73
Transmembrane Helix	1228	1250	0.88
Cytoplasmic	1251	1278	0.86

Prediction Image Map

(Place mouse over segments for confidence values.)

Prediction Sequence Map

Legend: Transmembrane Helix, Non-Cytoplasmic, Cytoplasmic, Signal Peptide

(Place mouse over sequence for confidence values.)

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTARGLALGL LLLLLCPAQV FSQSCVWYGE CGIAYGDKRY NCEYSGPPKP LPKDGYDLVQ  60
   61 ELCPGFFFGN VSLCCDVRQL QTLKDNLQLP LQFLSRCPSC FYNLLNLFCE LTCSPRQSQF 120
  121 LNVTATEDYV DPVTNQTKTN VKELQYYVGQ SFANAMYNAC RDVEAPSSND KALGLLCGKD 180
  181 ADACNATNWI EYMFNKDNGQ APFTITPVFS DFPVHGMEPM NNATKGCDES VDEVTAPCSC 240
  241 QDCSIVCGPK PQPPPPPAPW TILGLDAMYV IMWITYMAFL LVFFGAFFAV WCYRKRYFVS 300
  301 EYTPIDSNIA FSVNASDKGE ASCCDPVSAA FEGCLRRLFT RWGSFCVRNP GCVIFFSLVF 360
  361 ITACSSGLVF VRVTTNPVDL WSAPSSQARL EKEYFDQHFG PFFRTEQLII RAPLTDKHIY 420
  421 QPYPSGADVP FGPPLDIQIL HQVLDLQIAI ENITASYDNE TVTLQDICLA PLSPYNTNCT 480
  481 ILSVLNYFQN SHSVLDHKKG DDFFVYADYH THFLYCVRAP ASLNDTSLLH DPCLGTFGGP 540
  541 VFPWLVLGGY DDQNYNNATA LVITFPVNNY YNDTEKLQRA QAWEKEFINF VKNYKNPNLT 600
  601 ISFTAERSIE DELNRESDSD VFTVVISYAI MFLYISLALG HIKSCRRLLV DSKVSLGIAG 660
  661 ILIVLSSVAC SLGVFSYIGL PLTLIVIEVI PFLVLAVGVD NIFILVQAYQ RDERLQGETL 720
  721 DQQLGRVLGE VAPSMFLSSF SETVAFFLGA LSVMPAVHTF SLFAGLAVFI DFLLQITCFV 780
  781 SLLGLDIKRQ EKNRLDIFCC VRGAEDGTSV QASESCLFRF FKNSYSPLLL KDWMRPIVIA 840
  841 IFVGVLSFSI AVLNKVDIGL DQSLSMPDDS YMVDYFKSIS QYLHAGPPVY FVLEEGHDYT 900
  901 SSKGQNMVCG GMGCNNDSLV QQIFNAAQLD NYTRIGFAPS SWIDDYFDWV KPQSSCCRVD 960
  961 NITDQFCNAS VVDPACVRCR PLTPEGKQRP QGGDFMRFLP MFLSDNPNPK CGKGGHAAYS1020
 1021 SAVNILLGHG TRVGATYFMT YHTVLQTSAD FIDALKKARL IASNVTETMG INGSAYRVFP1080
 1081 YSVFYVFYEQ YLTIIDDTIF NLGVSLGAIF LVTMVLLGCE LWSAVIMCAT IAMVLVNMFG1140
 1141 VMWLWGISLN AVSLVNLVMS CGISVEFCSH ITRAFTVSMK GSRVERAEEA LAHMGSSVFS1200
 1201 GITLTKFGGI VVLAFAKSQI FQIFYFRMYL AMVLLGATHG LIFLPVLLSY IGPSVNKAKS1260
 1261 CATEERYKGT ERERLLNF