YRC Public Data Repository - Protein Structure Prediction

Protein:	CAPZB_RAT
Organism:	Rattus norvegicus
Length:	272 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CAPZB_RAT.

Description	E-value	Query Range	Subject Range
gi\|55732943\|emb\|... - hypothetical protein [Pongo pygmaeus] gi\|55732943 - gi\|55732943\|emb\|CAH93159.1\| hypothetical protein [Pongo abelii]	510.0	[0..1]	[272..1]
gi\|73950682 - gi\|73950682\|ref\|XP_535384.2\| PREDICTED: similar to F-actin capping protein beta subunit [Canis famil...	499.0	[0..1]	[272..9]
CAPZB_BOVIN - F-actin-capping protein subunit beta OS=Bos taurus GN=CAPZB PE=1 SV=1	499.0	[0..2]	[272..31]
gi\|119615297, gi... - gi\|56417842\|emb\|CAI22230.1\| capping protein (actin filament) muscle Z-line, beta [Homo sapiens], gi\|...	498.0	[0..2]	[272..31]
gi\|61365535, gi\|... - gi\|61365535\|gb\|AAX42723.1\| capping protein muscle Z-line beta [synthetic construct], gi\|54695808\|gb\|...	497.0	[0..1]	[272..1]
gi\|74213619 - gi\|74213619\|dbj\|BAE35614.1\| unnamed protein product [Mus musculus]	493.0	[0..1]	[272..1]
gi\|148224365, gi... - gi\|148224365\|ref\|NP_001090922.1\| F-actin capping protein subunit beta 2 [Sus scrofa], gi\|118627570\|e... gi\|1079456, gi\|4... - gi\|468204\|gb\|AAA52222.1\| actin capping protein beta subunit, isoform 2, pir\|\|A54819 actin-capping pr... gi\|197129576, gi... - gi\|224080422\|ref\|XP_002192045.1\| PREDICTED: putative actin-capping protein Z beta subunit variant 1 ...	491.0	[0..1]	[271..1]
gi\|27370869, gi\|... - gi\|27370869\|gb\|AAH41233.1\| Capzb-prov protein [Xenopus laevis], gi\|148238173\|ref\|NP_001080116.1\| cap...	490.0	[0..1]	[271..1]
gi\|41053959, gi\|... - gi\|41053959\|ref\|NP_956229.1\| capping protein (actin filament) muscle Z-line, beta [Danio rerio], gi\|...	488.0	[0..1]	[271..1]

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Predicted Domain #1

Region A:
Residues: [1-272]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDQQLDCAL DLMRRLPPQQ IEKNLSDLID LVPSLCEDLL SSVDQPLKIA RDKVVGKDYL  60
   61 LCDYNRDGDS YRSPWSNKYD PPLEDGAMPS ARLRKLEVEA NNAFDQYRDL YFEGGVSSVY 120
  121 LWDLDHGFAG VILIKKAGDG SKKIKGCWDS IHVVEVQEKS SGRTAHYKLT STVMLWLQTN 180
  181 KSGSGTMNLG GSLTRQMEKD ETVSDCSPHI ANIGRLVEDM ENKIRSTLNE IYFGKTKDIV 240
  241 NGLRSVQTFA DKSKQEALKN DLVEALKRKQ QC

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	137.0
Match:	1iznB
Description:	Capz beta-1 subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
actin binding	6.56144513012007	bayes_pls_golite062009
actin filament binding	5.39928513902709	bayes_pls_golite062009
cytoskeletal protein binding	5.10504476256679	bayes_pls_golite062009
binding	2.46279312857752	bayes_pls_golite062009
protein binding	1.31870344025745	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: