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View Structure Prediction Details

Protein: OAS1B_MOUSE
Organism: Mus musculus
Length: 251 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for OAS1B_MOUSE.

Description E-value Query
Range
Subject
Range
gi|31560524, gi|... - gi|31560524|ref|NP_035982.2| 2'-5' oligoadenylate synthetase 1G [Mus musculus], gi|21591586|gb|AAM64...
431.0 [0..1] [251..1]
gi|37901836, gi|... - gi|56541170|gb|AAH86979.1| Oas1a protein [Rattus norvegicus], gi|37901836|gb|AAP50499.1| 2'-5' oligo...
428.0 [0..1] [251..1]
OAS1_PIG - 2'-5'-oligoadenylate synthase 1 OS=Sus scrofa GN=OAS1 PE=1 SV=3
414.0 [0..3] [251..1]
gi|11272961 - gi|11272961|pir||A22842 (2'-5')oligo(A) synthetase (EC 2.7.7.-), splice form 8-2 - human
410.0 [0..3] [251..2]

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Predicted Domain #1
Region A:
Residues: [1-251]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQDLRSIPA SKLDKFIENH LPDTSFCADL REVIDALCAL LKDRSFRGPV RRMRASKGVK  60
   61 GKGTALKGRS DADLVVFLNN LTSFEDQLNQ QGVLIKEIKK QLCEVQHERR CGVKFEVHSL 120
  121 RSPNSRALSF KLSAPDLLKE VKFDVLPAYD LLDHLNILKK PNQQFYANLI SGVPAGKEGK 180
  181 LSICFMGLQK YFLNCRPTKL KRLIRLVTHW YQLCKEKLGD PLPPQYALEL LTLDAWEYGS 240
  241 RVTKFNTAQG F

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 117.0
Match: 1px5A
Description: Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.356340974097258 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.30647276733818 bayes_pls_golite062009
transferase activity 0.128557590939593 bayes_pls_golite062009
double-stranded RNA binding 0.10668512918268 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle