YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|74137533, gi\|...
Organism:	Mus musculus
Length:	277 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|74137533, gi|....

Description	E-value	Query Range	Subject Range
IMPA1_PONPY - Inositol monophosphatase - Pongo pygmaeus (Orangutan) IMPA1_PONAB - Inositol monophosphatase 1 OS=Pongo abelii GN=IMPA1 PE=2 SV=1	321.0	[0..1]	[276..1]
gi\|67971222 - gi\|67971222\|dbj\|BAE01953.1\| unnamed protein product [Macaca fascicularis]	321.0	[0..1]	[276..1]
gi\|109086796, gi... - gi\|109086798\|ref\|XP_001092711.1\| PREDICTED: inositol(myo)-1(or 4)-monophosphatase 1 isoform 2 [Macac...	321.0	[0..1]	[276..1]
IMPA1 - inositol(myo)-1(or 4)-monophosphatase 1	321.0	[0..1]	[276..1]
gi\|114620630, gi... - gi\|114620632\|ref\|XP_001168801.1\| PREDICTED: inositol(myo)-1(or 4)-monophosphatase 1 isoform 7 [Pan t...	321.0	[0..1]	[276..60]
IMPA1_MOUSE - Inositol monophosphatase 1 OS=Mus musculus GN=Impa1 PE=1 SV=1	320.0	[0..1]	[277..1]
IMPA1_RAT - Inositol monophosphatase 1 OS=Rattus norvegicus GN=Impa1 PE=1 SV=2	319.0	[0..1]	[277..1]

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Predicted Domain #1

Region A:
Residues: [1-277]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADPWQECMD YAVILARQAG EMIREALKNE MDVMIKSSPA DLVTVTDQKV EKMLMSSIKE  60
   61 KYPCHSFIGE ESVAAGEKTV FTEQPTWVID PIDGTTNFVH RFPFVAVSIG FLVNKEMEFG 120
  121 IVYSCVEDKM YTGRKGKGAF CNGQKLQVSQ QEDITKSLLV TELGSSRKPE TLRIVLSNME 180
  181 KLCSIPIHGI RSVGTAAVNM CLVATGGADA YYEMGIHCWD MAGAGIIVTE AGGVLMDVTG 240
  241 GPFDLMSRRI IAANSITLAK RIAKEIEIIP LQRDDES

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	87.69897
Match:	1imaA
Description:	Inositol monophosphatase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphatase activity	6.94859134959555	bayes_pls_golite062009
phosphoric ester hydrolase activity	6.73672244222293	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	5.8594723090245	bayes_pls_golite062009
hydrolase activity	4.43275987578288	bayes_pls_golite062009
inositol or phosphatidylinositol phosphatase activity	3.57479316466542	bayes_pls_golite062009
inositol-1(or 4)-monophosphatase activity	3.34662957972704	bayes_pls_golite062009
carbohydrate phosphatase activity	2.20066245856029	bayes_pls_golite062009
catalytic activity	2.13229228332707	bayes_pls_golite062009
fructose 1,6-bisphosphate 1-phosphatase activity	1.61382250100271	bayes_pls_golite062009
3'(2'),5'-bisphosphate nucleotidase activity	1.03636246295147	bayes_pls_golite062009
binding	0.890627780120238	bayes_pls_golite062009
protein binding	0.286223098418614	bayes_pls_golite062009
nucleotidase activity	0.191173184964385	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: