YRC Public Data Repository - Protein Structure Prediction

Protein:	NQO1_MOUSE
Organism:	Mus musculus
Length:	274 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NQO1_MOUSE.

Description	E-value	Query Range	Subject Range
NQO1_RAT - NAD(P)H dehydrogenase [quinone] 1 OS=Rattus norvegicus GN=Nqo1 PE=1 SV=4 gi\|200084, gi\|21... - gi\|2137583\|pir\|\|I52851 NAD(P)H2 dehydrogenase (quinone) (EC 1.6.99.2) 1 [similarity] - mouse, gi\|200...	277.0	[0..1]	[274..1]
gi\|1827606, gi\|1... - gi\|1827607\|pdb\|1QRD\|B Chain B, Quinone ReductaseFADCIBACRON BLUEDUROQUINONE COMPLEX, gi\|1827606\|pdb\|... NQO1_RAT - (P05982) NAD(P)H dehydrogenase [quinone] 1 (EC 1.6.5.2) (Quinone reductase 1) (NAD(P)H:quinone oxido...	274.0	[0..5]	[274..4]
gi\|13435426, gi\|... - gi\|71059897\|emb\|CAJ18492.1\| Nqo1 [Mus musculus], gi\|13435426\|gb\|AAH04579.1\| Nqo1 protein [Mus muscul...	273.0	[0..1]	[274..1]
NQO1_CAVPO - NAD(P)H dehydrogenase [quinone] 1 OS=Cavia porcellus GN=NQO1 PE=2 SV=1	268.0	[0..1]	[274..1]
gi\|77736017, gi\|... - gi\|77736017\|ref\|NP_001029707.1\| NAD(P)H dehydrogenase, quinone 1 [Bos taurus], gi\|73587441\|gb\|AAI032...	266.0	[0..1]	[274..1]
gi\|73957442 - gi\|73957442\|ref\|XP_853617.1\| PREDICTED: similar to NAD(P)H dehydrogenase [quinone] 1 (Quinone reduct...	265.0	[0..2]	[274..161]
NQO1_PONAB - NAD(P)H dehydrogenase [quinone] 1 OS=Pongo abelii GN=NQO1 PE=2 SV=1 NQO1_PONPY - NAD(P)H dehydrogenase [quinone] 1 - Pongo pygmaeus (Orangutan)	264.0	[0..1]	[274..1]
gi\|84579151 - gi\|84579151\|dbj\|BAE73009.1\| hypothetical protein [Macaca fascicularis]	258.0	[0..1]	[274..1]

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Predicted Domain #1

Region A:
Residues: [1-274]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAARRALIVL AHSEKTSFNY AMKEAAVEAL KKRGWEVLES DLYAMNFNPI ISRNDITGEL  60
   61 KDSKNFQYPS ESSLAYKEGR LSPDIVAEHK KLEAADLVIF QFPLQWFGVP AILKGWFERV 120
  121 LVAGFAYTYA AMYDNGPFQN KKTLLSITTG GSGSMYSLQG VHGDMNVILW PIQSGILRFC 180
  181 GFQVLEPQLV YSIGHTPPDA RMQILEGWKK RLETVWEETP LYFAPSSLFD LNFQAGFLMK 240
  241 KEVQEEQKKN KFGLSVGHHL GKSIPADNQI KARK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	73.69897
Match:	1qrdA
Description:	NAD(P)H:quinone reductase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein binding	1.24167506429102	bayes_pls_golite062009
binding	0.905404669218681	bayes_pls_golite062009
catalytic activity	0.275631658558537	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	0.06265719498156	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: