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View Structure Prediction Details

Protein: egr-PA
Organism: Drosophila melanogaster
Length: 415 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for egr-PA.

Description E-value Query
Range
Subject
Range
egr-PB - The gene eiger is referred to in FlyBase by the symbol Dmel\egr (CG12919, FBgn0033483). It is a prot...
gi|220951926 - gi|220951926|gb|ACL88506.1| egr-PB [synthetic construct]
387.0 [0..1] [415..1]

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Predicted Domain #1
Region A:
Residues: [1-87]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAETLKPFI TPTSANDDGF PAKATSTATA QRRTRQLIPL VLGFIGLGLV VAILALTIWQ  60
   61 TTRVSHLDKE LKSLKRVVDN LQQRLGI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [88-183]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NYLDEFDEFQ KEYENALIDY PKKVDGLTDE EDDDDGDGLD SIADDEDDDV SYSSVDDVGA  60
   61 DYEDYTDMLN KLNNAHTGTT PTSETTAEGE GETDSA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [184-415]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSASNDDNVF DDFTSYNAHK KKQERKSRSI ADVRNEEQNI QGNHTELQEK SSNEATSKES  60
   61 PAPLHHRRRM HSRHRHLLVR KGESLLSARS EDSRPAAHFH LSSRRRHQGS MGYHGDMYIG 120
  121 NDNERNSYQG HFQTRDGVLT VTNTGLYYVY AQICYNNSHD QNGFIVFQGD TPFLQCLNTV 180
  181 PTNMPHKVHT CHTSGLIHLE RNERIHLKDI HNDRNAVLRE GNNRSYFGIF KV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.0
Match: 1osgA
Description: Soluble part of TALL-1, sTALL-1 (BAFF)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 2.25413201891408 bayes_pls_golite062009
receptor binding 1.87082918048468 bayes_pls_golite062009
binding 1.55055236820725 bayes_pls_golite062009
tumor necrosis factor receptor superfamily binding 1.47525106874221 bayes_pls_golite062009
CD40 receptor binding 0.275062817872213 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle