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View Structure Prediction Details

Protein: CAP-PJ
Organism: Drosophila melanogaster
Length: 565 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CAP-PJ.

Description E-value Query
Range
Subject
Range
gi|220950558 - gi|220950558|gb|ACL87822.1| CAP-PE [synthetic construct]
CAP-PI - The gene CAP is referred to in FlyBase by the symbol Dmel\CAP (CG18408, FBgn0033504). It is a protei...
317.0 [0..8] [565..82]

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Predicted Domain #1
Region A:
Residues: [1-205]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSASTPPRRT RPSYKSNGYV SEPEPNYDSD YSTVRYRTQN PHRVQSVSSA VNVRNLNQDE  60
   61 KLYGTMPNPI KSAQNSYKNQ PGRIENYTTG HSSVSEKEKK EWWDEVMDIF NGNLEQSKLS 120
  121 PLYTEGNLSR ALAKESGYTS DSNLVFRKKE VPVSSPLSPV EQKQAYKSLQ AGGEPPLLGF 180
  181 RKPAPEKPRD LDPNAPPIPP QPPVK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [206-306]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLSSYDFPYS TDTVDGSDVN IHFKTPIRHE QRQNLSEEEL AIRQAEHMQK LYHEERRRKY  60
   61 LQELQDMNSR RHTDNFTPSQ KSPIALNRYD DFPTDVTLKS L

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [307-565]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VGPKTVARAL FNFQGQTSKE LSFRKGDTIY IRRQIDANWY EGEHNAMIGL LPASYVEIVS  60
   61 RDGARTPSKR PSEGQARAKY NFQAQSGIEL SLNKGELVTL TRRVDGNWFE GKIANRKGIF 120
  121 PCSYVEVLTD IGAEDIAART TTVITSQSTT NLRPNLDVLR TNINNEFNTL TQNGAQPPNG 180
  181 ILKETRTLHK TDALHVDTSS EPLAYRALYK YRPQNSDELE LLEGDVVHVL EKCDDGWFVG 240
  241 TSQRTGCFGT FPGNYVERA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.522879
Match: 1griA
Description: Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains; Growth factor receptor-bound protein 2 (GRB2)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.13376047180398 bayes_pls_golite062009
protein binding 1.03382488697656 bayes_pls_golite062009
signal transducer activity 0.69727426993974 bayes_pls_golite062009
molecular transducer activity 0.69727426993974 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle