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View Structure Prediction Details

Protein: cactin-PA
Organism: Drosophila melanogaster
Length: 762 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cactin-PA.

Description E-value Query
Range
Subject
Range
gi|3253120, gi|7... - pir||T02672 hypothetical protein R31449_3 - human (fragment), gi|3253120|gb|AAC24305.1| R31449_3 [H...
398.0 [0..157] [762..20]

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Predicted Domain #1
Region A:
Residues: [1-79]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLISIALLQL LVAIWVGFLH LATLALFIFY FTSFIPKNSL KKMPKEKSKH RHRSRSRERR  60
   61 DHRSPDPRSS RNRDRDRER

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.15
Match: 2h8aA
Description: No description for 2h8aA was found.

Predicted functions:

Term Confidence Notes
binding 0.56838161166777 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [80-514]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EREKDRDHRD HRDKERDQRR EREKDKSRDK KREHKSRRRR SSSSSSSPSS STSSSVPGAP  60
   61 RSPLVKSPMK LLQTLEARRL VEQKDRQRKK EELKAHETPE EKRARRLREK QAKEQRRRER 120
  121 MGWDNEYQTY SNEDNPFGDS NLTSTFHWGK KLEVEGLSNL STKTVEVLSL QKQLENRREL 180
  181 EKVKKRRQER ELERQVREDD LMMQQRAKEA VQFREWQRQE DQFHLEQARL RSEIRIRDGR 240
  241 AKPIDLLAQY VAAGNEPLEE CLEMQMHEPY VLLNGLPVEE LEDLLVDIKV YEELEQGKHI 300
  301 DFWNDMITIV QDELQRQQKL EAENSSLNQR RDGIHQAVVK DVADIFRGKN AQQLEEMRHR 360
  361 IEAKISGRAD GVDISYWESL LSQLKAHMAR ARLRDRHQAL LREKLSLLKR ENDNETLQEK 420
  421 VAPQVKEEEM ETQDA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.69897
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [515-603]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDPEVEEGSP EDEEDPLNEL RKTVRLYQAG NYSPRYIREE DFTGRRAQNE DVDEPEAEGL  60
   61 LYEEEDDERR TQRQRLLILH PERVDNNQL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [604-762]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPQELRMRNE AKQGMQGDEA EFSVETTLDA VPQLATDKYR PRKPRYFNRV HTGFEWNKYN  60
   61 QTHYDMDNPP PKIVQGYKFN IFYPDLMDKS QTPQYFLTPC ADNGDFAVLR FHTGPPYEDI 120
  121 AFKIVNREWE FSYKRGFRCQ FHNNIFQLWF HFKRYRYRR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle