YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|44680105
Organism:	Homo sapiens
Length:	793 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|44680105.

Description	E-value	Query Range	Subject Range
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1	2.0E-75	[1..785]	[842..1621]
MYH4_MOUSE - Myosin-4 OS=Mus musculus GN=Myh4 PE=2 SV=1	4.0E-75	[1..785]	[844..1623]
MYH4_RAT - Myosin-4 OS=Rattus norvegicus GN=Myh4 PE=1 SV=1	9.0E-75	[1..785]	[844..1623]
gi\|73955720 - gi\|73955720\|ref\|XP_861233.1\| PREDICTED: similar to Myosin heavy chain, skeletal muscle, perinatal (M...	9.0E-75	[1..785]	[734..1513]
MYH2_BOVIN - Myosin-2 OS=Bos taurus GN=MYH2 PE=2 SV=1	2.0E-74	[1..785]	[845..1627]

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Predicted Domain #1

Region A:
Residues: [1-299]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDFERRREL RRQKREEMRL EAERIAYQRN DDDEEEAARE RRRRARQERL RQKQEEESLG  60
   61 QVTDQVEVNA QNSVPDEEAK TTTTNTQVEG DDEAAFLERL ARREERRQKR LQEALERQKE 120
  121 FDPTITDASL SLPSRRMQND TAENETTEKE EKSESRQERY EIEETETVTK SYQKNDWRDA 180
  181 EENKKEDKEK EEEEEEKPKR GSIGENQVEV MVEEKTTESQ EETVVMSLKN GQISSEEPKQ 240
  241 EEEREQGSDE ISHHEKMEEE DKERAEAERA RLEAEERERI KAEQDKKIAD ERARIEAEE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	12.09691
Match:	1i84S
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [300-495]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KAAAQERERR EAEERERMRE EEKRAAEERQ RIKEEEKRAA EERQRIKEEE KRAAEERQRI  60
   61 KEEEKRAAEE RQRARAEEEE KAKVEEQKRN KQLEEKKHAM QETKIKGEKV EQKIEGKWVN 120
  121 EKKAQEDKLQ TAVLKKQGEE KGTKVQAKRE KLQEDKPTFK KEEIKDEKIK KDKEPKEEVK 180
  181 SFMDRKKGFT EVKSQN

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.8
Match:	1jchA
Description:	Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [496-793]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEFMTHKLKH TENTFSRPGG RASVDTKEAE GAPQVEAGKR LEELRRRRGE TESEEFEKLK  60
   61 QKQQEAALEL EELKKKREER RKVLEEEEQR RKQEEADRKL REEEEKRRLK EEIERRRAEA 120
  121 AEKRQKMPED GLSDDKKPFK CFTPKGSSLK IEERAEFLNK SVQKSSGVKS THQAAIVSKI 180
  181 DSRLEQYTSA IEGTKSAKPT KPAASDLPVP AEGVRNIKSM WEKGNVFSSP TAAGTPNKET 240
  241 AGLKVGVSSR INEWLTKTPD GNKSPAPKPS DLRPGDVSSK RNLWEKQSVD KVTSPTKV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	8.39794
Match:	1c1gA
Description:	Tropomyosin
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits