YRC Public Data Repository - Protein Structure Prediction

Protein:	LRFN2
Organism:	Homo sapiens
Length:	789 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LRFN2.

Description	E-value	Query Range	Subject Range
gi\|6330833 - gi\|6330833\|dbj\|BAA86560.1\| KIAA1246 protein [Homo sapiens]	0.0	[1..789]	[44..832]
LRFN2_MACFA - Leucine-rich repeat and fibronectin type-III domain-containing protein 2 OS=Macaca fascicularis GN=L...	0.0	[1..789]	[1..789]
gi\|12856914, gi\|... - gi\|58037213\|ref\|NP_081728.1\| leucine rich repeat and fibronectin type III domain containing 2 [Mus m...	0.0	[1..789]	[1..788]
gi\|161760638, gi... - gi\|161760638\|ref\|NP_001034788.1\| leucine rich repeat and fibronectin type III domain containing 2 [R...	0.0	[1..789]	[1..788]
gi\|73972801 - gi\|73972801\|ref\|XP_538906.2\| PREDICTED: similar to leucine rich repeat and fibronectin type III doma...	0.0	[1..789]	[31..822]
gi\|109071047 - gi\|109071047\|ref\|XP_001114127.1\| PREDICTED: similar to leucine rich repeat and fibronectin type III ...	4.0E-99	[1..789]	[815..1566]
gi\|114677152 - gi\|114677152\|ref\|XP_512991.2\| PREDICTED: similar to leucine rich repeat and fibronectin type III dom...	3.0E-93	[21..789]	[34..771]

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Predicted Domain #1

Region A:
Residues: [1-517]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METLLGGLLA FGMAFAVVDA CPKYCVCQNL SESLGTLCPS KGLLFVPPDI DRRTVELRLG  60
   61 GNFIIHISRQ DFANMTGLVD LTLSRNTISH IQPFSFLDLE SLRSLHLDSN RLPSLGEDTL 120
  121 RGLVNLQHLI VNNNQLGGIA DEAFEDFLLT LEDLDLSYNN LHGLPWDSVR RMVNLHQLSL 180
  181 DHNLLDHIAE GTFADLQKLA RLDLTSNRLQ KLPPDPIFAR SQASALTATP FAPPLSFSFG 240
  241 GNPLHCNCEL LWLRRLERDD DLETCGSPGG LKGRYFWHVR EEEFVCEPPL ITQHTHKLLV 300
  301 LEGQAATLKC KAIGDPSPLI HWVAPDDRLV GNSSRTAVYD NGTLDIFITT SQDSGAFTCI 360
  361 AANAAGEATA MVEVSIVQLP HLSNSTSRTA PPKSRLSDIT GSSKTSRGGG GSGGGEPPKS 420
  421 PPERAVLVSE VTTTSALVKW SVSKSAPRVK MYQLQYNCSD DEVLIYRMIP ASNKAFVVNN 480
  481 LVSGTGYDLC VLAMWDDTAT TLTATNIVGC AQFFTKA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.522879
Match:	2id5A
Description:	No description for 2id5A was found.

Predicted Domain #2

Region A:
Residues: [518-789]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DYPQCQSMHS QILGGTMILV IGGIIVATLL VFIVILMVRY KVCNHEAPSK MAAAVSNVYS  60
   61 QTNGAQPPPP SSAPAGAPPQ GPPKVVVRNE LLDFTASLAR ASDSSSSSSL GSGEAAGLGR 120
  121 APWRIPPSAP RPKPSLDRLM GAFASLDLKS QRKEELLDSR TPAGRGAGTS ARGHHSDREP 180
  181 LLGPPAARAR SLLPLPLEGK AKRSHSFDMG DFAAAAAGGV VPGGYSPPRK VSNIWTKRSL 240
  241 SVNGMLLPFE ESDLVGARGT FGSSEWVMES TV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	17.522879
Match:	1fnhA
Description:	Fibronectin, different Fn3 modules
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits