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View Structure Prediction Details

Protein: C9orf72
Organism: Homo sapiens
Length: 481 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for C9orf72.

Description E-value Query
Range
Subject
Range
gi|123229922, gi... - gi|94373145|ref|XP_986526.1| PREDICTED: similar to Protein C9orf72 homolog isoform 4 [Mus musculus],...
0.0 [1..481] [1..481]
CI072_RAT - Protein C9orf72 homolog OS=Rattus norvegicus PE=2 SV=1
0.0 [1..481] [1..481]
gi|114624009, gi... - gi|114624009|ref|XP_001155133.1| PREDICTED: hypothetical protein isoform 3 [Pan troglodytes], gi|114...
0.0 [1..481] [1..481]
CCDS6522.1_1 - null
gi|109111311 - gi|109111311|ref|XP_001104667.1| PREDICTED: similar to Protein C9orf72 homolog [Macaca mulatta]
0.0 [1..481] [1..481]
gi|156718106, gi... - gi|76624134|ref|XP_869915.1| PREDICTED: similar to Protein C9orf72 homolog isoform 2 [Bos taurus], g...
0.0 [1..481] [1..481]
gi|73971093, gi|... - gi|73971099|ref|XP_538691.2| PREDICTED: similar to Protein C9orf72 homolog isoform 1 [Canis familiar...
0.0 [1..481] [1..481]
gi|220679138, gi... - gi|45387633|ref|NP_991166.1| hypothetical protein LOC402895 [Danio rerio], gi|37595336|gb|AAQ94554.1...
0.0 [1..481] [1..462]

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Predicted Domain #1
Region A:
Residues: [1-76]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTLCPPPSP AVAKTEIALS GKSPLLAATF AYWDNILGPR VRHIWAPKTE QVLLSDGEIT  60
   61 FLANHTLNGE ILRNAE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [77-169]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGAIDVKFFV LSEKGVIIVS LIFDGNWNGD RSTYGLSIIL PQTELSFYLP LHRVCVDRLT  60
   61 HIIRKGRIWM HKERQENVQK IILEGTERME DQG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [170-316]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QSIIPMLTGE VIPVMELLSS MKSHSVPEEI DIADTVLNDD DIGDSCHEGF LLNAISSHLQ  60
   61 TCGCSVVVGS SAEKVNKIVR TLCLFLTPAE RKCSRLCEAE SSFKYESGLF VQGLLKDSTG 120
  121 SFVLPFRQVM YAPYPTTHID VDVNTVK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.543 d.68.3 SirA-like
View Download 0.499 c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.425 a.4.5 "Winged helix" DNA-binding domain
View Download 0.391 a.28.2 Colicin E immunity proteins
View Download 0.387 a.4.12 TrpR-like

Predicted Domain #4
Region A:
Residues: [317-481]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QMPPCHEHIY NQRRYMRSEL TAFWRATSEE DMAQDTIIYT DESFTPDLNI FQDVLHRDTL  60
   61 VKAFLDQVFQ LKPGLSLRST FLAQFLLVLH RKALTLIKYI EDDTQKGKKP FKSLRNLKID 120
  121 LDLTAEGDLN IIMALAEKIK PGLHSFIFGR PFYTSVQERD VLMTF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle