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View Structure Prediction Details

Protein: ASPSCR1
Organism: Homo sapiens
Length: 553 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ASPSCR1.

Description E-value Query
Range
Subject
Range
gi|123983414, gi... - gi|123998117|gb|ABM86660.1| alveolar soft part sarcoma chromosome region, candidate 1 [synthetic con...
gi|17511732, gi|... - gi|17511732|gb|AAH18722.1| Alveolar soft part sarcoma chromosome region, candidate 1 [Homo sapiens],...
0.0 [12..553] [12..553]
ASPC1_MOUSE - Tether containing UBX domain for GLUT4 OS=Mus musculus GN=Aspscr1 PE=1 SV=1
0.0 [12..553] [12..550]
gi|114671054 - gi|114671054|ref|XP_001166432.1| PREDICTED: similar to alveolar soft part sarcoma chromosome region,...
0.0 [35..553] [32..550]
gi|109492391 - gi|109492391|ref|XP_001081837.1| PREDICTED: similar to alveolar soft part sarcoma chromosome region,...
0.0 [12..553] [12..551]
gi|73964675 - gi|73964675|ref|XP_533134.2| PREDICTED: similar to alveolar soft part sarcoma chromosome region, can...
0.0 [1..553] [1..544]

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Predicted Domain #1
Region A:
Residues: [1-86]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAPAGGGGS AVSVLAPNGR RHTVKVTPST VLLQVLEDTC RRQDFNPCEY DLKFQRSVLD  60
   61 LSLQWRFANL PNNAKLEMVP ASRSRE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.0
Match: 2al3A
Description: No description for 2al3A was found.

Predicted functions:

Term Confidence Notes
binding 0.0934358341245259 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [87-193]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GPENMVRIAL QLDDGSRLQD SFCSGQTLWE LLSHFPQIRE CLQHPGGATP VCVYTRDEVT  60
   61 GEAALRGTTL QSLGLTGGSA TIRFVMKCYD PVGKTPGSLG SSASAGQ

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.959
Match: 2cr5A
Description: The deposition and citation title is: Solution structure of the UBX domain of D0H8S2298E protein
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [194-336]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAASAPLPLE SGELSRGDLS RPEDADTSGP CCEHTQEKQS TRAPAAAPFV PFSGGGQRLG  60
   61 GPPGPTRPLT SSSAKLPKSL SSPGGPSKPK KSKSGQDPQQ EQEQERERDP QQEQERERPV 120
  121 DREPVDREPV VCHPDLEERL QAW

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [337-476]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PAELPDEFFE LTVDDVRRRL AQLKSERKRL EEAPLVTKAF REAQIKEKLE RYPKVALRVL  60
   61 FPDRYVLQGF FRPSETVGDL RDFVRSHLGN PELSFYLFIT PPKTVLDDHT QTLFQANLFP 120
  121 AALVHLGAEE PAGVYLEPGL 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.30103
Match: 1s3sG
Description: Crystal structure of AAA ATPase p97/VCP ND1 in complex with p47 C
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [477-553]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEHAISPSAA DVLVARYMSR AAGSPSPLPA PDPAPKSEPA AEEGALVPPE PIPGTAQPVK  60
   61 RSLGKVPKWL KLPASKR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.828 0.353 membrane a.77.1 DEATH domain


YRC Informatics Platform - Version 3.0
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