| Protein: | gi|306841 |
| Organism: | Homo sapiens |
| Length: | 1342 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|306841.
| Description | E-value | Query Range |
Subject Range |
|
|
856.0 | [0..1] | [1342..1] |
|
|
855.0 | [0..1] | [1342..1] |
|
|
855.0 | [0..1] | [1342..1] |
|
|
844.0 | [0..1] | [1342..1] |
|
|
838.0 | [0..1] | [1341..1] |
|
|
826.0 | [0..1] | [1342..206] |
|
|
815.0 | [0..1] | [1342..1] |
|
Region A: Residues: [1-667] |
1 11 21 31 41 51
| | | | | |
1 MRANDALQVL GLLFSLARGS EVGNSQAVCP GTLNGLSVTG DAENQYQTLY KLYERCEVVM 60
61 GNLEIVLTGH NADLSFLQWI REVTGYVLVA MNEFSTLPLP NLRVVRGTQV YDGKFAIFVM 120
121 LNYNTNSSHA LRQLRLTQLT EILSGGVYIE KNDKLCHMDT IDWRDIVRDR DAEIVVKDNG 180
181 RSCPPCHEVC KGRCWGPGSE DCQTLTKTIC APQCNGHCFG PNPNQCCHDE CAGGCSGPQD 240
241 TDCFACRHFN DSGACVPRCP QPLVYNKLTF QLEPNPHTKY QYGGVCVASC PHNFVVDQTS 300
301 CVRACPPDKM EVDKNGLKMC EPCGGLCPKA CEGTGSGSRF QTVDSSNIDG FVNCTKILGN 360
361 LDFLITGLNG DPWHKIPALD PEKLNVFRTV REITGYLNIQ SWPPHMHNFS VFSNLTTIGG 420
421 RSLYNRGFSL LIMKNLNVTS LGFRSLKEIS AGRIYISANR QLCYHHSLNW TKVLRGPTEE 480
481 RLDIKHNRPR RDCVAEGKVC DPLCSSGGCW GPGPGQCLSC RNYSRGGVCV THCNFLNGEP 540
541 REFAHEAECF SCHPECQPMG GTATCNGSGS DTCAQCAHFR DGPHCVSSCP HGVLGAKGPI 600
601 YKYPDVQNEC RPCHENCTQG CKGPELQDCL GQTLVLIGKT HLTMALTVIA GLVVIFMMLG 660
661 GTFLYWR
|
| Detection Method: |  |
| Confidence: | 121.0 |
| Match: | 1m6bA |
| Description: | Receptor protein-tyrosine kinase Erbb-3 extracellular domain; Receptor protein-tyrosine kinase Erbb-3 Cys-rich domains |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [668-1031] |
1 11 21 31 41 51
| | | | | |
1 GRRIQNKRAM RRYLERGESI EPLDPSEKAN KVLARIFKET ELRKLKVLGS GVFGTVHKGV 60
61 WIPEGESIKI PVCIKVIEDK SGRQSFQAVT DHMLAIGSLD HAHIVRLLGL CPGSSLQLVT 120
121 QYLPLGSLLD HVRQHRGALG PQLLLNWGVQ IAKGMYYLEE HGMVHRNLAA RNVLLKSPSQ 180
181 VQVADFGVAD LLPPDDKQLL YSEAKTPIKW MALESIHFGK YTHQSDVWSY GVTVWELMTF 240
241 GAEPYAGLRL AEVPDLLEKG ERLAQPQICT IDVYMVMVKC WMIDENIRPT FKELANEFTR 300
301 MARDPPRYLV IKRESGPGIA PGPEPHGLTN KKLEEVELEP ELDLDLDLEA EEDNLATTTL 360
361 GSAL
|
| Detection Method: | |
| Confidence: | 50.0 |
| Match: | 1xkkA |
| Description: | EGFR kinase domain complexed with a quinazoline inhibitor- GW572016 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1032-1123] |
1 11 21 31 41 51
| | | | | |
1 SLPVGTLNRP RGSQSLLSPS SGYMPMNQGN LGGSCQESAV SGSSERCPRP VSLHPMPRGC 60
61 LASESSEGHV TGSEAELQEK VSMCRSRSRS RS
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1124-1342] |
1 11 21 31 41 51
| | | | | |
1 PRPRGDSAYH SQRHSLLTPV TPLSPPGLEE EDVNGYVMPD THLKGTPSSR EGTLSSVGLS 60
61 SVLGTEEEDE DEEYEYMNRR RRHSPPHPPR PSSLEELGYE YMDVGSDLSA SLGSTQSCPL 120
121 HPVPIMPTAG TTPDEDYEYM NRQRDGGGPG GDYAAMGACP ASEQGYEEMR AFQGPGHQAP 180
181 HVHYARLKTL RSLEATDSAF DNPDYWHSRL FPKANAQRT
|
| Detection Method: | |
| Confidence: | 4.30103 |
| Match: | 1y0fA |
| Description: | No description for 1y0fA was found. |
