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View Structure Prediction Details

Protein: NAA25
Organism: Homo sapiens
Length: 972 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NAA25.

Description E-value Query
Range
Subject
Range
gi|33235594 - gi|33235594|dbj|BAC80174.1| P120 [Homo sapiens]
0.0 [1..972] [1..972]
gi|114647008 - gi|114647008|ref|XP_509384.2| PREDICTED: hypothetical protein isoform 2 [Pan troglodytes]
0.0 [1..972] [1..972]
gi|55742803 - ref|NP_766310.2| RIKEN cDNA C330023M02 [Mus musculus]
NAA25_MOUSE - N-alpha-acetyltransferase 25, NatB auxiliary subunit OS=Mus musculus GN=Naa25 PE=1 SV=1
0.0 [1..972] [1..972]
gi|57105852 - gi|57105852|ref|XP_543400.1| PREDICTED: similar to CG4845-PA isoform 1 [Canis familiaris]
0.0 [1..972] [1..972]
NAA25_RAT - N-alpha-acetyltransferase 25, NatB auxiliary subunit OS=Rattus norvegicus GN=Naa25 PE=2 SV=1
0.0 [1..932] [1..932]
gi|76639243 - gi|76639243|ref|XP_869182.1| PREDICTED: similar to CG4845-PA [Bos taurus]
0.0 [476..972] [1..497]

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Predicted Domain #1
Region A:
Residues: [1-223]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATRGHVQDP NDRRLRPIYD YLDNGNNKMA IQQADKLLKK HKDLHCAKVL KAIGLQRTGK  60
   61 QEEAFTLAQE VAALEPTDDN SLQALTILYR EMHRPELVTK LYEAAVKKVP NSEEYHSHLF 120
  121 MAYARVGEYK KMQQAGMALY KIVPKNPYYF WSVMSLIMQS ISAQDENLSK TMFLPLAERM 180
  181 VEKMVKEDKI EAEAEVELYY MILERLGKYQ EALDVIRGKL GEK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.09691
Match: 1w3bA
Description: The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.02652482814057 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [224-650]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LTSEIQSREN KCMAMYKKLS RWPECNALSR RLLLKNSDDW QFYLTYFDSV FRLIEEAWSP  60
   61 PAEGEHSLEG EVHYSAEKAV KFIEDRITEE SKSSRHLRGP HLAKLELIRR LRSQGCNDEY 120
  121 KLGDPEELMF QYFKKFGDKP CCFTDLKVFV DLLPATQCTK FINQLLGVVP LSTPTEDKLA 180
  181 LPADIRALQQ HLCVVQLTRL LGLYHTMDKN QKLSVVRELM LRYQHGLEFG KTCLKTELQF 240
  241 SDYYCLLAVH ALIDVWRETG DETTVWQALT LLEEGLTHSP SNAQFKLLLV RIYCMLGAFE 300
  301 PVVDLYSSLD AKHIQHDTIG YLLTRYAESL GQYAAASQSC NFALRFFHSN QKDTSEYIIQ 360
  361 AYKYGAFEKI PEFIAFRNRL NNSLHFAQVR TERMLLDLLL EANISTSLAE SIKSMNLRPE 420
  421 EDDIPWE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.0
Match: 2ooeA
Description: No description for 2ooeA was found.

Predicted functions:

Term Confidence Notes
binding 0.02652482814057 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [651-752]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DLRDNRDLNV FFSWDPKDRD VSEEHKKLSL EEETLWLRIR SLTLRLISGL PSLNHPVEPK  60
   61 NSEKTAENGV SSRIDILRLL LQQLEATLET GKRFIEKDIQ YP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [753-972]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FLGPVPTRMG GFFNSGCSQC QISSFYLVND IYELDTSGLE DTMEIQERIE NSFKSLLDQL  60
   61 KDVFSKCKGD LLEVKDGNLK THPTLLENLV FFVETISVIL WVSSYCESVL RPYKLNLQKK 120
  121 KKKKKETSII MPPVFTSFQD YVTGLQTLIS NVVDHIKGLE THLIALKLEE LILEDTSLSP 180
  181 EERKFSKTVQ GKVQSSYLHS LLEMGELLKK RLETTKKLKI 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle