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View Structure Prediction Details

Protein: INSIG1
Organism: Homo sapiens
Length: 277 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for INSIG1.

Description E-value Query
Range
Subject
Range
gi|61373033, gi|... - gi|61373038|gb|AAX43962.1| insulin induced gene 1 [synthetic construct], gi|61373033|gb|AAX43961.1| ...
414.0 [0..1] [277..1]
gi|114616928, gi... - gi|114616928|ref|XP_001145726.1| PREDICTED: insulin induced gene 1 isoform 5 [Pan troglodytes], gi|1...
410.0 [0..1] [277..1]
gi|2358269 - gi|2358269|gb|AAB69121.1| insulin induced protein 1 [Homo sapiens]
409.0 [0..1] [277..1]
INSI1_MOUSE - Insulin-induced gene 1 protein OS=Mus musculus GN=Insig1 PE=2 SV=1
357.0 [0..1] [277..1]
INSI1_CRIGR - Insulin-induced gene 1 protein OS=Cricetulus griseus GN=INSIG1 PE=2 SV=1
341.0 [0..1] [277..1]

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Predicted Domain #1
Region A:
Residues: [1-78]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPRLHDHFWS CSCAHSARRR GPPRASAAGL AAKVGEMINV SVSGPSLLAA HGAPDADPAP  60
   61 RGRSAAMSGP EPGSPYPN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.585 a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.463 d.95.2 Homing endonucleases
View Download 0.448 d.50.1 dsRNA-binding domain-like
View Download 0.443 a.4.1 Homeodomain-like
View Download 0.443 a.64.1 Saposin

Predicted Domain #2
Region A:
Residues: [79-277]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TWHHRLLQRS LVLFSVGVVL ALVLNLLQIQ RNVTLFPEEV IATIFSSAWW VPPCCGTAAA  60
   61 VVGLLYPCID SHLGEPHKFK REWASVMRCI AVFVGINHAS AKLDFANNVQ LSLTLAALSL 120
  121 GLWWTFDRSR SGLGLGITIA FLATLITQFL VYNGVYQYTS PDFLYIRSWL PCIFFSGGVT 180
  181 VGNIGRQLAM GVPEKPHSD

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 140.455932
Match: PF07281.3
Description: No description for PF07281.3 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


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Created and Maintained by: Michael Riffle