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View Structure Prediction Details

Protein: gi|31880783
Organism: Homo sapiens
Length: 385 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|31880783.

Description E-value Query
Range
Subject
Range
PELO - pelota homolog (Drosophila)
gi|123989284, gi... - gi|123999236|gb|ABM87197.1| pelota homolog (Drosophila) [synthetic construct], gi|123989284|gb|ABM83...
0.0 [1..385] [1..385]
PELO_BOVIN - (Q58DV0) Protein pelota homolog
0.0 [1..385] [1..385]
PELO_PONPY - Protein pelota homolog - Pongo pygmaeus (Orangutan)
PELO_PONAB - Protein pelota homolog OS=Pongo abelii GN=PELO PE=2 SV=1
0.0 [1..385] [1..385]
PELO_RAT - Protein pelota homolog OS=Rattus norvegicus GN=Pelo PE=1 SV=1
0.0 [1..385] [1..385]
PELO_MOUSE - Protein pelota homolog OS=Mus musculus GN=Pelo PE=2 SV=2
0.0 [1..385] [1..385]
gi|73954250 - gi|73954250|ref|XP_536477.2| PREDICTED: similar to Pelota homolog [Canis familiaris]
0.0 [5..385] [52..432]

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Predicted Domain #1
Region A:
Residues: [1-117]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLVRKNIEK DNAGQVTLVP EEPEDMWHTY NLVQVGDSLR ASTIRKVQTE SSTGSVGSNR  60
   61 VRTTLTLCVE AIDFDSQACQ LRVKGTNIQE NEYVKMGAYH TIELEPNRQF TLAKKQW

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.82
Match: 2qi2A
Description: No description for 2qi2A was found.

Predicted Domain #2
Region A:
Residues: [118-275]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSVVLERIEQ ACDPAWSADV AAVVMQEGLA HICLVTPSMT LTRAKVEVNI PRKRKGNCSQ  60
   61 HDRALERFYE QVVQAIQRHI HFDVVKCILV ASPGFVREQF CDYLFQQAVK TDNKLLLENR 120
  121 SKFLQVHASS GHKYSLKEAL CDPTVASRLS DTKAAGEV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.39794
Match: 2hstA
Description: No description for 2hstA was found.

Predicted Domain #3
Region A:
Residues: [276-385]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KALDDFYKML QHEPDRAFYG LKQVEKANEA MAIDTLLISD ELFRHQDVAT RSRYVRLVDS  60
   61 VKENAGTVRI FSSLHVSGEQ LSQLTGVAAI LRFPVPELSD QEGDSSSEED 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.522879
Match: 1x52A
Description: Solution structures of the C-terminal domain of the human Pelota homolog (CGI-17)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 3.8176240743328 bayes_pls_golite062009
structural constituent of ribosome 2.50763528378297 bayes_pls_golite062009
nucleic acid binding 2.47457449347285 bayes_pls_golite062009
binding 2.34187530323842 bayes_pls_golite062009
structural molecule activity 2.17996532926344 bayes_pls_golite062009
mRNA binding 1.38466459724533 bayes_pls_golite062009
1.36644447800624 bayes_pls_golite062009
translation release factor activity 0.481117366173015 bayes_pls_golite062009
translation termination factor activity 0.454816016731369 bayes_pls_golite062009
protein binding 0.381324299701367 bayes_pls_golite062009
catalytic activity 0.264002643439785 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle