YRC Public Data Repository - Protein Structure Prediction

Protein:	NUP85
Organism:	Homo sapiens
Length:	656 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NUP85.

Description	E-value	Query Range	Subject Range
gi\|10434102 - gi\|10434102\|dbj\|BAB14130.1\| unnamed protein product [Homo sapiens]	0.0	[1..656]	[1..656]
gi\|114670417 - gi\|114670417\|ref\|XP_511672.2\| PREDICTED: nucleoporin 85 [Pan troglodytes]	0.0	[1..656]	[1..656]
NUP85_MOUSE - Nuclear pore complex protein Nup85 OS=Mus musculus GN=Nup85 PE=1 SV=1	0.0	[1..656]	[1..656]
NUP85_RAT - Nuclear pore complex protein Nup85 OS=Rattus norvegicus GN=Nup85 PE=2 SV=1	0.0	[1..656]	[1..656]
gi\|73964916 - gi\|73964916\|ref\|XP_533121.2\| PREDICTED: similar to pericentrin 1 isoform 1 [Canis familiaris]	0.0	[1..656]	[1..655]
NUP85_BOVIN - Nuclear pore complex protein Nup85 OS=Bos taurus GN=NUP85 PE=2 SV=1	0.0	[1..656]	[1..656]
gi\|53134610, gi\|... - gi\|57530216\|ref\|NP_001006426.1\| nucleoporin 85 [Gallus gallus], gi\|53134610\|emb\|CAG32347.1\| hypothet...	0.0	[1..656]	[1..674]
NUP85_XENLA - Nuclear pore complex protein Nup85 OS=Xenopus laevis GN=nup85 PE=2 SV=1	0.0	[1..654]	[1..652]

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Predicted Domain #1

Region A:
Residues: [1-94]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEELDGEPTV TLIPGVNSKK NQMYFDWGPG EMLVCETSFN KKEKSEMVPS CPFIYIIRKD  60
   61 VDVYSQILRK LFNESHGIFL GLQRIDEELT GKSR

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [95-656]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSQLVRVSKN YRSVIRACME EMHQVAIAAK DPANGRQFSS QVSILSAMEL IWNLCEILFI  60
   61 EVAPAGPLLL HLLDWVRLHV CEVDSLSADV LGSENPSKHD SFWNLVTILV LQGRLDEARQ 120
  121 MLSKEADASP ASAGICRIMG DLMRTMPILS PGNTQTLTEL ELKWQHWHEE CERYLQDSTF 180
  181 ATSPHLESLL KIMLGDEAAL LEQKELLSNW YHFLVTRLLY SNPTVKPIDL HYYAQSSLDL 240
  241 FLGGESSPEP LDNILLAAFE FDIHQVIKEC SIALSNWWFV AHLTDLLDHC KLLQSHNLYF 300
  301 GSNMREFLLL EYASGLFAHP SLWQLGVDYF DYCPELGRVS LELHIERIPL NTEQKALKVL 360
  361 RICEQRQMTE QVRSICKILA MKAVRNNRLG SALSWSIRAK DAAFATLVSD RFLRDYCERG 420
  421 CFSDLDLIDN LGPAMMLSDR LTFLGKYREF HRMYGEKRFA DAASLLLSLM TSRIAPRSFW 480
  481 MTLLTDALPL LEQKQVIFSA EQTYELMRCL EDLTSRRPVH GESDTEQLQD DDIETTKVEM 540
  541 LRLSLARNLA RAIIREGSLE GS

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.18
Match:	2qx5A
Description:	No description for 2qx5A was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits