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View Structure Prediction Details

Protein: gi|25453474, gi|...
Organism: Homo sapiens
Length: 647 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|25453474, gi|....

Description E-value Query
Range
Subject
Range
gi|60653293, gi|... - gi|60653293|gb|AAX29341.1| eukaryotic translation elongation factor 1 delta [synthetic construct], g...
1093.0 [0..1] [647..1]
gi|60656347 - gi|60656347|gb|AAX32737.1| eukaryotic translation elongation factor 1 delta [synthetic construct]
gi|119602639, gi... - gi|30583323|gb|AAP35906.1| eukaryotic translation elongation factor 1 delta (guanine nucleotide exch...
1092.0 [0..1] [647..1]
gi|114622300 - gi|114622300|ref|XP_519999.2| PREDICTED: eukaryotic translation elongation factor 1 delta [Pan trogl...
1084.0 [0..1] [647..1]
gi|67972082, gi|... - gi|67972082|dbj|BAE02383.1| unnamed protein product [Macaca fascicularis], gi|67969825|dbj|BAE01260....
1031.0 [0..1] [647..1]
gi|51259466, gi|... - gi|61556967|ref|NP_001013122.1| eukaryotic translation elongation factor 1 delta [Rattus norvegicus]...
1026.0 [0..1] [647..1]
gi|51262090, gi|... - gi|56699438|ref|NP_083939.1| eukaryotic translation elongation factor 1 delta isoform a [Mus musculu...
996.0 [0..1] [647..1]
gi|76634024 - gi|76634024|ref|XP_884674.1| PREDICTED: similar to eukaryotic translation elongation factor 1 delta ...
902.0 [0..1] [647..1]

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Predicted Domain #1
Region A:
Residues: [1-182]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRSGKASCTL ETVWEDKHKY EEAERRFYEH EATQAAASAQ QLPAEGPAMN GPGQDDPEDA  60
   61 DEAEAPDGGS RRDPRKSQDS RKPLQKKRKR SPKSGLGPAD LALLGLSAER VWLDKSLFDQ 120
  121 AESSYRQKLA DVAAQAAWPP ALAPWGLCTH GNQVACHHVT WGIWVNKSSF DQAERAFVEW 180
  181 SQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [183-402]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ALLLAPDGSR RQGTPNTGQQ VAVPDLAHQP SPPVNGQPPL GSLQALVREV WLEKPRYDAA  60
   61 ERGFYEALFD GHPPGKVRLQ ERAGLAEGAR RGRRDRRGRN ILGNKRAGLR RADGEAPSAL 120
  121 PYCYFLQKDA EAPWLSKPAY DSAECRHHAA EALRVAWCLE AASLSHRPGP RSGLSVSSLR 180
  181 PNRKMATNFL AHEKIWFDKF KYDDAERRFY EQMNGPVAGA 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [403-505]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRQENGASVI LRDIARAREN IQKSLAGSSG PGASSGTSGD HGELVVRIAS LEVENQSLRG  60
   61 VVQELQQAIS KLEARLNVLE KSSPGHRATA PQTQHVSPMR QVE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.718 N/A N/A a.216.1 Description not found.
View Download 0.613 N/A N/A a.29.9 Description not found.
View Download 0.590 N/A N/A a.29.16 Description not found.
View Download 0.572 N/A N/A a.25.1 Ferritin-like
View Download 0.569 N/A N/A a.29.13 Description not found.
View Download 0.459 N/A N/A a.25.1 Ferritin-like
View Download 0.398 N/A N/A a.25.1 Ferritin-like
View Download 0.392 N/A N/A a.25.1 Ferritin-like
View Download 0.349 N/A N/A d.110.4 SNARE-like
View Download 0.347 N/A N/A a.7.5 Tubulin chaperone cofactor A
View Download 0.203 N/A N/A c.55.4 Translational machinery components

Predicted Domain #4
Region A:
Residues: [506-647]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPAKKPATPA EDDEDDDIDL FGSDNEEEDK EAAQLREERL RQYAEKKAKK PALVAKSSIL  60
   61 LDVKPWDDET DMAQLEACVR SIQLDGLVWG ASKLVPVGYG IRKLQIQCVV EDDKVGTDLL 120
  121 EEEITKFEEH VQSVDIAAFN KI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.0
Match: 1b64A
Description: SOLUTION STRUCTURE OF THE GUANINE NUCLEOTIDE EXCHANGE FACTOR DOMAIN FROM HUMAN ELONGATION FACTOR-ONE BETA, NMR, 20 STRUCTURES
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle