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View Structure Prediction Details

Protein: RNF115
Organism: Homo sapiens
Length: 304 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RNF115.

Description E-value Query
Range
Subject
Range
gi|109015211 - gi|109015211|ref|XP_001089703.1| PREDICTED: similar to Rabring 7 [Macaca mulatta]
4.0E-54 [1..304] [1..304]
gi|114558417 - gi|114558417|ref|XP_514416.2| PREDICTED: similar to Zinc finger protein 364 isoform 2 [Pan troglodyt...
1.0E-53 [1..304] [1..304]
gi|12842450 - gi|12842450|dbj|BAB25607.1| unnamed protein product [Mus musculus]
4.0E-53 [18..304] [18..305]
gi|109467242, gi... - gi|34858089|ref|XP_342301.1| PREDICTED: similar to Zinc finger protein 364 (Rabring 7) [Rattus norve...
8.0E-53 [18..304] [18..305]
gi|73981400 - gi|73981400|ref|XP_850302.1| PREDICTED: similar to Zinc finger protein 364 (Rabring 7) [Canis famili...
3.0E-51 [18..304] [147..434]

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Predicted Domain #1
Region A:
Residues: [1-69]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEASAAGAD SGAAVAAHRF FCHFCKGEVS PKLPEYICPR CESGFIEEVT DDSSFLGGGG  60
   61 SRIDNTTTT

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.04
Match: 1y02A
Description: Crystal Structure of a FYVE-type domain from caspase regulator CARP2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.586512315637526 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [70-133]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HFAELWGHLD HTMFFQDFRP FLSSSPLDQD NRANERGHQT HTDFWGARPP RLPLGRRYRS  60
   61 RGSS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [134-304]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RPDRSPAIEG ILQHIFAGFF ANSAIPGSPH PFSWSGMLHS NPGDYAWGQT GLDAIVTQLL  60
   61 GQLENTGPPP ADKEKITSLP TVTVTQEQVD MGLECPVCKE DYTVEEEVRQ LPCNHFFHSS 120
  121 CIVPWLELHD TCPVCRKSLN GEDSTRQSQS TEASASNRFS NDSQLHDRWT F

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.522879
Match: 1z6uA
Description: Np95-like ring finger protein isoform b [Homo sapiens]
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle