YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|119608210, gi...
Organism:	Homo sapiens
Length:	659 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|119608210, gi....

Description	E-value	Query Range	Subject Range
gi\|109110122 - gi\|109110122\|ref\|XP_001110844.1\| PREDICTED: similar to GLE1-like, RNA export mediator isoform 1 isof...	0.0	[1..658]	[1..658]
GLE1_PONPY - Nucleoporin GLE1 - Pongo pygmaeus (Orangutan) GLE1_PONAB - Nucleoporin GLE1 OS=Pongo abelii GN=GLE1 PE=2 SV=1	0.0	[1..658]	[1..658]
gi\|62897267 - gi\|62897267\|dbj\|BAD96574.1\| GLE1-like, RNA export mediator isoform 1 variant [Homo sapiens]	0.0	[1..658]	[1..658]
GLE1_BOVIN - Nucleoporin GLE1 OS=Bos taurus GN=GLE1 PE=2 SV=1	0.0	[1..658]	[1..658]
gi\|20070897 - gi\|20070897\|gb\|AAH26797.1\| GLE1 RNA export mediator (yeast) [Mus musculus]	0.0	[1..658]	[1..658]
gi\|62651105, gi\|... - gi\|62651105\|ref\|XP_234442.3\| PREDICTED: similar to GLE1 RNA export mediator-like (yeast [Rattus norv...	0.0	[2..658]	[15..670]
gi\|114626990 - gi\|114626990\|ref\|XP_001159347.1\| PREDICTED: GLE1-like, RNA export mediator isoform 4 [Pan troglodyte...	0.0	[1..658]	[1..657]

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Predicted Domain #1

Region A:
Residues: [1-66]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSEGRCWET LKALRSSDKG RLCYYRDWLL RREDVLEECM SLPKLSSYSG WVVEHVLPHM  60
   61 QENQPL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [67-482]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SETSPSSTSA SALDQPSFVP KSPDASSAFS PASPATPNGT KGKDESQHTE SMVLQSSRGI  60
   61 KVEGCVRMYE LVHRMKGTEG LRLWQEEQER KVQALSEMAS EQLKRFDEWK ELKQHKEFQD 120
  121 LREVMEKSSR EALGHQEKLK AEHRHRAKIL NLKLREAEQQ RVKQAEQERL RKEEGQIRLR 180
  181 ALYALQEEML QLSQQLDASE QHKALLKVDL AAFQTRGNQL CSLISGIIRA SSESSYPTAE 240
  241 SQAEAERALR EMRDLLMNLG QEITRACEDK RRQDEEEAQV KLQEAQMQQG PEAHKEPPAP 300
  301 SQGPGGKQNE DLQVKVQDIT MQWYQQLQDA SMQCVLTFEG LTNSKDSQAK KIKMDLQKAA 360
  361 TIPVSQISTI AGSKLKEIFD KIHSLLSGKP VQSGGRSVSV TLNPQGLDFV QYKLAE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	24.0
Match:	1i84S
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [483-659]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KFVKQGEEEV ASHHEAAFPI AVVASGIWEL HPRVGDLILA HLHKKCPYSV PFYPTFKEGM  60
   61 ALEDYQRMLG YQVKDSKVEQ QDNFLKRMSG MIRLYAAIIQ LRWPYGNRQE IHPHGLNHGW 120
  121 RWLAQILNME PLSDVTATLL FDFLEVCGNA LMKQYQVQFW KMLILIKEDY FPRYQAC

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits