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View Structure Prediction Details

Protein: TCERG1
Organism: Homo sapiens
Length: 1098 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TCERG1.

Description E-value Query
Range
Subject
Range
gi|68388302 - gi|68388302|ref|XP_696268.1| PREDICTED: similar to slow myosin heavy chain 1 [Danio rerio]
0.0 [439..1098] [2246..2894]
TCERG1 - transcription elongation regulator 1
0.0 [1..1098] [1..1098]
gi|114602552 - gi|114602552|ref|XP_518017.2| PREDICTED: transcription elongation regulator 1 isoform 6 [Pan troglod...
0.0 [1..1098] [1..1104]
gi|50757613 - gi|50757613|ref|XP_415578.1| PREDICTED: similar to myosin heavy chain [Gallus gallus]
4.0E-99 [441..1098] [1202..1870]
gi|109079184 - gi|109079184|ref|XP_001101428.1| PREDICTED: similar to transcription elongation regulator 1 isoform ...
1.0E-98 [1..1098] [1..1096]
TCRG1_MOUSE - Transcription elongation regulator 1 OS=Mus musculus GN=Tcerg1 PE=1 SV=2
5.0E-97 [1..1098] [1..1100]
gi|109507254 - gi|109507254|ref|XP_001068365.1| PREDICTED: similar to Transcription elongation regulator 1 (TATA bo...
1.0E-96 [11..1098] [52..1129]

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Predicted Domain #1
Region A:
Residues: [1-415]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAERGGDGGE SERFNPGELR MAQQQALRFR GPAPPPNAVM RGPPPLMRPP PPFGMMRGPP  60
   61 PPPRPPFGRP PFDPNMPPMP PPGGIPPPMG PPHLQRPPFM PPPMSSMPPP PGMMFPPGMP 120
  121 PVTAPGTPAL PPTEEIWVEN KTPDGKVYYY NARTRESAWT KPDGVKVIQQ SELTPMLAAQ 180
  181 AQVQAQAQAQ AQAQAQAQAQ AQAQAQAQAQ AQAQAQAQAQ AQAQAQAQAQ AQAQAQAQAQ 240
  241 AQVQAQVQAQ VQAQAVGAST PTTSSPAPAV STSTSSSTPS STTSTTTTAT SVAQTVSTPT 300
  301 TQDQTPSSAV SVATPTVSVS TPAPTATPVQ TVPQPHPQTL PPAVPHSVPQ PTTAIPAFPP 360
  361 VMVPPFRVPL PGMPIPLPGV AMMQIVSCPY VKTVATTKTG VLPGMAPPIV PMIHP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.154902
Match: 1y0fB
Description: No description for 1y0fB was found.

Predicted Domain #2
Region A:
Residues: [416-580]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QVAIAASPAT LAGATAVSEW TEYKTADGKT YYYNNRTLES TWEKPQELKE KEKLEEKIKE  60
   61 PIKEPSEEPL PMETEEEDPK EEPIKEIKEE PKEEEMTEEE KAAQKAKPVA TAPIPGTPWC 120
  121 VVWTGDERVF FYNPTTRLSM WDRPDDLIGR ADVDKIIQEP PHKKG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.53
Match: 1o6wA
Description: Splicing factor prp40
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.526918523531992 bayes_pls_golite062009
protein binding 0.437950218081596 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [581-806]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEELKKLRHP TPTMLSIQKW QFSMSAIKEE QELMEEINED EPVKAKKRKR DDNKDIDSEK  60
   61 EAAMEAEIKA ARERAIVPLE ARMKQFKDML LERGVSAFST WEKELHKIVF DPRYLLLNPK 120
  121 ERKQVFDQYV KTRAEEERRE KKNKIMQAKE DFKKMMEEAK FNPRATFSEF AAKHAKDSRF 180
  181 KAIEKMKDRE ALFNEFVAAA RKKEKEDSKT RGEKIKSDFF ELLSNH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.0
Match: 1dg3A
Description: Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain; Interferon-induced guanylate-binding protein 1 (GBP1), N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [807-1098]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HLDSQSRWSK VKDKVESDPR YKAVDSSSMR EDLFKQYIEK IAKNLDSEKE KELERQARIE  60
   61 ASLREREREV QKARSEQTKE IDREREQHKR EEAIQNFKAL LSDMVRSSDV SWSDTRRTLR 120
  121 KDHRWESGSL LEREEKEKLF NEHIEALTKK KREHFRQLLD ETSAITLTST WKEVKKIIKE 180
  181 DPRCIKFSSS DRKKQREFEE YIRDKYITAK ADFRTLLKET KFITYRSKKL IQESDQHLKD 240
  241 VEKILQNDKR YLVLDCVPEE RRKLIVAYVD DLDRRGPPPP PTASEPTRRS TK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.69897
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle