YRC Public Data Repository - Protein Structure Prediction

Protein:	RPS12
Organism:	Homo sapiens
Length:	132 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RPS12.

Description	E-value	Query Range	Subject Range
gi\|114609445 - gi\|114609445\|ref\|XP_001155941.1\| PREDICTED: similar to 40S ribosomal protein S12 [Pan troglodytes]	4.0E-48	[6..132]	[228..354]
gi\|109088312, gi... - gi\|109088312\|ref\|XP_001090940.1\| PREDICTED: similar to ribosomal protein S12 isoform 3 [Macaca mulat...	1.0E-43	[1..132]	[1..132]
gi\|60654351 - gi\|60654351\|gb\|AAX29866.1\| ribosomal protein S12 [synthetic construct]	1.0E-43	[1..132]	[1..132]
RS12_CHICK - 40S ribosomal protein S12 OS=Gallus gallus GN=RPS12 PE=1 SV=2	2.0E-43	[1..132]	[1..132]
gi\|148231845, gi... - gi\|27881763\|gb\|AAH44028.1\| Rps12-prov protein [Xenopus laevis], gi\|148231845\|ref\|NP_001080594.1\| rib... gi\|51258906, gi\|... - gi\|89272933\|emb\|CAJ82890.1\| ribosomal protein S12 [Xenopus tropicalis], gi\|56605872\|ref\|NP_001008435...	3.0E-43	[1..132]	[1..132]
gi\|45504877, gi\|... - gi\|68402572\|ref\|XP_687451.1\| PREDICTED: similar to ribosomal protein S12 [Danio rerio], gi\|45504877\|... gi\|156914875, gi... - gi\|160420153\|ref\|NP_001104194.1\| hypothetical protein LOC100126614 [Xenopus laevis], gi\|156914875\|gb...	3.0E-43	[1..132]	[1..132]
gi\|147905512, gi... - gi\|34785258\|gb\|AAH56655.1\| MGC68529 protein [Xenopus laevis], gi\|147905512\|ref\|NP_001079902.1\| ribos...	1.0E-42	[1..132]	[1..132]
gi\|149250091, gi... - gi\|94368670\|ref\|XP_988610.1\| PREDICTED: similar to ribosomal protein S12 [Mus musculus], gi\|14925009...	1.0E-42	[1..132]	[1..132]
gi\|219500954, gi... - gi\|219500954\|ref\|XP_002246877.1\| hypothetical protein BRAFLDRAFT_109012 [Branchiostoma floridae], gi... gi\|18845074 - gi\|18845074\|gb\|AAL79538.1\|AF470687_1 40S ribosomal protein S12 [Branchiostoma belcheri]	1.0E-42	[1..131]	[1..131]
RS12_ORENI - 40S ribosomal protein S12 OS=Oreochromis niloticus GN=rps12 PE=2 SV=3	2.0E-42	[1..132]	[1..132]

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Predicted Domain #1

Region A:
Residues: [1-132]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEEGIAAGG VMDVNTALQE VLKTALIHDG LARGIREAAK ALDKRQAHLC VLASNCDEPM  60
   61 YVKLVEALCA EHQINLIKVD DNKKLGEWVG LCKIDREGKP RKVVGCSCVV VKDYGKESQA 120
  121 KDVIEEYFKC KK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	25.154902
Match:	2ozbA
Description:	No description for 2ozbA was found.

Predicted functions:

Term	Confidence	Notes
structural constituent of ribosome	7.52323416912124	bayes_pls_golite062009
structural molecule activity	6.97581143389173	bayes_pls_golite062009
RNA binding	3.17103797166833	bayes_pls_golite062009
nucleic acid binding	1.89156659324072	bayes_pls_golite062009
binding	1.71406048714822	bayes_pls_golite062009
	0.61812240381857	bayes_pls_golite062009
protein binding	0.281497939080747	bayes_pls_golite062009
catalytic activity	0.264002643439785	bayes_pls_golite062009
mRNA binding	0.259807967594031	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: