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View Structure Prediction Details

Protein: JUP
Organism: Homo sapiens
Length: 745 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for JUP.

Description E-value Query
Range
Subject
Range
gi|33875446 - gi|33875446|gb|AAH00441.2| JUP protein [Homo sapiens]
0.0 [1..745] [40..784]
PLAK_RAT - Junction plakoglobin OS=Rattus norvegicus GN=Jup PE=1 SV=1
0.0 [1..745] [1..745]
gi|109115422 - gi|109115422|ref|XP_001107394.1| PREDICTED: similar to junction plakoglobin [Macaca mulatta]
0.0 [1..745] [1..745]
PLAK_PIG - Junction plakoglobin OS=Sus scrofa GN=Jup PE=2 SV=1
0.0 [1..745] [1..745]
PLAK_MOUSE - Junction plakoglobin OS=Mus musculus GN=Jup PE=1 SV=3
0.0 [1..745] [1..745]
PLAK_BOVIN - Junction plakoglobin OS=Bos taurus GN=JUP PE=2 SV=1
0.0 [1..745] [1..745]

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Predicted Domain #1
Region A:
Residues: [1-141]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEVMNLMEQP IKVTEWQQTY TYDSGIHSGA NTCVPSVSSK GIMEEDEACG RQYTLKKTTT  60
   61 YTQGVPPSQG DLEYQMSTTA RAKRVREAMC PGVSGEDSSL LLATQVEGQA TNLQRLAEPS 120
  121 QLLKSAIVHL INYQDDAELA T

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 63.522879
Match: 1wa5B
Description: Crystal structure of the exportin Cse1p complexed with its cargo ( Kap60p) and RanGTP
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [142-322]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RALPELTKLL NDEDPVVVTK AAMIVNQLSK KEASRRALMG SPQLVAAVVR TMQNTSDLDT  60
   61 ARCTTSILHN LSHHREGLLA IFKSGGIPAL VRMLSSPVES VLFYAITTLH NLLLYQEGAK 120
  121 MAVRLADGLQ KMVPLLNKNN PKFLAITTDC LQLLAYGNQE SKLIILANGG PQALVQIMRN 180
  181 Y

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.154902
Match: 1oyzA
Description: X-RAY STRUCTURE OF YIBA_ECOLI NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ET31.
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [323-624]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SYEKLLWTTS RVLKVLSVCP SNKPAIVEAG GMQALGKHLT SNSPRLVQNC LWTLRNLSDV  60
   61 ATKQEGLESV LKILVNQLSV DDVNVLTCAT GTLSNLTCNN SKNKTLVTQN SGVEALIHAI 120
  121 LRAGDKDDIT EPAVCALRHL TSRHPEAEMA QNSVRLNYGI PAIVKLLNQP NQWPLVKATI 180
  181 GLIRNLALCP ANHAPLQEAA VIPRLVQLLV KAHQDAQRHV AAGTQQPYTD GVRMEEIVEG 240
  241 CTGALHILAR DPMNRMEIFR LNTIPLFVQL LYSSVENIQR VAAGVLCELA QDKEAADAID 300
  301 AE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.6
Match: 2gl7A
Description: No description for 2gl7A was found.

Predicted Domain #4
Region A:
Residues: [625-745]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GASAPLMELL HSRNEGTATY AAAVLFRISE DKNPDYRKRV SVELTNSLFK HDPAAWEAAQ  60
   61 SMIPINEPYG DDMDATYRPM YSSDVPLDPL EMHMDMDGDY PIDTYSDGLR PPYPTADHML 120
  121 A

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 86.0
Match: 2gl7A
Description: No description for 2gl7A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle