YRC Public Data Repository - Protein Structure Prediction

Protein:	ZDHHC14
Organism:	Homo sapiens
Length:	488 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ZDHHC14.

Description	E-value	Query Range	Subject Range
gi\|86129582, gi\|... - gi\|86129582\|ref\|NP_001034432.1\| zinc finger, DHHC-type containing 14 [Rattus norvegicus], gi\|6218416...	0.0	[1..488]	[1..489]
ZDH14_MOUSE - Probable palmitoyltransferase ZDHHC14 OS=Mus musculus GN=Zdhhc14 PE=1 SV=1	0.0	[1..488]	[1..489]
gi\|109072256 - gi\|109072256\|ref\|XP_001093039.1\| PREDICTED: similar to NEW1 domain containing protein isoform 1 isof...	0.0	[1..488]	[1..488]
gi\|24371272, gi\|... - gi\|24371272\|ref\|NP_714968.1\| zinc finger, DHHC-type containing 14 isoform 2 [Homo sapiens], gi\|24181...	0.0	[1..488]	[1..473]
gi\|114609928 - gi\|114609928\|ref\|XP_001143896.1\| PREDICTED: NEW1 domain containing protein isoform 1 [Pan troglodyte...	0.0	[25..488]	[1..464]
gi\|73946172 - gi\|73946172\|ref\|XP_854971.1\| PREDICTED: similar to NEW1 domain containing protein isoform 1 [Canis f...	0.0	[82..488]	[14..420]
gi\|50742608 - gi\|50742608\|ref\|XP_419692.1\| PREDICTED: similar to membrane-associated DHHC14 zinc finger protein is...	0.0	[1..488]	[1..476]

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Predicted Domain #1

Region A:
Residues: [1-136]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPGGGGPMK DCEYSQISTH SSSPMESPHK KKKIAARRKW EVFPGRNKFF CNGRIMMARQ  60
   61 TGVFYLTLVL ILVTSGLFFA FDCPYLAVKI TPAIPAVAGI LFFFVMGTLL RTSFSDPGVL 120
  121 PRATPDEAAD LERQID

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [137-211]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IANGTSSGGY RPPPRTKEVI INGQTVKLKY CFTCKIFRPP RASHCSLCDN CVERFDHHCP  60
   61 WVGNCVGKRN YRFFY

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.03
Match:	2cklB
Description:	No description for 2cklB was found.

Predicted Domain #3

Region A:
Residues: [212-334]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFILSLSFLT VFIFAFVITH VILRSQQTGF LNALKDSPAS VLEAVVCFFS VWSIVGLSGF  60
   61 HTYLISSNQT TNEDIKGSWS NKRGKENYNP YSYGNIFTNC CVALCGPISP SLIDRRGYIQ 120
  121 PDT

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [335-488]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQPAAPSNGI TMYGATQSQS DMCDQDQCIQ STKFVLQAAA TPLLQSEPSL TSDELHLPGK  60
   61 PGLGTPCASL TLGPPTPPAS MPNLAEATLA DVMPRKDEHM GHQFLTPDEA PSPPRLLAAG 120
  121 SPLAHSRTMH VLGLASQDSL HEDSVRGLVK LSSV

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.2
Match:	1h1kI
Description:	THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits