YRC Public Data Repository - Protein Structure Prediction

Protein:	Y3357_MYCTU, REL...
Organism:	Mycobacterium tuberculosis
Length:	91 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Y3357_MYCTU, REL....

Description	E-value	Query Range	Subject Range
YEFM_STRCO, Y223... - (Q9Z4V7) Hypothetical protein SCO2235 (ORFU1E), Antitoxin YefM OS=Streptomyces coelicolor GN=SCO2235... YEFM_STRCO - Antitoxin YefM OS=Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) GN=SCO2235 PE=3 SV=1	112.0	[0..1]	[87..1]
gi\|24113402, gi\|... - gi\|24113402\|ref\|NP_707912.1\| antitoxin YefM [Shigella flexneri 2a str. 301], gi\|24052422\|gb\|AAN43619... gi\|30063468, gi\|... - gi\|30063468\|ref\|NP_837639.1\| antitoxin YefM [Shigella flexneri 2a str. 2457T], gi\|30041721\|gb\|AAP174... YEFM_SHIFL - Antitoxin YefM OS=Shigella flexneri GN=yefM PE=3 SV=1 gi\|110805991, gi... - gi\|110805991\|ref\|YP_689511.1\| antitoxin YefM [Shigella flexneri 5 str. 8401], gi\|110615539\|gb\|ABF042...	106.0	[0..2]	[81..3]
gi\|77384858, gi\|... - gi\|77460855\|ref\|YP_350362.1\| prevent-host-death protein [Pseudomonas fluorescens Pf0-1], gi\|77384858...	106.0	[0..2]	[82..26]
gi\|75766065, gi\|... - gi\|75766067\|pdb\|2A6Q\|D Chain D, Crystal Structure Of Yefm-Yoeb Complex, gi\|75766066\|pdb\|2A6Q\|C Chain...	105.0	[0..2]	[81..6]
gi\|126097534, gi... - gi\|126208742\|ref\|YP_001053967.1\| antitoxin YefM [Actinobacillus pleuropneumoniae L20], gi\|126097534\|... gi\|46143500 - gi\|46143500\|ref\|ZP_00204491.1\| COG2161: Antitoxin of toxin-antitoxin stability system [Actinobacillu...	105.0	[0..2]	[81..3]
gi\|91778269, gi\|... - gi\|91778269\|ref\|YP_553477.1\| prevent-host-death protein [Burkholderia xenovorans LB400], gi\|91690929...	105.0	[0..3]	[84..4]
gi\|26248392, gi\|... - gi\|26248392\|ref\|NP_754432.1\| Hypothetical protein yefM [Escherichia coli CFT073], gi\|26108796\|gb\|AAN... gi\|227887067, gi... - gi\|227887067\|ref\|ZP_04004872.1\| prevent-host-death family protein [Escherichia coli 83972], gi\|22783... gi\|91072878, gi\|... - gi\|91211304\|ref\|YP_541290.1\| hypothetical protein YefM [Escherichia coli UTI89], gi\|91072878\|gb\|ABE0... gi\|75514059 - gi\|75514059\|ref\|ZP_00736389.1\| COG2161: Antitoxin of toxin-antitoxin stability system [Escherichia c...	103.0	[0..2]	[81..12]
YEFM_ECOLI - Antitoxin yefM - Escherichia coli EG12844 - antitoxin of the YoeB-YefM toxin-antitoxin system / Antitoxin for YoeB toxin; binds YoeB RNase-like ... gi\|89108838, gi\|... - gi\|89108838\|ref\|AP_002618.1\| antitoxin of the YoeB-YefM toxin-antitoxin system [Escherichia coli str... gi\|209919482, gi... - gi\|209919482\|ref\|YP_002293566.1\| antitoxin YefM [Escherichia coli SE11], gi\|209912741\|dbj\|BAG77815.1... gi\|238901208, gi... - gi\|238901208\|ref\|YP_002927004.1\| antitoxin of the YoeB-YefM toxin-antitoxin system [Escherichia coli... gi\|194428783, gi... - gi\|194428783\|ref\|ZP_03061319.1\| addiction module antitoxin component YefM [Escherichia coli B171], g... gi\|226237425 - gi\|226237425\|dbj\|BAH46947.1\| antitoxin of the YoeB-YefM toxin-antitoxin system [Escherichia coli O55... gi\|218549431, gi... - gi\|218549431\|ref\|YP_002383222.1\| antitoxin YefM [Escherichia fergusonii ATCC 35469], gi\|218356972\|em... gi\|215265311, gi... - gi\|215487239\|ref\|YP_002329670.1\| antitoxin YefM [Escherichia coli O127:H6 str. E2348/69], gi\|2152653... gi\|191170193, gi... - gi\|75242851\|ref\|ZP_00726557.1\| COG2161: Antitoxin of toxin-antitoxin stability system [Escherichia c... gi\|218365668, gi... - gi\|218558899\|ref\|YP_002391812.1\| antitoxin YefM [Escherichia coli S88], gi\|218365668\|emb\|CAR03405.1\|... gi\|73856037, gi\|... - gi\|74312560\|ref\|YP_310979.1\| antitoxin YefM [Shigella sonnei Ss046], gi\|73856037\|gb\|AAZ88744.1\| cons... gi\|218554580, gi... - gi\|218554580\|ref\|YP_002387493.1\| antitoxin YefM [Escherichia coli IAI1], gi\|218361348\|emb\|CAQ98936.1... gi\|83588019, gi\|... - gi\|83588019\|ref\|ZP_00926644.1\| COG2161: Antitoxin of toxin-antitoxin stability system [Escherichia c... gi\|193071575, gi... - gi\|75214864\|ref\|ZP_00713345.1\| COG2161: Antitoxin of toxin-antitoxin stability system [Escherichia c... gi\|218352375, gi... - gi\|218695643\|ref\|YP_002403310.1\| antitoxin YefM [Escherichia coli 55989], gi\|218352375\|emb\|CAU98149.... gi\|161984963 - gi\|161984963\|ref\|YP_407341.2\| antitoxin YefM [Shigella boydii Sb227] YEFM_ECOL6 - Antitoxin YefM OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=yefM PE=3 SV=1 gi\|170081648, gi... - gi\|170081648\|ref\|YP_001730968.1\| antitoxin of the YoeB-YefM toxin-antitoxin system [Escherichia coli... gi\|162138416 - gi\|162138416\|ref\|YP_541290.2\| antitoxin YefM [Escherichia coli UTI89] EG12844 - antitoxin of the YoeB-YefM toxin-antitoxin system / Antitoxin for YoeB toxin; binds YoeB RNase-like ... gi\|188492661, gi... - gi\|188492661\|ref\|ZP_02999931.1\| antitoxin YefM [Escherichia coli 53638], gi\|188487860\|gb\|EDU62963.1\|... gi\|187428195, gi... - gi\|187731203\|ref\|YP_001879859.1\| antitoxin YefM [Shigella boydii CDC 3083-94], gi\|187428195\|gb\|ACD07... gi\|192931567, gi... - gi\|193062924\|ref\|ZP_03044017.1\| addiction module antitoxin component YefM [Escherichia coli E22], gi... gi\|190902252, gi... - gi\|191167739\|ref\|ZP_03029547.1\| addiction module antitoxin component YefM [Escherichia coli B7A], gi... gi\|110642231, gi... - gi\|110642231\|ref\|YP_669961.1\| antitoxin YefM [Escherichia coli 536], gi\|110343823\|gb\|ABG70060.1\| hyp... YEFM_ECOL6 - Antitoxin YefM OS=Escherichia coli O6 GN=yefM PE=3 SV=1 gi\|157067190, gi... - gi\|157161510\|ref\|YP_001458828.1\| antitoxin YefM [Escherichia coli HS], gi\|157067190\|gb\|ABV06445.1\| a... gi\|157081490, gi... - gi\|157159460\|ref\|YP_001463369.1\| antitoxin YefM [Escherichia coli E24377A], gi\|157081490\|gb\|ABV21198...	103.0	[0..2]	[81..3]
gi\|75196085 - gi\|75196085\|ref\|ZP_00706155.1\| COG2161: Antitoxin of toxin-antitoxin stability system [Escherichia c... gi\|75210038 - gi\|75210038\|ref\|ZP_00710221.1\| COG2161: Antitoxin of toxin-antitoxin stability system [Escherichia c... gi\|7467161 - gi\|7467161\|pir\|\|H64966 yefM protein - Escherichia coli (strain K-12) gi\|75229121 - gi\|75229121\|ref\|ZP_00715696.1\| COG2161: Antitoxin of toxin-antitoxin stability system [Escherichia c... gi\|1788328, gi\|1... - gb\|AAC75078.1\| orf, hypothetical protein; conserved hypothetical protein [Escherichia coli K12], gi... gi\|75259167 - gi\|75259167\|ref\|ZP_00730515.1\| COG2161: Antitoxin of toxin-antitoxin stability system [Escherichia c... gi\|117624221, gi... - gi\|117624221\|ref\|YP_853134.1\| antitoxin YefM [Escherichia coli APEC O1], gi\|115513345\|gb\|ABJ01420.1\|... gi\|82543394, gi\|... - gi\|82543394\|ref\|YP_407341.1\| hypothetical protein SBO_0843 [Shigella boydii Sb227], gi\|81244805\|gb\|A... gi\|237704475, gi... - gi\|237704475\|ref\|ZP_04534956.1\| antitoxin YefM [Escherichia sp. 3_2_53FAA], gi\|226900841\|gb\|EEH87100... gi\|75177145 - gi\|75177145\|ref\|ZP_00697243.1\| COG2161: Antitoxin of toxin-antitoxin stability system [Shigella boyd... gi\|75186825 - gi\|75186825\|ref\|ZP_00700092.1\| COG2161: Antitoxin of toxin-antitoxin stability system [Escherichia c...	102.0	[0..2]	[81..12]
gi\|87120886, gi\|... - gi\|87120886\|ref\|ZP_01076778.1\| hypothetical protein MED121_09765 [Marinomonas sp. MED121], gi\|861637...	101.0	[0..2]	[81..3]

Back

Predicted Domain #1

Region A:
Residues: [1-91]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSISASEARQ RLFPLIEQVN TDHQPVRITS RAGDAVLMSA DDYDAWQETV YLLRSPENAR  60
   61 RLMEAVARDK AGHSAFTKSV DELREMAGGE E

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	23.69897
Match:	2a6qA
Description:	Crystal structure of YefM-YoeB complex
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits