YRC Public Data Repository - Protein Structure Prediction

Protein:	YTFG_ECOLI
Organism:	Escherichia coli
Length:	286 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YTFG_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|41205692 - gi\|41205692\|gb\|AAR99612.1\| dTDP-glucose 4,6-dehydratase [Geobacillus stearothermophilus]	221.0	[0..2]	[284..5]
gi\|33413324, gi\|... - gi\|33413324\|emb\|CAD67949.1\| putative dTDP-glucose 4,6-dehydratase [Thermotoga sp. RQ2], gi\|170288108...	211.0	[0..2]	[284..3]
gi\|7437238 - pir\|\|H69105 dTDP-glucose 4,6-dehydratase - Methanobacterium thermoautotrophicum (strain Delta H) gi\|15679777, gi\|... - gi\|2622920\|gb\|AAB86255.1\| dTDP-glucose 4,6-dehydratase [Methanothermobacter thermautotrophicus str. ...	211.0	[0..2]	[284..4]
gi\|160876126, gi... - gi\|160876126\|ref\|YP_001555442.1\| dTDP-glucose 4,6-dehydratase [Shewanella baltica OS195], gi\|1608616...	207.0	[0..2]	[284..3]
SO3167 - dTDP-glucose 46-dehydratase gi\|24374680, gi\|... - gi\|24374680\|ref\|NP_718723.1\| dTDP-glucose 4,6-dehydratase [Shewanella oneidensis MR-1], gi\|24349325\|...	206.0	[0..2]	[284..3]
gi\|86144027, gi\|... - gi\|86144027\|ref\|ZP_01062365.1\| dTDP-D-glucose 4,6-dehydratase [Flavobacterium sp. MED217], gi\|858294... gi\|86144027, gi\|... - gi\|86144027\|ref\|ZP_01062365.1\| dTDP-D-glucose 4,6-dehydratase [Flavobacterium sp. MED217], gi\|858294...	206.0	[0..2]	[284..3]
gi\|68551274, gi\|... - gi\|68551274\|ref\|ZP_00590692.1\| dTDP-glucose 4,6-dehydratase [Pelodictyon phaeoclathratiforme BU-1], ...	206.0	[0..2]	[284..44]
gi\|110833771, gi... - gi\|110833771\|ref\|YP_692630.1\| dTDP-glucose 4,6-dehydratase [Alcanivorax borkumensis SK2], gi\|1106468...	205.0	[0..2]	[284..3]
gi\|98663078 - gi\|98663078\|dbj\|GAA00145.1\| unnamed protein product [Pelotomaculum thermopropionicum SI]	204.0	[0..3]	[284..15]

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Predicted Domain #1

Region A:
Residues: [1-286]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIAITGATGQ LGHYVIESLM KTVPASQIVA IVRNPAKAQA LAAQGITVRQ ADYGDEAALT  60
   61 SALQGVEKLL LISSSEVGQR APQHRNVINA AKAAGVKFIA YTSLLHADTS PLGLADEHIE 120
  121 TEKMLADSGI VYTLLRNGWY SENYLASAPA ALEHGVFIGA AGDGKIASAT RADYAAAAAR 180
  181 VISEAGHEGK VYELAGDSAW TLTQLAAELT KQSGKQVTYQ NLSEADFAAA LKSVGLPDGL 240
  241 ADMLADSDVG ASKGGLFDDS KTLSKLIGHP TTTLAESVSH LFNVNN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	51.30103
Match:	1bxkA
Description:	dTDP-glucose 4,6-dehydratase (RmlB)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.03099072397093	bayes_pls_golite062009
oxidoreductase activity	0.442294542097958	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: