YRC Public Data Repository - Protein Structure Prediction

Protein:	YRAL_ECOLI
Organism:	Escherichia coli
Length:	286 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YRAL_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|187429789, gi... - gi\|75176252\|ref\|ZP_00696404.1\| COG0313: Predicted methyltransferases [Shigella boydii BS512], gi\|187... gi\|81247025, gi\|... - gi\|82545614\|ref\|YP_409561.1\| hypothetical protein SBO_3236 [Shigella boydii Sb227], gi\|81247025\|gb\|A...	280.0	[0..1]	[286..1]
gi\|84374943, gi\|... - gi\|84394444\|ref\|ZP_00993160.1\| hypothetical protein V12B01_10023 [Vibrio splendidus 12B01], gi\|84374...	277.0	[0..1]	[283..1]
gi\|89074180, gi\|... - gi\|89074180\|ref\|ZP_01160679.1\| putative methyltransferase [Photobacterium sp. SKA34], gi\|89050116\|gb...	276.0	[0..1]	[283..1]
gi\|86148531, gi\|... - gi\|86148531\|ref\|ZP_01066818.1\| hypothetical protein MED222_16878 [Vibrio sp. MED222], gi\|85833677\|gb... gi\|218321496, gi... - gi\|218708477\|ref\|YP_002416098.1\| hypothetical protein VS_0440 [Vibrio splendidus LGP32], gi\|21832149...	276.0	[0..1]	[283..1]
gi\|91228504, gi\|... - gi\|91228504\|ref\|ZP_01262426.1\| hypothetical protein V12G01_00255 [Vibrio alginolyticus 12G01], gi\|91...	276.0	[0..1]	[283..1]
gi\|254230426, gi... - gi\|75854414\|ref\|ZP_00762109.1\| COG0313: Predicted methyltransferases [Vibrio sp. Ex25], gi\|254230426...	276.0	[0..1]	[283..1]
gi\|153830238, gi... - gi\|153830238\|ref\|ZP_01982905.1\| conserved hypothetical protein [Vibrio cholerae 623-39], gi\|14887429... gi\|125620619, gi... - gi\|75818067\|ref\|ZP_00748291.1\| COG0313: Predicted methyltransferases [Vibrio cholerae V51], gi\|25422...	275.0	[0..1]	[283..1]
gi\|90438520, gi\|... - gi\|90580218\|ref\|ZP_01236025.1\| putative methyltransferase [Vibrio angustum S14], gi\|90438520\|gb\|EAS6...	275.0	[0..1]	[283..1]
gi\|149747465, gi... - gi\|153839037\|ref\|ZP_01991704.1\| conserved hypothetical protein [Vibrio parahaemolyticus AQ3810], gi\|... gi\|28897224, gi\|... - gi\|28897224\|ref\|NP_796829.1\| hypothetical protein VP0450 [Vibrio parahaemolyticus RIMD 2210633], gi\|... gi\|28805433 - gi\|28805433\|dbj\|BAC58713.1\| conserved hypothetical protein [Vibrio parahaemolyticus RIMD 2210633]	274.0	[0..1]	[283..1]
gi\|59480918, gi\|... - gi\|59712817\|ref\|YP_205593.1\| methyltransferase [Vibrio fischeri ES114], gi\|59480918\|gb\|AAW86705.1\| p...	273.0	[0..1]	[283..23]

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Predicted Domain #1

Region A:
Residues: [1-286]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKQHQSADNS QGQLYIVPTP IGNLADITQR ALEVLQAVDL IAAEDTRHTG LLLQHFGINA  60
   61 RLFALHDHNE QQKAETLLAK LQEGQNIALV SDAGTPLIND PGYHLVRTCR EAGIRVVPLP 120
  121 GPCAAITALS AAGLPSDRFC YEGFLPAKSK GRRDALKAIE AEPRTLIFYE STHRLLDSLE 180
  181 DIVAVLGESR YVVLARELTK TWETIHGAPV GELLAWVKED ENRRKGEMVL IVEGHKAQEE 240
  241 DLPADALRTL ALLQAELPLK KAAALAAEIH GVKKNALYKY ALEQQG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	55.30103
Match:	1pjqA
Description:	Structure and function of CysG, the multifunctional methyltransferase/dehydrogenase/ferrochelatase for siroheme synthesis
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.717067613271007	bayes_pls_golite062009
transferase activity	0.408379218701484	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: