YRC Public Data Repository - Protein Structure Prediction

Protein:	YIEM_ECOLI, VIAA...
Organism:	Escherichia coli
Length:	483 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YIEM_ECOLI, VIAA....

Description	E-value	Query Range	Subject Range
gi\|24115048, gi\|... - gi\|24115048\|ref\|NP_709558.1\| hypothetical protein SF3825 [Shigella flexneri 2a str. 301], gi\|2405430... VIAA_SHIFL - Protein ViaA OS=Shigella flexneri GN=viaA PE=3 SV=1	361.0	[0..1]	[473..1]
VIAA_SHIF8 - Protein ViaA OS=Shigella flexneri serotype 5b (strain 8401) GN=viaA PE=3 SV=1	360.0	[0..1]	[473..1]
VIAA_ECO45 - Protein ViaA OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=viaA PE=3 SV=1 gi\|237703546, gi... - gi\|237703546\|ref\|ZP_04534027.1\| viaA [Escherichia sp. 3_2_53FAA], gi\|226902810\|gb\|EEH89069.1\| viaA [... VIAA_ECOUT - Protein ViaA OS=Escherichia coli (strain UTI89 / UPEC) GN=viaA PE=3 SV=1 VIAA_ECOL6 - Protein ViaA OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=viaA PE=3 SV=1 VIAA_ECOL6 - Protein viaA OS=Escherichia coli O6 GN=viaA PE=3 SV=1 VIAA_ECOK1 - Protein ViaA OS=Escherichia coli O1:K1 / APEC GN=viaA PE=3 SV=1	358.0	[0..1]	[473..1]
gi\|75242467, gi\|... - gi\|75242467\|ref\|ZP_00726211.1\| COG2425: Uncharacterized protein containing a von Willebrand factor t... VIAA_ECOL5 - Protein ViaA OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=viaA PE=3 SV=1	358.0	[0..1]	[473..1]
VIAA_SHIB3 - Protein ViaA OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=viaA PE=3 SV=1	358.0	[0..1]	[473..1]
gi\|191169199, gi... - gi\|75227514\|ref\|ZP_00714275.1\| COG2425: Uncharacterized protein containing a von Willebrand factor t... VIAA_ECO24 - Protein ViaA OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=viaA PE=3 SV=1 VIAA_ECOSE - Protein ViaA OS=Escherichia coli (strain SE11) GN=viaA PE=3 SV=1	357.0	[0..1]	[473..1]
gi\|188487291, gi... - gi\|75514189\|ref\|ZP_00736497.1\| COG2425: Uncharacterized protein containing a von Willebrand factor t...	357.0	[0..1]	[473..1]
gi\|124499446, gi... - gi\|124530041\|ref\|ZP_01700824.1\| von Willebrand factor, type A [Escherichia coli B], gi\|124499446\|gb\|... VIAA_ECOHS - Protein ViaA OS=Escherichia coli O9:H4 (strain HS) GN=viaA PE=3 SV=1 gi\|242379283, gi... - gi\|251787010\|ref\|YP_003001314.1\| hypothetical protein B21_03573 [Escherichia coli BL21], gi\|24237928... gi\|83588390, gi\|... - gi\|83588390\|ref\|ZP_00927014.1\| COG2425: Uncharacterized protein containing a von Willebrand factor t... gi\|254163696, gi... - gi\|254163696\|ref\|YP_003046804.1\| predicted von Willibrand factor containing protein [Escherichia col... VIAA_ECOLC - Protein ViaA OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=viaA PE=3 SV=1 gi\|254290447, gi... - gi\|254290447\|ref\|YP_003056195.1\| predicted von Willibrand factor containing protein [Escherichia col...	357.0	[0..1]	[473..1]
VIAA_SHIDS - Protein ViaA OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=viaA PE=3 SV=1	355.0	[0..1]	[473..1]
gi\|214001337 - gi\|214001337\|ref\|ZP_03412072.1\| hypothetical protein Salmonellentericaenterica_12915 [Salmonella ent... gi\|213418541 - gi\|213418541\|ref\|ZP_03351607.1\| hypothetical protein Salmonentericaenterica_11917 [Salmonella enteri... gi\|213427457 - gi\|213427457\|ref\|ZP_03360207.1\| hypothetical protein SentesTyphi_18791 [Salmonella enterica subsp. e... VIAA_SALTI - Protein viaA OS=Salmonella typhi GN=viaA PE=3 SV=1 gi\|213649871 - gi\|213649871\|ref\|ZP_03379924.1\| hypothetical protein SentesTy_22876 [Salmonella enterica subsp. ente... gi\|16762448 - gi\|16762448\|ref\|NP_458065.1\| hypothetical protein STY3900 [Salmonella enterica subsp. enterica serov... VIAA_SALTI - Protein ViaA OS=Salmonella typhi GN=viaA PE=3 SV=1 gi\|29143936, gi\|... - gi\|29143936\|ref\|NP_807278.1\| hypothetical protein t3641 [Salmonella enterica subsp. enterica serovar...	353.0	[0..1]	[473..1]

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Predicted Domain #1

Region A:
Residues: [1-119]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLTLDTLNVM LAVSEEGLIE EMIIALLASP QLAVFFEKFP RLKAAITDDV PRWREALRSR  60
   61 LKDARVPPEL TEEVMCYQQS QLLSTPQFIV QLPQILDLLH RLNSPWAEQA RQLVDANST

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [120-483]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ITSALHTLFL QRWRLSLIVQ ATTLNQQLLE EEREQLLSEV QERMTLSGQL EPILADNNTA  60
   61 AGRLWDMSAG QLKRGDYQLI VKYGEFLNEQ PELKRLAEQL GRSREAKSIP RNDAQMETFR 120
  121 TMVREPATVP EQVDGLQQSD DILRLLPPEL ATLGITELEY EFYRRLVEKQ LLTYRLHGES 180
  181 WREKVIERPV VHKDYDEQPR GPFIVCVDTS GSMGGFNEQC AKAFCLALMR IALAENRRCY 240
  241 IMLFSTEIVR YELSGPQGIE QAIRFLSQQF RGGTDLASCF RAIMERLQSR EWFDADAVVI 300
  301 SDFIAQRLPD DVTSKVKELQ RVHQHRFHAV AMSAHGKPGI MRIFDHIWRF DTGMRSRLLR 360
  361 RWRR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	10.0
Match:	1yvpA
Description:	Ro autoantigen complexed with RNAs
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.478378407636654	bayes_pls_golite062009
protein binding	0.0696520417739894	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: