YRC Public Data Repository - Protein Structure Prediction

Protein:	YHAO_ECOLI
Organism:	Escherichia coli
Length:	443 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YHAO_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|68373624 - gi\|68373624\|ref\|XP_692242.1\| PREDICTED: similar to Cationic amino acid transporter 3 (CAT-3) (Solute...	274.0	[0..23]	[416..965]
gi\|91084137 - gi\|91084137\|ref\|XP_969912.1\| PREDICTED: similar to CG8475-PA, isoform A [Tribolium castaneum]	259.0	[0..16]	[415..2462]
gi\|47221082 - gi\|47221082\|emb\|CAG12776.1\| unnamed protein product [Tetraodon nigroviridis]	239.0	[0..22]	[415..12]
gi\|46115126, gi\|... - gi\|46115126\|ref\|XP_383581.1\| hypothetical protein FG03405.1 [Gibberella zeae PH-1], gi\|42548380\|gb\|E...	232.0	[0..12]	[423..15]
gi\|238482071, gi... - gi\|238482071\|ref\|XP_002372274.1\| amino acid permease (Gap1), putative [Aspergillus flavus NRRL3357],... gi\|169765514 - gi\|169765514\|ref\|XP_001817228.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83765083 - gi\|83765083\|dbj\|BAE55226.1\| unnamed protein product [Aspergillus oryzae]	226.0	[0..20]	[421..67]
gi\|50746939 - gi\|50746939\|ref\|XP_420685.1\| PREDICTED: similar to cationic amino acid transporter-2 [Gallus gallus]	226.0	[0..21]	[416..19]
gi\|116181860, gi... - gi\|88185855\|gb\|EAQ93323.1\| hypothetical protein CHGG_01558 [Chaetomium globosum CBS 148.51], gi\|1161...	224.0	[0..21]	[441..99]
gi\|85095443 - gi\|85095443\|ref\|XP_960090.1\| general amino-acid permease GAP1 [Neurospora crassa OR74A] gi\|32410409, gi\|... - gi\|32410409\|ref\|XP_325685.1\| hypothetical protein [Neurospora crassa], gi\|28921549\|gb\|EAA30854.1\| ge...	222.0	[0..25]	[419..139]

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Predicted Domain #1

Region A:
Residues: [1-443]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEIASNKGVI ADASTPAGRA GMSESEWREA IKFDSTDTGW VIMSIGMAIG AGIVFLPVQV  60
   61 GLMGLWVFLL SSVIGYPAMY LFQRLFINTL AESPECKDYP SVISGYLGKN WGILLGALYF 120
  121 VMLVIWMFVY STAITNDSAS YLHTFGVTEG LLSDSPFYGL VLICILVAIS SRGEKLLFKI 180
  181 STGMVLTKLL VVAALGVSMV GMWHLYNVGS LPPLGLLVKN AIITLPFTLT SILFIQTLSP 240
  241 MVISYRSREK SIEVARHKAL RAMNIAFGIL FVTVFFYAVS FTLAMGHDEA VKAYEQNISA 300
  301 LAIAAQFISG DGAAWVKVVS VILNIFAVMT AFFGVYLGFR EATQGIVMNI LRRKMPAEKI 360
  361 NENLVQRGIM IFAILLAWSA IVLNAPVLSF TSICSPIFGM VGCLIPAWLV YKVPALHKYK 420
  421 GMSLYLIIVT GLLLCVSPFL AFS

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.36
Match:	2a65A
Description:	Crystal structure of LEUTAA, a bacterial homolog of Na+/Cl--dependent neurotransmitter transporters
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits