YRC Public Data Repository - Protein Structure Prediction

Protein:	YGCE_ECOLI
Organism:	Escherichia coli
Length:	492 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YGCE_ECOLI.

Description	E-value	Query Range	Subject Range
GLPK_CARHZ - Glycerol kinase OS=Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901) GN=gl...	500.0	[0..1]	[467..1]
GLPK2_THEMA, GLK... - Glycerol kinase 2 OS=Thermotoga maritima GN=glpK2 PE=3 SV=2, (Q9X1E4) Glycerol kinase 2 (EC 2.7.1.30... GLPK2_THEMA - Glycerol kinase 2 OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) GN=glpK2 ...	499.0	[0..4]	[463..2]
gi\|254479176, gi... - gi\|254479176\|ref\|ZP_05092524.1\| glycerol kinase [Carboxydibrachium pacificum DSM 12653], gi\|22348899... GLPK_CALS4 - Glycerol kinase OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 ... GLPK_THETN - Glycerol kinase OS=Thermoanaerobacter tengcongensis GN=glpK PE=3 SV=1	497.0	[0..1]	[464..1]
GLPK_PYRAB - Glycerol kinase OS=Pyrococcus abyssi GN=glpK PE=3 SV=1 GLPK_PYRAB - Glycerol kinase OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=glpK PE=3 SV=1	489.0	[0..1]	[464..1]
gi\|242257967, gi... - gi\|242257967\|ref\|ZP_04802809.1\| glycerol kinase [Thermoanaerobacter sp. X513], gi\|242230500\|gb\|EES32... GLPK_THEPX - Glycerol kinase OS=Thermoanaerobacter sp. (strain X514) GN=glpK PE=3 SV=1	487.0	[0..1]	[464..1]
GLPK_PYRKO - Glycerol kinase OS=Pyrococcus kodakaraensis GN=glpK PE=1 SV=2 GLPK_THEKO - Glycerol kinase OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) GN=glpK PE=1 S...	484.0	[0..3]	[464..2]
GLPK_THEP3 - Glycerol kinase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) GN=glpK PE=3 SV=1 gi\|241903306, gi... - gi\|241903306\|ref\|ZP_04788032.1\| glycerol kinase [Thermoanaerobacter brockii subsp. finnii Ako-1], gi...	483.0	[0..1]	[464..1]
gi\|7434247 - gi\|7434247\|pir\|\|C72254 glycerol kinase - Thermotoga maritima (strain MSB8) gi\|15644181, gi\|... - gi\|4981995\|gb\|AAD36500.1\|AE001795_3 glycerol kinase [Thermotoga maritima MSB8], gi\|15644181\|ref\|NP_2...	483.0	[0..4]	[449..2]
GLPK_BACHK - Glycerol kinase OS=Bacillus thuringiensis subsp. konkukian GN=glpK PE=3 SV=1 gi\|228814930, gi... - gi\|228944758\|ref\|ZP_04107122.1\| Glycerol kinase [Bacillus thuringiensis serovar monterrey BGSC 4AJ1]... gi\|228913716, gi... - gi\|228913716\|ref\|ZP_04077342.1\| Glycerol kinase [Bacillus thuringiensis serovar pulsiensis BGSC 4CC1... GLPK_BACC0 - Glycerol kinase OS=Bacillus cereus (strain AH820) GN=glpK PE=3 SV=1 GLPK_BACAC - Glycerol kinase OS=Bacillus anthracis (strain CDC 684 / NRRL 3495) GN=glpK PE=3 SV=1 GLPK_BACC7 - Glycerol kinase OS=Bacillus cereus (strain AH187) GN=glpK PE=3 SV=1 gi\|190566637, gi... - gi\|190566637\|ref\|ZP_03019554.1\| glycerol kinase [Bacillus anthracis Tsiankovskii-I], gi\|190562189\|gb... gi\|254682792 - gi\|254682792\|ref\|ZP_05146653.1\| glycerol kinase [Bacillus anthracis str. CNEVA-9066] gi\|228645684, gi... - gi\|229137827\|ref\|ZP_04266429.1\| Glycerol kinase [Bacillus cereus BDRD-ST26], gi\|228645684\|gb\|EEL0191... gi\|229120647, gi... - gi\|229120647\|ref\|ZP_04249891.1\| Glycerol kinase [Bacillus cereus 95/8201], gi\|228662820\|gb\|EEL18416.... gi\|228693308, gi... - gi\|229090078\|ref\|ZP_04221329.1\| Glycerol kinase [Bacillus cereus Rock3-42], gi\|228693308\|gb\|EEL47018... gi\|254758584 - gi\|254758584\|ref\|ZP_05210611.1\| glycerol kinase [Bacillus anthracis str. Australia 94] gi\|254753487 - gi\|254753487\|ref\|ZP_05205523.1\| glycerol kinase [Bacillus anthracis str. Vollum] GLPK_BACHK - Glycerol kinase OS=Bacillus thuringiensis subsp. konkukian (strain 97-27) GN=glpK PE=3 SV=1 gi\|254740147 - gi\|254740147\|ref\|ZP_05197839.1\| glycerol kinase [Bacillus anthracis str. Kruger B] gi\|254725580 - gi\|254725580\|ref\|ZP_05187362.1\| glycerol kinase [Bacillus anthracis str. A1055]	482.0	[0..3]	[460..2]

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Predicted Domain #1

Region A:
Residues: [1-492]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKKYIIGID GGSQSTKVVM YDLEGNVVCE GKGLLQPMHT PDADTAEHPD DDLWASLCFA  60
   61 GHDLMSQFAG NKEDIVGIGL GSIRCCRALL KADGTPAAPL ISWQDARVTR PYEHTNPDVA 120
  121 YVTSFSGYLT HRLTGEFKDN IANYFGQWPV DYKSWAWSED AAVMDKFNIP RHMLFDVQMP 180
  181 GTVLGHITPQ AALATHFPAG LPVVCTTSDK PVEALGAGLL DDETAVISLG TYIALMMNGK 240
  241 ALPKDPVAYW PIMSSIPQTL LYEGYGIRKG MWTVSWLRDM LGESLIQDAR AQDLSPEDLL 300
  301 NKKASCVPPG CNGLMTVLDW LTNPWEPYKR GIMIGFDSSM DYAWIYRSIL ESVALTLKNN 360
  361 YDNMCNEMNH FAKHVIITGG GSNSDLFMQI FADVFNLPAR RNAINGCASL GAAINTAVGL 420
  421 GLYPDYATAV DNMVRVKDIF IPIESNAKRY DAMNKGIFKD LTKHTDVILK KSYEVMHGEL 480
  481 GNVDSIQSWS NA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	135.0
Match:	2p3rA
Description:	No description for 2p3rA was found.

Predicted functions:

Term	Confidence	Notes
glycerol kinase activity	2.81995993272027	bayes_pls_golite062009
carbohydrate kinase activity	2.33338276303563	bayes_pls_golite062009
hexokinase activity	1.70516840340504	bayes_pls_golite062009
binding	1.28018709416814	bayes_pls_golite062009
protein binding	0.856838411407636	bayes_pls_golite062009
glucokinase activity	0.47468456642723	bayes_pls_golite062009
kinase activity	0.460541310603011	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.381597272143844	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.324655711623803	bayes_pls_golite062009
glucose binding	0.31060748948812	bayes_pls_golite062009
catalytic activity	0.296484721581333	bayes_pls_golite062009
transferase activity	0.105619024604158	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: