YRC Public Data Repository - Protein Structure Prediction

Protein:	YGBT_ECOLI
Organism:	Escherichia coli
Length:	305 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YGBT_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|106880978, gi... - gi\|119945309\|ref\|YP_942989.1\| CRISPR-associated Cas1 family protein [Psychromonas ingrahamii 37], gi...	332.0	[0..1]	[305..1]
gi\|47104059, gi\|... - gi\|47104059\|ref\|YP_015488.1\| hypothetical protein PBPRC0034 [Photobacterium profundum SS9], gi\|46911...	329.0	[0..1]	[304..1]
gi\|188494089, gi... - gi\|75512335\|ref\|ZP_00734887.1\| COG1518: Uncharacterized protein predicted to be involved in DNA repa...	328.0	[0..1]	[305..1]
gi\|75196729, gi\|... - gi\|75196729\|ref\|ZP_00706799.1\| COG1518: Uncharacterized protein predicted to be involved in DNA repa...	326.0	[0..1]	[305..1]
gi\|71543720, gi\|... - gi\|71543720\|ref\|ZP_00664797.1\| Protein of unknown function DUF48 [Syntrophobacter fumaroxidans MPOB]...	324.0	[0..5]	[303..7]
gi\|62129073, gi\|... - gi\|62181440\|ref\|YP_217857.1\| putative cytoplasmic protein [Salmonella enterica subsp. enterica serov... gi\|224469244, gi... - gi\|224584717\|ref\|YP_002638515.1\| putative cytoplasmic protein [Salmonella enterica subsp. enterica s... gi\|198243044, gi... - gi\|198243044\|ref\|YP_002216905.1\| crispr-associated protein Cas1 [Salmonella enterica subsp. enterica... gi\|194457040, gi... - gi\|194470676\|ref\|ZP_03076660.1\| crispr-associated protein Cas1 [Salmonella enterica subsp. enterica ... gi\|205334601, gi... - gi\|205334601\|gb\|EDZ21365.1\| crispr-associated protein Cas1 [Salmonella enterica subsp. enterica sero...	322.0	[0..1]	[303..1]
CAS1_GEOSL - CRISPR-associated endonuclease Cas1 OS=Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA...	321.0	[0..5]	[303..7]
gi\|16766244, gi\|... - gi\|16766244\|ref\|NP_461859.1\| putative cytoplasmic protein [Salmonella typhimurium LT2], gi\|16421488\|... gi\|168820356, gi... - gi\|205342791\|gb\|EDZ29555.1\| crispr-associated protein Cas1 [Salmonella enterica subsp. enterica sero... gi\|194448225, gi... - gi\|194448225\|ref\|YP_002046896.1\| crispr-associated protein Cas1 [Salmonella enterica subsp. enterica... gi\|205338141, gi... - gi\|205338141\|gb\|EDZ24905.1\| crispr-associated protein Cas1 [Salmonella enterica subsp. enterica sero...	321.0	[0..1]	[303..1]
gi\|196155691, gi... - gi\|88793938\|ref\|ZP_01109650.1\| hypothetical protein MADE_03916 [Alteromonas macleodii 'Deep ecotype'...	319.0	[0..1]	[304..1]
gi\|77918572, gi\|... - gi\|77918572\|ref\|YP_356387.1\| CRISPR-associated Cas1 family protein [Pelobacter carbinolicus DSM 2380...	318.0	[0..6]	[303..8]

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Predicted Domain #1

Region A:
Residues: [1-92]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTWLPLNPIP LKDRVSMIFL QYGQIDVIDG AFVLIDKTGI RTHIPVGSVA CIMLEPGTRV  60
   61 SHAAVRLAAQ VGTLLVWVGE AGVRVYASGQ PG

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.775	N/A	N/A	b.61.3	D-aminopeptidase, middle and C-terminal domains
View	Download	0.710	N/A	N/A	d.199.1	DNA-binding C-terminal domain of the transcription factor MotA
View	Download	0.708	N/A	N/A	d.129.2	Phosphoglucomutase, C-terminal domain
View	Download	0.695	N/A	N/A	d.109.1	Actin depolymerizing proteins
View	Download	0.649	N/A	N/A	d.109.1	Actin depolymerizing proteins

Predicted Domain #2

Region A:
Residues: [93-171]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GARSDKLLYQ AKLALDEDLR LKVVRKMFEL RFGEPAPARR SVEQLRGIEG SRVRATYALL  60
   61 AKQYGVTWNG RRYDPKDWE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.794	d.58.17	Metal-binding domain
View	Download	0.740	a.28.1	ACP-like
View	Download	0.714	d.58.49	YajQ-like
View	Download	0.703	d.58.17	Metal-binding domain
View	Download	0.686	d.58.17	Metal-binding domain

Predicted Domain #3

Region A:
Residues: [172-305]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KGDTINQCIS AATSCLYGVT EAAILAAGYA PAIGFVHTGK PLSFVYDIAD IIKFDTVVPK  60
   61 AFEIARRNPG EPDREVRLAC RDIFRSSKTL AKLIPLIEDV LAAGEIQPPA PPEDAQPVAI 120
  121 PLPVSLGDAG HRSS

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.461	N/A	N/A	a.24.9	alpha-catenin/vinculin
View	Download	0.428	N/A	N/A	a.24.14	FAT domain of focal adhesion kinase
View	Download	0.426	N/A	N/A	a.25.1	Ferritin-like
View	Download	0.416	N/A	N/A	a.47.2	t-snare proteins
View	Download	0.362	N/A	N/A	d.19.1	MHC antigen-recognition domain

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits