YRC Public Data Repository - Protein Structure Prediction

Protein:	YFHC_ECOLI, TADA...
Organism:	Escherichia coli
Length:	178 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YFHC_ECOLI, TADA....

Description	E-value	Query Range	Subject Range
gi\|115513905, gi... - gi\|117624781\|ref\|YP_853694.1\| tRNA-specific adenosine deaminase [Escherichia coli APEC O1], gi\|11551... gi\|218690674, gi... - gi\|218690674\|ref\|YP_002398886.1\| tRNA-specific adenosine deaminase [Escherichia coli ED1a], gi\|21842... gi\|218366248, gi... - gi\|218559479\|ref\|YP_002392392.1\| tRNA-specific adenosine deaminase [Escherichia coli S88], gi\|218366... TADA_ECO57 - tRNA-specific adenosine deaminase (EC 3.5.4.-) - Escherichia coli O157:H7 gi\|25303867, gi\|... - pir\|\|E85901 probable deaminase yfhC [imported] - Escherichia coli (strain O157:H7, substrain EDL933... gi\|189009982, gi... - gi\|189009982\|ref\|ZP_02803540.2\| tRNA-specific adenosine deaminase [Escherichia coli O157:H7 str. EC4... gi\|12516972, gi\|... - gi\|15803084\|ref\|NP_289115.1\| tRNA-specific adenosine deaminase [Escherichia coli O157:H7 EDL933], gi... gi\|91073458, gi\|... - gi\|91211884\|ref\|YP_541870.1\| tRNA-specific adenosine deaminase [Escherichia coli UTI89], gi\|91073458... gi\|187770595, gi... - gi\|187775816\|ref\|ZP_02798525.2\| tRNA-specific adenosine deaminase [Escherichia coli O157:H7 str. EC4... gi\|13362896, gi\|... - gi\|15832679\|ref\|NP_311452.1\| tRNA-specific adenosine deaminase [Escherichia coli O157:H7 str. Sakai]... gi\|82777934, gi\|... - gi\|82777934\|ref\|YP_404283.1\| tRNA-specific adenosine deaminase [Shigella dysenteriae Sd197], gi\|8124... gi\|110642721, gi... - gi\|110642721\|ref\|YP_670451.1\| tRNA-specific adenosine deaminase [Escherichia coli 536], gi\|110344313... gi\|194432153, gi... - gi\|194432153\|ref\|ZP_03064442.1\| tRNA-specific adenosine deaminase [Shigella dysenteriae 1012], gi\|19... gi\|237705067, gi... - gi\|237705067\|ref\|ZP_04535548.1\| tRNA-specific adenosine deaminase [Escherichia sp. 3_2_53FAA], gi\|22... gi\|190907120, gi... - gi\|191172647\|ref\|ZP_03034186.1\| tRNA-specific adenosine deaminase [Escherichia coli F11], gi\|1909071... gi\|189378592, gi... - gi\|189405736\|ref\|ZP_02823945.2\| tRNA-specific adenosine deaminase [Escherichia coli O157:H7 str. EC5... gi\|189405037, gi... - gi\|189405037\|ref\|ZP_02812923.2\| tRNA-specific adenosine deaminase [Escherichia coli O157:H7 str. EC8...	228.0	[0..1]	[178..1]
gi\|74313082, gi\|... - gi\|74313082\|ref\|YP_311501.1\| tRNA-specific adenosine deaminase [Shigella sonnei Ss046], gi\|73856559\|...	228.0	[0..1]	[178..1]
TADA_ECOL6 - tRNA-specific adenosine deaminase (EC 3.5.4.-) - Escherichia coli O6 gi\|26109329, gi\|... - gi\|26248923\|ref\|NP_754963.1\| tRNA-specific adenosine deaminase [Escherichia coli CFT073], gi\|2610932... gi\|227887593, gi... - gi\|227887593\|ref\|ZP_04005398.1\| tRNA-specific adenosine deaminase [Escherichia coli 83972], gi\|22783...	226.0	[0..1]	[178..1]
gi\|16761480 - gi\|16761480\|ref\|NP_457097.1\| tRNA-specific adenosine deaminase [Salmonella enterica subsp. enterica ... TADA_SALTI - tRNA-specific adenosine deaminase (EC 3.5.4.-) - Salmonella typhi gi\|16421115, gi\|... - gi\|16765888\|ref\|NP_461503.1\| tRNA-specific adenosine deaminase [Salmonella typhimurium LT2], gi\|1642... TADA_SALTY - tRNA-specific adenosine deaminase (EC 3.5.4.-) - Salmonella typhimurium gi\|29136448, gi\|... - gi\|29140823\|ref\|NP_804165.1\| tRNA-specific adenosine deaminase [Salmonella enterica subsp. enterica ... gi\|62181133, gi\|... - gi\|62181133\|ref\|YP_217550.1\| tRNA-specific adenosine deaminase [Salmonella enterica subsp. enterica ... lcl\|NC_016856.1_... - [gene=yfhC] [protein=tRNA-specific adenosine deaminase] [protein_id=YP_005238675.1] [location=comple... gi\|16503780, gi\|... - gi\|25303877\|pir\|\|AF0827 conserved hypothetical protein STY2814 [imported] - Salmonella enterica subs... gi\|224582890, gi... - gi\|224582890\|ref\|YP_002636688.1\| hypothetical protein SPC_1081 [Salmonella enterica subsp. enterica ...	222.0	[0..1]	[173..1]
gi\|197361490, gi... - gi\|197361490\|ref\|YP_002141126.1\| tRNA-specific adenosine deaminase [Salmonella enterica subsp. enter... gi\|56126812, gi\|... - gi\|56412555\|ref\|YP_149630.1\| tRNA-specific adenosine deaminase [Salmonella enterica subsp. enterica ...	222.0	[0..1]	[173..1]
gi\|90108581, gi\|... - gi\|90108581\|pdb\|1Z3A\|B Chain B, Crystal Structure Of Trna Adenosine Deaminase Tada From Escherichia ...	217.0	[0..11]	[178..1]
gi\|110616037, gi... - gi\|110806489\|ref\|YP_690009.1\| tRNA-specific adenosine deaminase [Shigella flexneri 5 str. 8401], gi\|...	217.0	[0..12]	[178..1]
gi\|90438699, gi\|... - gi\|90579814\|ref\|ZP_01235622.1\| Putative cytosine/adenosine deaminase [Vibrio angustum S14], gi\|90438...	207.0	[0..11]	[175..1]
gi\|116184449 - gi\|116184449\|ref\|ZP_01474386.1\| hypothetical protein VEx2w_02003038 [Vibrio sp. Ex25]	206.0	[0..4]	[177..14]
gi\|89051074, gi\|... - gi\|89073121\|ref\|ZP_01159660.1\| Putative cytosine/adenosine deaminase [Photobacterium sp. SKA34], gi\|...	205.0	[0..11]	[175..1]

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Predicted Domain #1

Region A:
Residues: [1-178]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRRAFITGVF FLSEVEFSHE YWMRHALTLA KRAWDEREVP VGAVLVHNNR VIGEGWNRPI  60
   61 GRHDPTAHAE IMALRQGGLV MQNYRLIDAT LYVTLEPCVM CAGAMIHSRI GRVVFGARDA 120
  121 KTGAAGSLMD VLHHPGMNHR VEITEGILAD ECAALLSDFF RMRRQEIKAQ KKAQSSTD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	57.0
Match:	1z3aA
Description:	Crystal structure of tRNA adenosine deaminase TadA from Escherichia coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
cytidine deaminase activity	4.1319373737356	bayes_pls_golite062009
deaminase activity	2.76997916054448	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	2.27736397496642	bayes_pls_golite062009
catalytic activity	1.70756445127105	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	1.51294035758003	bayes_pls_golite062009
methyltransferase activity	1.24697538679504	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	1.16679252289538	bayes_pls_golite062009
phosphoribosylaminoimidazolecarboxamide formyltransferase activity	0.827438033765078	bayes_pls_golite062009
IMP cyclohydrolase activity	0.34666532377291	bayes_pls_golite062009
cyclohydrolase activity	0.308525511259279	bayes_pls_golite062009
hydrolase activity	0.278944100740279	bayes_pls_golite062009
hydroxymethyl-, formyl- and related transferase activity	0.1546696349714	bayes_pls_golite062009
binding	0.150539409748188	bayes_pls_golite062009
transferase activity	0.067547691257636	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: