YRC Public Data Repository - Protein Structure Prediction

Protein:	YEJH_ECOLI
Organism:	Escherichia coli
Length:	586 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YEJH_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|213581648 - gi\|213581648\|ref\|ZP_03363474.1\| putative helicase [Salmonella enterica subsp. enterica serovar Typhi... gi\|213424221 - gi\|213424221\|ref\|ZP_03357080.1\| putative helicase [Salmonella enterica subsp. enterica serovar Typhi... gi\|224467806, gi... - gi\|224583279\|ref\|YP_002637077.1\| putative helicase [Salmonella enterica subsp. enterica serovar Para... lcl\|NC_016856.1_... - [gene=yejH] [protein=putative ATP-dependent helicase] [protein_id=YP_005238286.1] [location=2376101.... gi\|214000104 - gi\|214000104\|ref\|ZP_03410839.1\| putative helicase [Salmonella enterica subsp. enterica serovar Typhi... gi\|194442899, gi... - gi\|194442899\|ref\|YP_002041498.1\| putative helicase [Salmonella enterica subsp. enterica serovar Newp... gi\|168818046, gi... - gi\|205345089\|gb\|EDZ31853.1\| putative helicase [Salmonella enterica subsp. enterica serovar Weltevred... gi\|197938965, gi... - gi\|198244449\|ref\|YP_002216307.1\| putative helicase [Salmonella enterica subsp. enterica serovar Dubl... gi\|197239936, gi... - gi\|197261681\|ref\|ZP_03161755.1\| putative helicase [Salmonella enterica subsp. enterica serovar Saint... gi\|205324027, gi... - gi\|205324027\|gb\|EDZ11866.1\| putative helicase [Salmonella enterica subsp. enterica serovar Saintpaul... gi\|195631392, gi... - gi\|195631392\|gb\|EDX49952.1\| putative helicase [Salmonella enterica subsp. enterica serovar Newport s... gi\|205329207, gi... - gi\|205329207\|gb\|EDZ15971.1\| putative helicase [Salmonella enterica subsp. enterica serovar 4,[5],12:... gi\|238913795 - gi\|238913795\|ref\|ZP_04657632.1\| putative helicase [Salmonella enterica subsp. enterica serovar Tenne... gi\|25376544, gi\|... - gi\|25376544\|pir\|\|AH0785 probable helicase STY2460 [imported] - Salmonella enterica subsp. enterica s... gi\|16765552, gi\|... - gi\|16765552\|ref\|NP_461167.1\| putative ATP-dependent helicase [Salmonella typhimurium LT2], gi\|164207... gi\|29141141, gi\|... - gi\|29141141\|ref\|NP_804483.1\| putative helicase [Salmonella enterica subsp. enterica serovar Typhi st... gi\|16761164 - gi\|16761164\|ref\|NP_456781.1\| putative helicase [Salmonella enterica subsp. enterica serovar Typhi st...	407.0	[0..1]	[586..1]
gi\|62128443, gi\|... - gi\|62180810\|ref\|YP_217227.1\| putative ATP-dependent helicase [Salmonella enterica subsp. enterica se...	407.0	[0..1]	[586..1]
gi\|91211474, gi\|... - gi\|91211474\|ref\|YP_541460.1\| hypothetical protein UTI89_C2461 [Escherichia coli UTI89], gi\|91073048\|... gi\|226901023, gi... - gi\|237704657\|ref\|ZP_04535138.1\| conserved hypothetical protein [Escherichia sp. 3_2_53FAA], gi\|22690... gi\|26248567, gi\|... - gi\|26248567\|ref\|NP_754607.1\| hypothetical protein c2721 [Escherichia coli CFT073], gi\|26108972\|gb\|AA... gi\|218365874, gi... - gi\|218559105\|ref\|YP_002392018.1\| putative nucleic acid ATP-dependent helicase [Escherichia coli S88]... gi\|117624382, gi... - gi\|117624382\|ref\|YP_853295.1\| putative ATP-dependet helicase [Escherichia coli APEC O1], gi\|11551350...	406.0	[0..1]	[586..1]
gi\|110806163, gi... - gi\|110806163\|ref\|YP_689683.1\| putative ATP-dependent helicase [Shigella flexneri 5 str. 8401], gi\|11... gi\|218432813, gi... - gi\|218705716\|ref\|YP_002413235.1\| putative nucleic acid ATP-dependent helicase [Escherichia coli UMN0... gi\|75259658, gi\|... - gi\|75259658\|ref\|ZP_00730960.1\| COG1061: DNA or RNA helicases of superfamily II [Escherichia coli E22... gi\|75211602, gi\|... - gi\|75211602\|ref\|ZP_00711681.1\| COG1061: DNA or RNA helicases of superfamily II [Escherichia coli B17... gi\|75176195, gi\|... - gi\|75176195\|ref\|ZP_00696353.1\| COG1061: DNA or RNA helicases of superfamily II [Shigella boydii BS51...	406.0	[0..1]	[586..1]
gi\|12516516, gi\|... - gi\|15802740\|ref\|NP_288767.1\| putative ATP-dependent helicase [Escherichia coli O157:H7 EDL933], gi\|1... gi\|208735036, gi... - gi\|208813759\|ref\|ZP_03255088.1\| putative helicase [Escherichia coli O157:H7 str. EC4045], gi\|2087350... gi\|15832330, gi\|... - gi\|15832330\|ref\|NP_311103.1\| putative ATP-dependent helicase [Escherichia coli O157:H7], gi\|13362545... gi\|208727398, gi... - gi\|208807597\|ref\|ZP_03249934.1\| putative helicase [Escherichia coli O157:H7 str. EC4206], gi\|2087273... gi\|195935566 - gi\|195935566\|ref\|ZP_03080948.1\| putative ATP-dependent helicase [Escherichia coli O157:H7 str. EC402... gi\|189371367, gi... - gi\|189371367\|gb\|EDU89783.1\| putative helicase [Escherichia coli O157:H7 str. EC869], gi\|168789003\|re... gi\|217319273, gi... - gi\|217326906\|ref\|ZP_03442989.1\| putative helicase [Escherichia coli O157:H7 str. TW14588], gi\|217319... gi\|209159710, gi... - gi\|209398310\|ref\|YP_002271598.1\| putative helicase [Escherichia coli O157:H7 str. EC4115], gi\|209159... gi\|208818904, gi... - gi\|208818904\|ref\|ZP_03259224.1\| putative helicase [Escherichia coli O157:H7 str. EC4042], gi\|2087390... gi\|188016124, gi... - gi\|188016124\|gb\|EDU54246.1\| putative helicase [Escherichia coli O157:H7 str. EC4113], gi\|168749591\|r... gi\|189001985, gi... - gi\|189001985\|gb\|EDU70971.1\| putative helicase [Escherichia coli O157:H7 str. EC4076], gi\|168780037\|r... gi\|187771099, gi... - gi\|187771099\|gb\|EDU34943.1\| putative helicase [Escherichia coli O157:H7 str. EC4196], gi\|168773095\|r... gi\|189362992, gi... - gi\|189362992\|gb\|EDU81411.1\| putative helicase [Escherichia coli O157:H7 str. EC4486], gi\|168767808\|r... gi\|189354271, gi... - gi\|189354271\|gb\|EDU72690.1\| putative helicase [Escherichia coli O157:H7 str. EC4401], gi\|168759073\|r... gi\|15832330, gi\|... - gi\|15832330\|ref\|NP_311103.1\| putative ATP-dependent helicase [Escherichia coli O157:H7 str. Sakai], ... gi\|254593485, gi... - gi\|254794085\|ref\|YP_003078922.1\| predicted ATP-dependent helicase [Escherichia coli O157:H7 str. TW1... gi\|25376539, gi\|... - pir\|\|F85857 probable ATP-dependent helicase yejH [imported] - Escherichia coli (strain O157:H7, subs...	406.0	[0..1]	[586..1]
gi\|24113573, gi\|... - gi\|24113573\|ref\|NP_708083.1\| putative ATP-dependent helicase [Shigella flexneri 2a str. 301], gi\|240... gi\|30041880, gi\|... - gi\|30063627\|ref\|NP_837798.1\| putative ATP-dependent helicase [Shigella flexneri 2a str. 2457T], gi\|3...	406.0	[0..1]	[586..1]
gi\|74312705, gi\|... - gi\|74312705\|ref\|YP_311124.1\| putative ATP-dependent helicase [Shigella sonnei Ss046], gi\|73856182\|gb...	405.0	[0..1]	[586..1]
gi\|218352531, gi... - gi\|218695799\|ref\|YP_002403466.1\| putative nucleic acid ATP-dependent helicase [Escherichia coli 5598... gi\|209919644, gi... - gi\|209919644\|ref\|YP_002293728.1\| putative ATP-dependent helicase [Escherichia coli SE11], gi\|2099129... gi\|218554754, gi... - gi\|218554754\|ref\|YP_002387667.1\| putative nucleic acid ATP-dependent helicase [Escherichia coli IAI1... gi\|157076768, gi... - gi\|75186982\|ref\|ZP_00700249.1\| COG1061: DNA or RNA helicases of superfamily II [Escherichia coli E24...	405.0	[0..1]	[586..1]
gi\|110642395, gi... - gi\|110642395\|ref\|YP_670125.1\| hypothetical protein ECP_2225 [Escherichia coli 536], gi\|110343987\|gb\|... gi\|75243002, gi\|... - gi\|75243002\|ref\|ZP_00726708.1\| COG1061: DNA or RNA helicases of superfamily II [Escherichia coli F11...	405.0	[0..1]	[586..1]
gi\|157161666, gi... - gi\|75196229\|ref\|ZP_00706299.1\| COG1061: DNA or RNA helicases of superfamily II [Escherichia coli HS]...	405.0	[0..1]	[586..1]

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Predicted Domain #1

Region A:
Residues: [1-74]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIFTLRPYQQ EAVDATLNHF RRHKTPAVIV LPTGAGKSLV IAELARLARG RVLVLAHVKE  60
   61 LVAQNHAKYQ ALGL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	62.69897
Match:	2db3A
Description:	No description for 2db3A was found.

Predicted Domain #2

Region A:
Residues: [75-486]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EADIFAAGLK RKESHGKVVF GSVQSVARNL DAFQGEFSLL IVDECHRIGD DEESQYQQIL  60
   61 THLTKVNPHL RLLGLTATPF RLGKGWIYQF HYHGMVRGDE KALFRDCIYE LPLRYMIKHG 120
  121 YLTPPERLDM PVVQYDFSRL QAQSNGLFSE ADLNRELKKQ QRITPHIISQ IMEFAATRKG 180
  181 VMIFAATVEH AKEIVGLLPA EDAALITGDT PGAERDVLIE NFKAQRFRYL VNVAVLTTGF 240
  241 DAPHVDLIAI LRPTESVSLY QQIVGRGLRL APGKTDCLIL DYAGNPHDLY APEVGTPKGK 300
  301 SDNVPVQVFC PACGFANTFW GKTTADGTLI EHFGRRCQGW FEDDDGHREQ CDFRFRFKNC 360
  361 PQCNAENDIA ARRCRECDTV LVDPDDMLKA ALRLKDALVL RCSGMSLQHG HD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	16.522879
Match:	1c4oA
Description:	Nucleotide excision repair enzyme UvrB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.37148167194523	bayes_pls_golite062009
hydrolase activity	0.226001870533921	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [487-586]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKGEWLKITY YDEDGADVSE RFRLQTPAQR TAFEQLFIRP HTRTPGIPLR WITAADILAQ  60
   61 QALLRHPDFV VARMKGQYWQ VREKVFDYEG RFRLAHELRG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: