YRC Public Data Repository - Protein Structure Prediction

Protein:	YEIN_ECOLI
Organism:	Escherichia coli
Length:	312 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YEIN_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|242232470, gi... - gi\|242255987\|ref\|ZP_04800885.1\| Indigoidine synthase A family protein [Thermoanaerobacter sp. X513],... gi\|166853167, gi... - gi\|167038927\|ref\|YP_001661912.1\| indigoidine synthase A family protein [Thermoanaerobacter sp. X514]...	484.0	[0..8]	[310..2]
gi\|157155991, gi... - gi\|75186962\|ref\|ZP_00700229.1\| COG2313: Uncharacterized enzyme involved in pigment biosynthesis [Esc... gi\|209912883, gi... - gi\|209919624\|ref\|YP_002293708.1\| hypothetical protein ECSE_2433 [Escherichia coli SE11], gi\|20991288...	482.0	[0..1]	[312..1]
gi\|83571065, gi\|... - gi\|83571065\|ref\|ZP_00922506.1\| COG2313: Uncharacterized enzyme involved in pigment biosynthesis [Shi...	482.0	[0..1]	[312..1]
gi\|188488145, gi... - gi\|75514496\|ref\|ZP_00736774.1\| COG2313: Uncharacterized enzyme involved in pigment biosynthesis [Esc... gi\|157161646, gi... - gi\|75196209\|ref\|ZP_00706279.1\| COG2313: Uncharacterized enzyme involved in pigment biosynthesis [Esc... gi\|194436084, gi... - gi\|83588146\|ref\|ZP_00926771.1\| COG2313: Uncharacterized enzyme involved in pigment biosynthesis [Esc... gi\|254288940, gi... - gi\|254288940\|ref\|YP_003054688.1\| hypothetical protein ECD_02094 [Escherichia coli BL21(DE3)], gi\|253... gi\|242377805, gi... - gi\|251785532\|ref\|YP_002999836.1\| hypothetical protein B21_02053 [Escherichia coli BL21], gi\|24237780... gi\|254162179, gi... - gi\|254162179\|ref\|YP_003045287.1\| hypothetical protein ECB_02094 [Escherichia coli B str. REL606], gi... gi\|170019519, gi... - gi\|170019519\|ref\|YP_001724473.1\| indigoidine synthase A family protein [Escherichia coli ATCC 8739],... gi\|124501798, gi... - gi\|124526742\|ref\|ZP_01698651.1\| Indigoidine synthase A family protein [Escherichia coli B], gi\|12450...	482.0	[0..1]	[312..1]
gi\|208820009, gi... - gi\|208820009\|ref\|ZP_03260329.1\| indigoidine synthase A like protein [Escherichia coli O157:H7 str. E... gi\|209160643, gi... - gi\|209399243\|ref\|YP_002271577.1\| indigoidine synthase A like protein [Escherichia coli O157:H7 str. ... gi\|217319924, gi... - gi\|217327557\|ref\|ZP_03443640.1\| indigoidine synthase A like protein [Escherichia coli O157:H7 str. T... gi\|189371333, gi... - gi\|189371333\|gb\|EDU89749.1\| indigoidine synthase A like protein [Escherichia coli O157:H7 str. EC869... gi\|189375275, gi... - gi\|189375275\|gb\|EDU93691.1\| indigoidine synthase A like protein [Escherichia coli O157:H7 str. EC508... gi\|195935544 - gi\|195935544\|ref\|ZP_03080926.1\| hypothetical protein EscherichcoliO157_03647 [Escherichia coli O157:... gi\|208814584, gi... - gi\|208814584\|ref\|ZP_03255913.1\| indigoidine synthase A like protein [Escherichia coli O157:H7 str. E... gi\|168763827, gi... - gi\|189366081\|gb\|EDU84497.1\| indigoidine synthase A like protein [Escherichia coli O157:H7 str. EC450... gi\|168767784, gi... - gi\|189362968\|gb\|EDU81387.1\| indigoidine synthase A like protein [Escherichia coli O157:H7 str. EC448... gi\|168773118, gi... - gi\|187771204\|gb\|EDU35048.1\| indigoidine synthase A like protein [Escherichia coli O157:H7 str. EC419... gi\|168780014, gi... - gi\|189001903\|gb\|EDU70889.1\| indigoidine synthase A like protein [Escherichia coli O157:H7 str. EC407... gi\|168752603, gi... - gi\|188013603\|gb\|EDU51725.1\| indigoidine synthase A like protein [Escherichia coli O157:H7 str. EC411... gi\|168758828, gi... - gi\|189354427\|gb\|EDU72846.1\| indigoidine synthase A like protein [Escherichia coli O157:H7 str. EC440... gi\|25351900, gi\|... - pir\|\|C85855 hypothetical protein yeiN [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|15802721, gi\|... - gi\|15802721\|ref\|NP_288748.1\| hypothetical protein Z3422 [Escherichia coli O157:H7 EDL933], gi\|125164... gi\|15832311, gi\|... - gi\|15832311\|ref\|NP_311084.1\| hypothetical protein ECs3057 [Escherichia coli O157:H7 str. Sakai], gi\|... gi\|15832311, gi\|... - gi\|15832311\|ref\|NP_311084.1\| hypothetical protein ECs3057 [Escherichia coli O157:H7], gi\|13362526\|db... gi\|254794064, gi... - gi\|254794064\|ref\|YP_003078901.1\| hypothetical protein ECSP_3043 [Escherichia coli O157:H7 str. TW143...	481.0	[0..1]	[312..1]
gi\|192931954, gi... - gi\|75259637\|ref\|ZP_00730939.1\| COG2313: Uncharacterized enzyme involved in pigment biosynthesis [Esc... gi\|194414786, gi... - gi\|75211581\|ref\|ZP_00711660.1\| COG2313: Uncharacterized enzyme involved in pigment biosynthesis [Esc...	481.0	[0..1]	[312..1]
gi\|167038341, gi... - gi\|76795413\|ref\|ZP_00777786.1\| Indigoidine synthase A like protein [Thermoanaerobacter ethanolicus A... gi\|241902612, gi... - gi\|241902612\|ref\|ZP_04787345.1\| Indigoidine synthase A family protein [Thermoanaerobacter brockii su...	481.0	[0..8]	[310..2]
gi\|192955606, gi... - gi\|75234053\|ref\|ZP_00718470.1\| COG2313: Uncharacterized enzyme involved in pigment biosynthesis [Esc...	480.0	[0..1]	[312..1]
gi\|110806141, gi... - gi\|110806141\|ref\|YP_689661.1\| hypothetical protein SFV_2240 [Shigella flexneri 5 str. 8401], gi\|1106...	480.0	[0..1]	[312..1]
gi\|24113552, gi\|... - gi\|24113552\|ref\|NP_708062.1\| hypothetical protein SF2250 [Shigella flexneri 2a str. 301], gi\|2405260... gi\|30041859, gi\|... - gi\|30063606\|ref\|NP_837777.1\| hypothetical protein S2379 [Shigella flexneri 2a str. 2457T], gi\|300418...	479.0	[0..1]	[312..1]

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Predicted Domain #1

Region A:
Residues: [1-312]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSELKISPEL LQISPEVQDA LKNKKPVVAL ESTIISHGMP FPQNAQTAIE VEETIRKQGA  60
   61 VPATIAIIGG VMKVGLSKEE IELLGREGHN VTKVSRRDLP FVVAAGKNGA TTVASTMIIA 120
  121 ALAGIKVFAT GGIGGVHRGA EHTFDISADL QELANTNVTV VCAGAKSILD LGLTTEYLET 180
  181 FGVPLIGYQT KALPAFFCRT SPFDVSIRLD SASEIARAMV VKWQSGLNGG LVVANPIPEQ 240
  241 FAMPEHTINA AIDQAVAEAE AQGVIGKEST PFLLARVAEL TGGDSLKSNI QLVFNNAILA 300
  301 SEIAKEYQRL AG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	83.39794
Match:	1vkmA
Description:	Crystal structure of conserved hypothetical protein possibly involved in carbohydrate metabolism (TM1464) from Thermotoga maritima at 1.90 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.693821880093629	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: